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| <meta charset="UTF-8"> | | <meta charset="UTF-8"> |
| <meta name="viewport" content="width=device-width,initial-scale=1.0"/> | | <meta name="viewport" content="width=device-width,initial-scale=1.0"/> |
− | <title>Our Story</title> | + | <title>GLP.exe - Our Story</title> |
| <link rel="stylesheet" href="https://2019.igem.org/Team:Tuebingen/normalize_css"> | | <link rel="stylesheet" href="https://2019.igem.org/Team:Tuebingen/normalize_css"> |
| <link rel='stylesheet' href='https://2019.igem.org/Team:Tuebingen/swiper_css?action=raw&ctype=text/css'> | | <link rel='stylesheet' href='https://2019.igem.org/Team:Tuebingen/swiper_css?action=raw&ctype=text/css'> |
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| <section id="nav-placeholder"> | | <section id="nav-placeholder"> |
− | <nav class="shadow navbar navbar-expand-md navbar-dark fixed-top"
| + | <nav class="shadow navbar navbar-expand-md navbar-dark fixed-top" |
| style="background-color: rgba(30, 30, 30, 0.3); z-index: 100;"> | | style="background-color: rgba(30, 30, 30, 0.3); z-index: 100;"> |
| <a class="navbar-brand" href="https://2019.igem.org/Team:Tuebingen"> | | <a class="navbar-brand" href="https://2019.igem.org/Team:Tuebingen"> |
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| <div class="swiper-slide-content"><span class="timeline-year">August</span> | | <div class="swiper-slide-content"><span class="timeline-year">August</span> |
| <h4 class="timeline-title">RNA-Seq Experiments at EMBL and NCCT</h4> | | <h4 class="timeline-title">RNA-Seq Experiments at EMBL and NCCT</h4> |
− | <p class="timeline-text">In our project, we characterised our probiotic strain E. coli Nissle and | + | <p class="timeline-text">In our project, we characterised our probiotic strain <i>E. coli</i> Nissle and |
| conducted RNA-Seq experiments to analyse its response to several stress factors. | | conducted RNA-Seq experiments to analyse its response to several stress factors. |
| The experiments were performed by us at the EMBL in Heidelberg, as well as the NCCT in | | The experiments were performed by us at the EMBL in Heidelberg, as well as the NCCT in |
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| data-year="October"> | | data-year="October"> |
| <div class="swiper-slide-content"><span class="timeline-year">October</span> | | <div class="swiper-slide-content"><span class="timeline-year">October</span> |
− | <h4 class="timeline-title">University’s special price for extraordinary student engagement</h4> | + | <h4 class="timeline-title">University’s special prize for extraordinary student engagement</h4> |
− | <p class="timeline-text">In the context of iGEM we were awarded the university’s special price | + | <p class="timeline-text">In the context of iGEM we were awarded the university’s special prize |
| for extraordinary student engagement by the Eberhard Karls University Tuebingen. | | for extraordinary student engagement by the Eberhard Karls University Tuebingen. |
− | The special price is a great honor and is awarded once a year to one highly engaged | + | The special prize is a great honor and is awarded once a year to one highly engaged |
| group of students during the semester opening ceremony ‘Dies Universitatis’. | | group of students during the semester opening ceremony ‘Dies Universitatis’. |
| During that event, we also set up a booth where we informed students about iGEM and our project.</p> | | During that event, we also set up a booth where we informed students about iGEM and our project.</p> |
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| <div id="image-popups"> | | <div id="image-popups"> |
| | | |
− | <h3 style="font-family:'Righteous'; color:#2ecc71;">Project</h3>
| + | <h3 style="font-family:'Righteous'; color:#2ecc71;">Project</h3> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Development and research until March 2019</h3>
| + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Development and research until March 2019</h3> |
| <p> | | <p> |
− | Since a few of our team members’ relatives enormously suffer from Diabetes Mellitus Type II, we, | + | Since a few of our team members’ relatives enormously suffer from Type 2 Diabetes Mellitus, we, |
| as a team, decided to focus our efforts on improving their lives. The most important issues | | as a team, decided to focus our efforts on improving their lives. The most important issues |
| that were brought up by the affected were severe side effects and the need of daily injections. | | that were brought up by the affected were severe side effects and the need of daily injections. |
| As a result, we decided to look into the field of engineered probiotics and their possible application | | As a result, we decided to look into the field of engineered probiotics and their possible application |
