Difference between revisions of "Team:UESTC-China/Achievement"

Line 2: Line 2:
 
<html>
 
<html>
 
<body>
 
<body>
−
<style type="text/css">
+
<style type="text/css">
 
     ul.f_mh{
 
     ul.f_mh{
 
               position:fixed;
 
               position:fixed;
 
top:11em;
 
top:11em;
 
}
 
}
−
</style>
+
h2{
 +
font-weight: 600;
 +
}
 +
.mainbody a{
 +
color:#FF0004!important;
 +
}
 +
</style>
 
<div class="firstph">
 
<div class="firstph">
 
  <img alt="logo" src="https://static.igem.org/mediawiki/2019/f/f8/T--UESTC-China--achievement.jpg" style="width: 100%"> </div>
 
  <img alt="logo" src="https://static.igem.org/mediawiki/2019/f/f8/T--UESTC-China--achievement.jpg" style="width: 100%"> </div>
−
 
+
 
<div class="firstless" >
 
<div class="firstless" >
−
   <ul class="f_mh mya" style="display:none;margin-left:5px">
+
   <ul class="f_mh mya" style="display:none;margin-left:5px">
−
     <li class="active"><a href="#title_1">1.Energy crisise salhalsf salkhf aslhda</a></li>
+
     <li class="active"><a href="#title_1">Bronze</a></li>
−
     <li ><a href="#title_2">1.Energy crisise</a></li>
+
     <li ><a href="#title_2">Silver</a></li>
−
     <li ><a href="#title_3">1.Energy crisise</a></li>
+
     <li ><a href="#title_3">Gold</a></li>
−
     <li ><a href="#title_4">1.Energy crisise</a></li>
+
     <li ><a href="#title_4">Special Prizes</a></li>
 
   </ul>
 
   </ul>
−
   <a href="#"> <img  class="up" src="https://static.igem.org/mediawiki/2019/7/7d/T--UESTC-China--up.png" alt="logo" width="100%" > </a> </div>
+
   <a href="#"> <img  class="up" src="https://static.igem.org/mediawiki/2019/7/7d/T--UESTC-China--up.png" alt="logo" width="100%"> </a> </div>
  