| for the threatening issue of the world wide Diabetes epidemic. Consequently, after further research, | | for the threatening issue of the world wide Diabetes epidemic. Consequently, after further research, |
− | we chose E. coli Nissle 1917 as our platform organism due to its unique characteristics and beneficial | + | we chose <i>E. coli</i> Nissle 1917 as our platform organism due to its unique characteristics and beneficial |
| use as probiotic (<a href="https://2019.igem.org/Team:Tuebingen/Nissle" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Nissle","_self");'>Project/Nissle</a>). | | use as probiotic (<a href="https://2019.igem.org/Team:Tuebingen/Nissle" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Nissle","_self");'>Project/Nissle</a>). |
| </p> | | </p> |
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| | | |
| <h2 style="font-family:'Righteous'; color:#2ecc71;">March 2019</h2> | | <h2 style="font-family:'Righteous'; color:#2ecc71;">March 2019</h2> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Contacting Prof. Timo Müller</h3>
| + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Contacting Prof. Timo Müller</h3> |
| <p> | | <p> |
| We contacted Prof. Timo Müller from the Helmholtz Institute in Munich | | We contacted Prof. Timo Müller from the Helmholtz Institute in Munich |
| (<a href="https://2019.igem.org/Team:Tuebingen/Experts" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Experts","_self");'>Human Practices/Experts</a>), | | (<a href="https://2019.igem.org/Team:Tuebingen/Experts" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Experts","_self");'>Human Practices/Experts</a>), |
− | who helped us determine that Glucagon like peptide 1 (GLP-1) itself is not suitable as a | + | who helped us determine that Glucagon like peptide 1 (GLP-1) itself is not suitable as a therapeutic. Therefore, |
− | therapeutic. Therefore, we researched GLP-1 analogs and finally decided on Exendin-4,
| + | we researched GLP-1 analogs and finally decided on Exendin-4, a GLP-1 analogue originating from the |
− | a GLP-1 analogue originating from the lizard Heloderma suspectum. The human analogue
| + | lizard Heloderma suspectum. The human analogue to Exendin-4 is GLP-1, which is secreted from the L-cells |
− | to Exendin-4 is GLP-1, which is secreted from the L-cells in the small intestine when
| + | in the small intestine when nutrients are available in the gut. To further mimic the natural state of |
− | nutrients are available in the gut. To further mimic the natural state of incretin
| + | incretin mimetics, we developed a glucose-sensing Catabolite repression - Tet-Repressor system |
− | mimetics, we developed a glucose-sensing Catabolite repression - Tet-Repressor system | + | |
| (<a href="https://2019.igem.org/Team:Tuebingen/Parts" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Parts","_self");'>Parts/Parts Overview</a>). | | (<a href="https://2019.igem.org/Team:Tuebingen/Parts" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Parts","_self");'>Parts/Parts Overview</a>). |
| </p> | | </p> |
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| | | |
| <h2 style="font-family:'Righteous'; color:#2ecc71;">April 2019</h2> | | <h2 style="font-family:'Righteous'; color:#2ecc71;">April 2019</h2> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Meet-up with Prof. Andreas Fritsche</h3> | + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Meet-up with Prof. Andreas Fritsche</h3> |
| <p> | | <p> |
− | We met with Prof. Andreas Fritsche,deputy director of the Institute for Diabetes Research and Metabolic | + | We met with Prof. Andreas Fritsche, deputy director of the Institute for Diabetes Research and Metabolic |
− | Disease of the Helmholtz Institute Munich at the Eberhard-Karls University Tuebingen, to gather | + | Disease of the Helmholtz Institute Munich at the Eberhard Karls University Tuebingen, to gather |
| information about Diabetes patients and their willingness to use a genetically engineered organism | | information about Diabetes patients and their willingness to use a genetically engineered organism |
| as a therapeutic. In general, Prof. Fritsche explained that many people affected by Type 2 Diabetes | | as a therapeutic. In general, Prof. Fritsche explained that many people affected by Type 2 Diabetes |
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| <a href="https://2019.igem.org/Team:Tuebingen/Public_Engagement" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Public_Engagement","_self");'>Human Practices/Education & Public Engagement</a>). | | <a href="https://2019.igem.org/Team:Tuebingen/Public_Engagement" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Public_Engagement","_self");'>Human Practices/Education & Public Engagement</a>). |
| </p> | | </p> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Implementation of the CRISPR/Cas3 based kill switch system provided by Pengfei Xia</h3> | + | <h3 style="font-family: Righteous; color: #2ecc71;">Implementation of the CRISPR/Cas3 based kill switch system provided by Dr. Pengfei Xia</h3> |
| <p> | | <p> |
| Integrating the public’s concerns about using GMOs, and to make our probiotic compatible with both | | Integrating the public’s concerns about using GMOs, and to make our probiotic compatible with both |
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| </div> | | </div> |
| | | |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Meeting with Synovo to talk about the business side and the project</h3> | + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Meeting with Synovo to talk about the business side and the project</h3> |
| <p> | | <p> |
| To get further input on our project and first insights into a biotechnological company, we contacted | | To get further input on our project and first insights into a biotechnological company, we contacted |
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| | | |
| <h2 style="font-family:'Righteous'; color:#2ecc71;">May 2019</h2> | | <h2 style="font-family:'Righteous'; color:#2ecc71;">May 2019</h2> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Biosafety consulting with Dr. Jörg Schibel and Dr. Brigitte Walderich</h3>
| + | |
| <div class="row"> | | <div class="row"> |
− | <div class="col-12"> | + | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Biosafety consulting with Dr. Jörg Schibel and Dr. Brigitte Walderich</h3> |
| + | |
| <p> | | <p> |
| Since we required CPPs (<a href="https://2019.igem.org/Team:Tuebingen/Description" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Description","_self");'>Project/Overview</a>) | | Since we required CPPs (<a href="https://2019.igem.org/Team:Tuebingen/Description" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Description","_self");'>Project/Overview</a>) |
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| </div> | | </div> |
| | | |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Survey presentation at the Science Slam</h3>
| + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Survey presentation at the Science Slam</h3> |
| <p> | | <p> |
| To include the public in our project, we had a brief talk at a Science Slam hosted by the Medical | | To include the public in our project, we had a brief talk at a Science Slam hosted by the Medical |
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| </div> | | </div> |
| | | |
− | <h3 style="font-family:'Righteous'; color:#2ecc71;">From May 2019</h3>
| + | <h3 style="font-family:'Righteous'; color:#2ecc71;">From May 2019</h3> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Collaboration with the Institute of Innate Immunity Bonn (AG Eike Latz)</h3>
| + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Collaboration with the Institute of Innate Immunity Bonn (AG Eike Latz)</h3> |
| <p> | | <p> |
| At the iGEM Spring Festival organised by iGEM Düsseldorf, we heard a talk about Diabetes and its | | At the iGEM Spring Festival organised by iGEM Düsseldorf, we heard a talk about Diabetes and its |
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| | | |
| <h3 style="font-family:'Righteous'; color:#2ecc71;">From May/June 2019</h3> | | <h3 style="font-family:'Righteous'; color:#2ecc71;">From May/June 2019</h3> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Intense WetLab work at the Wohlleben Labor</h3> | + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Intense WetLab work at the Wohlleben Labor</h3> |
| <p> | | <p> |
| Our projects required intensive cloning of multiple regulatory elements | | Our projects required intensive cloning of multiple regulatory elements |
| (<a href="https://2019.igem.org/Team:Tuebingen/Notebook" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Notebook","_self");'>Project/Notebook</a>). For the parts, we planned to | | (<a href="https://2019.igem.org/Team:Tuebingen/Notebook" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Notebook","_self");'>Project/Notebook</a>). For the parts, we planned to |
| use Biobricks that were sent to us with the 2019 shipping, Biobrick sequences from the iGEM’s | | use Biobricks that were sent to us with the 2019 shipping, Biobrick sequences from the iGEM’s |
− | database, as well as new sequences unique to our project. For the cloning, we used E. Coli | + | database, as well as new sequences unique to our project. For the cloning, we used <i>E. coli</i> |
| DH5alpha cells, as they allow for easier manipulation. As mentioned above, our final organism | | DH5alpha cells, as they allow for easier manipulation. As mentioned above, our final organism |