−
<div class="container col-6">
+
<div class="container col-5">
 
   <div class="col-fmh" >
 
   <div class="col-fmh" >
−
    <div class="part">
+
<div class="mainbody">
−
      <div class="bigtitle" id="title_1" style="background-color: #b6caf2">
+
This year we meet all the requirements of medals standards, and we also expect to get five iGEM awards: Best Environment Project, Best Integrated Human Practices, Best Education & Public Engagement, and Best Model, Best Hardware. In this section, we clearly show each entries up to the standards. Please judge.
−
        <p>1. Energy crisis</p>
+
</div>
−
      </div>
+
<div class="part">
−
      <div class="mainbody" >
+
<div class="bigtitle">
−
        <p>With the continuous development and utilization of energy (Fig. 1), the earth's energy storage is crisis. Nothing has been found to be a perfect substitute to the energy consumption of coal, oil and other non-renewable energy resources. </p>
+
Bronze
−
        <p>A large number of energy consumption has seriously threatened the sustainable development of today's society [1]. When we keep looking for clean energy, a large amount of energy is being wasted because of our improper operations. So we have to reuse the often neglected wastes of our lives and turn them into the energy we consume.</p>
+
</div>
−
      </div>
+
−
      <div style="text-align: center"> <img alt="logo" src="#" class="piture"> </div>
+
<h2>1.Registration and Giant Jamboree Attendance</h2>
−
      <div class="words" >
+
−
        <p>Fig. 1  World primary energy consumption, 1992 to 2017 [1]. </p>
+
<div class="mainbody">We have registered for iGEM as UESTC-China on March 3h, 2019 and been accepted on March18th, 2019. We had a great summer and half of semester for our project. We have registered Giant Jamboree and planned for the travel.</div>
−
      </div>
+
−
    </div>
+
<h2>2.Competition Deliverables</h2>
−
    <div class="part">
+
<div class="mainbody">We have made Team Wiki, poster and prepared a wonderful presentation. We have accomplished and submitted the Judging Form and Safety Form on time.</div>
−
      <div class="bigtitle" id="title_2" style="background-color: #b6caf2">
+
<h2>3.Attributions</h2>
−
        <p>2. Straw is an ideal renewable energy resource </p>
+
<div class="mainbody">
−
      </div>
+
We have created a page on the team wiki with clear Attribution of each aspect of the project.
−
      <div class="mainbody" >
+
<a href="https://2019.igem.org/Team:UESTC-China/Attributions">Click here for more details about our Attributions.</a>
−
        <p>Straw is an agricultural byproduct of cereal plants. It makes up about half of the yield of cereal crops such as corn, barley, rice and wheat. Take corn as an example, according to FAO statistics, global corn production in 2016 was approximately 1060 million tons (Fig. 2) [2]. Every kilogram of harvested grain produces 1.2 kg of corn stalks, giving an estimate global corn straw production is 1272 million tons in 2016.</p>
+
</div>
−
      </div>
+
<h2>4.Project Inspiration and Description</h2>
−
      <div style="text-align: center;background-color: #F2F3F4"> <img alt="logo" src="#" class="piture"> </div>
+
<div class="mainbody">
−
      <div class="words" >
+
We recorded why we chose this project after giving up the idea at the beginning after a series of activities, and also recorded why we chose this project.
−
        <p>Fig. 2  Corn stalk production around the world, 2000 to 2016 [2]. </p>
+
<a href="https://2019.igem.org/Team:UESTC-China/Description">Click here for more details about our Project Inspiration and Description. </a>
−
      </div>
+
</div>
−
    </div>
+
<h2>5.Characterization</h2>
−
    <div class="part">
+
<div class="mainbody">
−
      <div class="bigtitle" id="title_3" style="background-color: #b6caf2">
+
We have added quantitative experimental characterization data to two existing Parts (BBa_K2556051 and BBa_K2556051) from the Registry of Standard Biological Parts and documented the characterization of these parts on the Main Page of that Part's Registry entry.
−
        <p>2. Straw is an ideal renewable energy resource </p>
+
<a href="https://2019.igem.org/Team:UESTC-China/Parts">Click here for more details about our part.</a>
−
      </div>
+
</div>
−
      <div class="mainbody" >
+
</div>
−
        <p>Straw is an agricultural byproduct of cereal plants. It makes up about half of the yield of cereal crops such as corn, barley, rice and wheat. Take corn as an example, according to FAO statistics, global corn production in 2016 was approximately 1060 million tons (Fig. 2) [2]. Every kilogram of harvested grain produces 1.2 kg of corn stalks, giving an estimate global corn straw production is 1272 million tons in 2016.</p>
+
<div class="part">
−
      </div>
+
<div class="bigtitle">
−
      <div style="text-align: center;background-color: #F2F3F4"> <img alt="logo" src="#" class="piture"> </div>
+
Silver
−
      <div class="words" >
+
</div>
−
        <p>Fig. 2  Corn stalk production around the world, 2000 to 2016 [2]. </p>
+
<h2>1.Validated Part</h2>
−
      </div>
+
<div class="mainbody">
−
    </div>
+