− | was E. Coli Nissle 1917. However, we did not have a lot of knowledge about the probiotic and also | + | was <i>E. coli</i> Nissle 1917. However, we did not have a lot of knowledge about the probiotic and also |
− | found that, within the iGEM competition, E. Coli Nissle 1917 was not properly characterized yet. | + | found that, within the iGEM competition, <i>E. coli</i> Nissle 1917 was not properly characterized yet. |
| </p> | | </p> |
| </div> | | </div> |
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| | | |
| <h2 style="font-family:'Righteous'; color:#2ecc71;">June 2019</h2> | | <h2 style="font-family:'Righteous'; color:#2ecc71;">June 2019</h2> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Modeling and characterization of E. Coli Nissle 1917</h3> | + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Modeling and characterization of <i>E. coli</i> Nissle 1917</h3> |
| <p> | | <p> |
| To gain knowledge on our chassis organism, we decided to make use of a metabolic model of E. | | To gain knowledge on our chassis organism, we decided to make use of a metabolic model of E. |
− | Coli Nissle 1917. Due to the fact that no metabolic model of E. Coli Nissle 1917 was available yet, | + | Coli Nissle 1917. Due to the fact that no metabolic model of <i>E. coli</i> Nissle 1917 was available yet, |
| we contacted Prof. Dr. Andreas Dräger who is an expert in metabolic modeling. Professor Dräger | | we contacted Prof. Dr. Andreas Dräger who is an expert in metabolic modeling. Professor Dräger |
| introduced CarveMe as a novel tool for the creation of metabolic models to us and gave us very valuable | | introduced CarveMe as a novel tool for the creation of metabolic models to us and gave us very valuable |
| tipps for our subsequent modelling approaches. Inspired by our Advanced Transcriptomics lectures | | tipps for our subsequent modelling approaches. Inspired by our Advanced Transcriptomics lectures |
− | by Prof. Dr. Kay Nieselt, we decided to characterize the transcriptome of E. Coli Nissle 1917 under | + | by Prof. Dr. Kay Nieselt, we decided to characterize the transcriptome of <i>E. coli</i> Nissle 1917 under |
| various stress conditions. As a result, we required a vast amount of data generated by the WetLab | | various stress conditions. As a result, we required a vast amount of data generated by the WetLab |
| such as growth curves under different conditions (<a href="https://2019.igem.org/Team:Tuebingen/Nissle" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Nissle","_self");'>Project/Nissle</a>). | | such as growth curves under different conditions (<a href="https://2019.igem.org/Team:Tuebingen/Nissle" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Nissle","_self");'>Project/Nissle</a>). |
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| | | |
| <h3 style="font-family:'Righteous'; color:#2ecc71;">June/July 2019</h3> | | <h3 style="font-family:'Righteous'; color:#2ecc71;">June/July 2019</h3> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Collaboration with iGEM Costa Rica and iGEM TAS Taipei on the SDGs</h3>
| + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Collaboration with iGEM Costa Rica and iGEM TAS Taipei on the SDGs</h3> |
| <p> | | <p> |
| The United Nations’ (UN) Sustainable Development Goals (SDGs) | | The United Nations’ (UN) Sustainable Development Goals (SDGs) |
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| | | |
| <h3 style="font-family:'Righteous'; color:#2ecc71;">July/August 2019</h3> | | <h3 style="font-family:'Righteous'; color:#2ecc71;">July/August 2019</h3> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Meeting with Prof. Oliver Kohlbacher</h3> | + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Meeting with Prof. Oliver Kohlbacher</h3> |
| <p> | | <p> |
− | To further refine our modelling approaches, we met with our long time supporter Prof. Dr. | + | To further refine our modelling approaches, we met with our long time supporter Prof. Dr. Oliver |
− | Oliver Kohlbacher of the Applied Bioinformatics Group at the University of Tübingen. During the | + | Kohlbacher of the Applied Bioinformatics Group at the University of Tübingen. During the meeting, |
− | meeting, the possibility of conducting a time-series RNA-Seq experiment to evaluate the efficacy
| + | the possibility of conducting a time-series RNA-Seq experiment to evaluate the efficacy of our |
− | of our kill-switch mechanism came up. Admittedly, we quickly discarded this idea due to a lack of
| + | kill-switch mechanism came up. Admittedly, we quickly discarded this idea due to a lack of time. |
− | time. Therefore, we discussed our RNA-Seq experimental design with respect to an E.
| + | Therefore, we discussed our RNA-Seq experimental design with respect to an <i>E. coli</i> Nissle |
− | Coli Nissle characterization, evaluation of the safety of our tool as well as the viability of our | + | characterization, evaluation of the safety of our tool as well as the viability of our |
− | regulation system under different conditions (<a href="https://2019.igem.org/Team:Tuebingen/Nissle" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Nissle","_self");'>Project/Nissle</a>). | + | regulation system under different conditions |
| + | (<a href="https://2019.igem.org/Team:Tuebingen/Nissle" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Nissle","_self");'>Project/Nissle</a>). |
| </p> | | </p> |
| </div> | | </div> |
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| | | |
| <h2 style="font-family:'Righteous'; color:#2ecc71;">August 2019</h2> | | <h2 style="font-family:'Righteous'; color:#2ecc71;">August 2019</h2> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">iGEM Amazonas Brasil (Manau) Nissle Collaboration</h3>
| + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">iGEM Amazonas Brasil (Manaus) Nissle Collaboration</h3> |
| <p> | | <p> |
| Team iGEM Amazonas (Brasil, Manau) contacted us via social media, since they wanted to work with | | Team iGEM Amazonas (Brasil, Manau) contacted us via social media, since they wanted to work with |
− | E. Coli Nissle 1917 in their project but needed further knowledge on the bacterium. Thus, | + | <i>E. coli</i> Nissle 1917 in their project but needed further knowledge on the bacterium. Thus, |
| we organised a skype call and sent them our protocols, as well as the data we acquired during our | | we organised a skype call and sent them our protocols, as well as the data we acquired during our |
| Nissle characterisation (<a href="https://2019.igem.org/Team:Tuebingen/Collaborations" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Collaborations","_self");'>People/Collaborations</a>). | | Nissle characterisation (<a href="https://2019.igem.org/Team:Tuebingen/Collaborations" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Collaborations","_self");'>People/Collaborations</a>). |
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| </div> | | </div> |
| | | |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Implementation of Collaboration with iGEM TAU Israel on SDGs and ethical evaluation</h3>
| + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Implementation of Collaboration with iGEM Tel Hai Migal on SDGs and ethical evaluation</h3> |
| <p> | | <p> |
− | iGEM TAU Israel has announced a collaboration on the SDGs on the collaboration proposals of iGEM. | + | iGEM Tel Hai Migal has announced a collaboration on the SDGs on the collaboration proposals of iGEM. |
| We really liked their idea of an Escape box | | We really liked their idea of an Escape box |
| (<a href="https://2019.igem.org/Team:Tuebingen/Collaborations" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Collaborations","_self");'>People/Collaborations</a>), since it is a really | | (<a href="https://2019.igem.org/Team:Tuebingen/Collaborations" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Collaborations","_self");'>People/Collaborations</a>), since it is a really |
| good example for the engagement of the SDGs within iGEM. Moreover, we discussed the ethics parts of | | good example for the engagement of the SDGs within iGEM. Moreover, we discussed the ethics parts of |
− | their project (<a href="https://2019.igem.org/Team:Tuebingen/Downloads" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Downloads","_self");'>Parts/Download</a>). To evaluate TAU’s | + | their project (<a href="https://2019.igem.org/Team:Tuebingen/Downloads" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Downloads","_self");'>Parts/Download</a>). To evaluate iGEM Tel Hai Migal’s |
| project, we contacted Stefan Gammel (<a href="https://2019.igem.org/Team:Tuebingen/Experts" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Experts","_self");'>Human Practices/Experts</a>). | | project, we contacted Stefan Gammel (<a href="https://2019.igem.org/Team:Tuebingen/Experts" onclick='window.open("https://2019.igem.org/Team:Tuebingen/Experts","_self");'>Human Practices/Experts</a>). |
| </p> | | </p> |
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| | | |
| <h2 style="font-family:'Righteous'; color:#2ecc71;">September 2019</h2> | | <h2 style="font-family:'Righteous'; color:#2ecc71;">September 2019</h2> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Move to the ZMBP research group of Prof. Klaus Harter</h3>
| + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Move to the ZMBP research group of Prof. Klaus Harter</h3> |
| <p> | | <p> |
| Since we do not have a laboratory which we can use permanently, we moved one building across the | | Since we do not have a laboratory which we can use permanently, we moved one building across the |
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| | | |
| | | |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Meeting with Dr. Rolf Hecker on Technology Transfer and IP</h3> | + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Meeting with Dr. Rolf Hecker on Technology Transfer and IP</h3> |
| <p> | | <p> |
| Since we were working on how an implementation of our project as a business would look like, | | Since we were working on how an implementation of our project as a business would look like, |
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| </div> | | </div> |
| | | |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Planning of RNA-Seq Experiments with Dr. Lisa Maier</h3> | + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Planning of RNA-Seq Experiments with Dr. Lisa Maier</h3> |
| <p> | | <p> |
| September 2019 - Planning of RNA-Seq Experiments with Dr. Lisa Maier of | | September 2019 - Planning of RNA-Seq Experiments with Dr. Lisa Maier of |
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| </div> | | </div> |
| | | |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Anaerobe E. Coli Nissle 1917 RNA preparation at the research group of Prof. Lars Angenent</h3>
| + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Anaerobe <i>E. coli</i> Nissle 1917 RNA preparation at the research group of Prof. Lars Angenent</h3> |
| <p> | | <p> |
| For our RNA-Seq experiments, we required anaerobic bacterial growth and sample preparation. Thus, the | | For our RNA-Seq experiments, we required anaerobic bacterial growth and sample preparation. Thus, the |
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| </div> | | </div> |
| | | |
− | <h3 style="font-family: Righteous; color: #2ecc71;">RNA-Seq with Angel Angelov of the NCCT</h3> | + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">RNA-Seq with Angel Angelov of the NCCT</h3> |
| <p> | | <p> |
| Due to the various conditions we wanted to test during our RNA-Seq experiments, we contacted Dr. | | Due to the various conditions we wanted to test during our RNA-Seq experiments, we contacted Dr. |
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| </div> | | </div> |
| | | |
− | <h3 style="font-family: Righteous; color: #2ecc71;">RNA-Seq with EMBL</h3>
| + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">RNA-Seq with EMBL</h3> |
| <p> | | <p> |
| For the second half of our samples, the RNA Sequencing experiments were conducted at the Genomics Core | | For the second half of our samples, the RNA Sequencing experiments were conducted at the Genomics Core |
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| </div> | | </div> |
| | | |
− | <h3 style="font-family:'Righteous'; color:#2ecc71;">14th September 2019</h3>
| + | <h3 style="font-family:'Righteous'; color:#2ecc71;">14th September 2019</h3> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">SDG Video Conference organised by iGEM TAS Taipei</h3>
| + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">SDG Video Conference organised by iGEM TAS Taipei</h3> |
| <p> | | <p> |
| iGEM TAS Taipei from Taiwan organised an online video conference on the SDGs, in which we happily took | | iGEM TAS Taipei from Taiwan organised an online video conference on the SDGs, in which we happily took |
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| | | |
| <h3 style="font-family:'Righteous'; color:#2ecc71;">September/October 2019</h3> | | <h3 style="font-family:'Righteous'; color:#2ecc71;">September/October 2019</h3> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Student Lab/Panel Discussion Experimenta Heilbronn</h3>
| + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Student Lab/Panel Discussion Experimenta Heilbronn</h3> |
| <p> | | <p> |
| The Experimenta is a science centre in Heilbronn, Germany, which aims at educating interested students | | The Experimenta is a science centre in Heilbronn, Germany, which aims at educating interested students |
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| | | |
| <h2 style="font-family:'Righteous'; color:#2ecc71;">October 2019</h2> | | <h2 style="font-family:'Righteous'; color:#2ecc71;">October 2019</h2> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Microbiome experts talk</h3> | + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Microbiome experts talk</h3> |
| <p> | | <p> |
| We were invited to present our project in front of the microbiome supergroup of the Max Planck | | We were invited to present our project in front of the microbiome supergroup of the Max Planck |
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| </div> | | </div> |
| | | |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Testing iGEM Stuttgart’s new medium and using it for our characterisation</h3> | + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Testing iGEM Stuttgart’s new medium and using it for our characterisation</h3> |
| <p> | | <p> |
| iGEM Stuttgart has developed a new bacterial medium, which we were happy to test in our Lab. | | iGEM Stuttgart has developed a new bacterial medium, which we were happy to test in our Lab. |
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| </div> | | </div> |
| | | |
− | <h3 style="font-family: Righteous; color: #2ecc71;"> Informative booth about the potential of GMOs in food and pharmaceutical industry</h3> | + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;"> Informative booth about the potential of GMOs in food and pharmaceutical industry</h3> |
| <p> | | <p> |
| Together with iGEM Dresden and the Institute for Innate Immunity Bonn | | Together with iGEM Dresden and the Institute for Innate Immunity Bonn |
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| | | |
| <h3 style="font-family:'Righteous'; color:#2ecc71;">17th October 2019</h3> | | <h3 style="font-family:'Righteous'; color:#2ecc71;">17th October 2019</h3> |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Prize for exceptional student engangement</h3> | + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Prize for exceptional student engangement</h3> |
| <p> | | <p> |
| Each year, the University of Tübingen honours student groups for exceptional student engagement. | | Each year, the University of Tübingen honours student groups for exceptional student engagement. |
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| </div> | | </div> |
| | | |
− | | + | <h3 style="font-family:'Righteous'; color:#2ecc71;">28th October 2019</h3> |
− | <h3 style="font-family:'Righteous'; color:#2ecc71;">28th October 2019</h3>
| + | |
− | <h3 style="font-family: Righteous; color: #2ecc71;">Supporters Pitch</h3>
| + | |
| <div class="row"> | | <div class="row"> |
| <div class="col-12"> | | <div class="col-12"> |
| + | |
| + | |
| + | <h3 style="font-family: Righteous; color: #2ecc71;">Supporters Pitch</h3> |
| <p> | | <p> |
| Since we received a lot of help during our iGEM experience - knowledge- and material-wise - we decided | | Since we received a lot of help during our iGEM experience - knowledge- and material-wise - we decided |
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| </script> | | </script> |
| | | |
− | <div class='container-fluid p-3' style="background-color: rgba(35, 35, 35, 0.4);"> | + | <div class='container-fluid p-3' style="background-color: #919191;"> |
− | <hr>
| + | <hr> |
− | <div class='row align-items-center'>
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− | <div class='col-6 col-md-2 sponsorLogo text-center'>
| + | <div class='col-6 col-md-2 sponsorLogo text-center'> |
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| + | <a href="https://www.stura-tuebingen.de/" target="_blank2"><img class="img-fluid" |
− | src="https://static.igem.org/mediawiki/2019/1/10/T--Tuebingen--stura_logo.png"
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− | <a href="https://www.embl.de/" target="_blank2"><img class="img-fluid" | + | <div class='col-6 col-md-2 sponsorLogo text-center'> |
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| + | <a href="https://www.dieter-schwarz-stiftung.de/homepage.html" target="_blank2"><img class="img-fluid" |
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| + | |
| <div class='col-6 col-md-2 sponsorLogo text-center'> | | <div class='col-6 col-md-2 sponsorLogo text-center'> |
− | <a href="https://www.medizin.uni-tuebingen.de/de/medizinische-fakultaet/forschung/core-facilities/ncct"
| + | <a href="https://www.medizin.uni-tuebingen.de/de/medizinische-fakultaet/forschung/core-facilities/ncct" |
− | target="_blank2"><img class="img-fluid"
| + | target="_blank2"><img class="img-fluid" |
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| + | |
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− | <div class='col-6 col-md-2 sponsorLogo text-center'> | + | |
− | <a href="https://www.kohlbacherlab.org" target="_blank2"><img class="img-fluid"
| + | <hr> |
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| + | <div class='col-4 col-md-2 col-xl-1 sponsorLogo text-center'> |
| + | <a href="https://www.lexogen.com/" target="_blank2"><img class="img-fluid" |
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| + | </div> |
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| + | <a href="https://www.zmbp.uni-tuebingen.de/zmbp.html" target="_blank2"><img class="img-fluid" |
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| + | <a href="http://s466755640.online.de/4bl/" target="_blank2"><img class="img-fluid" |
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| + | <a href="https://www.agilent.com/" target="_blank2"><img class="img-fluid" |
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| + | <a href="http://www.metabion.com/" target="_blank2"><img class="img-fluid" |
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| + | <a href="https://www.microsynth.ch/home-ch.html" target="_blank2"><img class="img-fluid" |
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− | <div class='col-6 col-md-2 sponsorLogo text-center'> | + | |
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| + | src="https://static.igem.org/mediawiki/2019/2/29/T--Tuebingen--neb_logo.png"></a> |
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| + | <a href="https://www.promega.de/en/" target="_blank2"><img class="img-fluid" |
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− | </div>
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− |
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