We have successfully validated three new BioBrick Parts (<a href="http://parts.igem.org/Part:BBa_K3034000">BBa_K3034000</a>and<a href="http://parts.igem.org/Part:BBa_K3034004">BBa_K3034004</a>and<a href="http://parts.igem.org/Part:BBa_K3034005">BBa_K3034005</a>)worked as expected through experiment. And we have documented the characterization of these parts on the Main Page of that Part's Registry entry.<a href="https://2019.igem.org/Team:UESTC-China/Parts">Click here for more details about our part.</a>
−
    <div class="part">
+
</div>
−
      <div class="bigtitle" id="title_4" style="background-color: #b6caf2">
+
<h2>2.Collaboration</h2>
−
        <p>2. Straw is an ideal renewable energy resource </p>
+
<div class="mainbody">
−
      </div>
+
This summer, we collaborated with five 2019 iGEM teams for a better progress in project of each other and hosted 2019 Southwestern iGEM Exchange Conference with UESTC-Software. <br>
−
      <div class="mainbody" >
+
We provided CAU_China with a plasmid and their simultaneous validation experiments. We discussed with SZU-China how to improve the expression of toxic protein and the feasibility of the project. We designed a questionnaire analysis method together with CSU_CHINA. ZJUT-China provided us with lysin. XMU-Chin was provided with a trial of our part of the last year. A total of five teams from Southwest China participated in the meetup we held.
−
        <p>Straw is an agricultural byproduct of cereal plants. It makes up about half of the yield of cereal crops such as corn, barley, rice and wheat. Take corn as an example, according to FAO statistics, global corn production in 2016 was approximately 1060 million tons (Fig. 2) [2]. Every kilogram of harvested grain produces 1.2 kg of corn stalks, giving an estimate global corn straw production is 1272 million tons in 2016.</p>
+
<a href="https://2019.igem.org/Team:UESTC-China/Collaborations">Click here for more details about our Collaborations.</a>
−
      </div>
+
</div>
−
      <div style="text-align: center;background-color: #F2F3F4"> <img alt="logo" src="#" class="piture"> </div>
+
<h2>3.Human Practices</h2>
−
      <div class="words" >
+
<div class="mainbody">
−
        <p>Fig. 2  Corn stalk production around the world, 2000 to 2016 [2]. </p>
+
We have thought carefully and creatively about whether our work is responsible and good for the world. We have documented on our team wiki how we have investigated these issues and engaged with our relevant communities, why we chose this approach, and what we have learned. Besides, our surveys followed scientifically valid methods which fulfilled this criteria.
−
      </div>
+
<a href="https://2019.igem.org/Team:UESTC-China/Human_Practices">Click here for more details about our Human Practices.</a>
−
      <div class="mainbody" >
+
</div>
−
        <p>Straw is an agricultural byproduct of cereal plants. It makes up about half of the yield of cereal crops such as corn, barley, rice and wheat. Take corn as an example, according to FAO statistics, global corn production in 2016 was approximately 1060 million tons (Fig. 2) [2]. Every kilogram of harvested grain produces 1.2 kg of corn stalks, giving an estimate global corn straw production is 1272 million tons in 2016.</p>
+
</div>
−
      </div>
+
<div class="part">
−
    </div>
+
<div class="bigtitle">
 +
Gold
 +
</div>
 +
<h2>1.Integrated Human Practices</h2>
 +
<div class="mainbody">In the process of our entire project, we draw on the waterfall model used in software engineering as our development model, and complete our project according to feasibility analysis, requirements analysis steps, project design ，and project realization. Human practice in the process is an indispensable tool for us throughout our entire process. In order to determine whether the project is feasible, we organized in the 5th Southwest China iGEM Exchange Conference to determine the technical feasibility and visited the 7th Water Supply Plant in Chengdu to determine the economic feasibility, understood whether the policy is feasible in the 4th Water Purification Plant. Through these activities, we decided to change from antibiotics in degraded water to recycling bins designed for expired drugs. To determine the users’ needs, we distributed more than 200 questionnaires for analysis and visited some chain pharmacies to determine the function and performance of the recycling bin.  
 +
<a href="https://2019.igem.org/Team:UESTC-China/Human_Practices">Click here for more details about our Integrated Human Practices.</a>
 +
</div>
 +
<h2>2.Improve a Previous Part</h2>
 +
<div class="mainbody">XXX</div>
 +
<h2>3.Model Your Project</h2>
 +
<div class="mainbody">
 +
1）We designed the experiment reasonably and used Plackett-Burman design combined with the experimental data to screen the external factors affecting the degradation of CIP of our engineered bacteria. We found the three most important influencing factors and obtained the degradation rate equation. Then we obtained the best degradation CIP conditions and corresponding degradation rates. And the effectiveness of the optimal conditions was verified by experiments.<br>
 +
2）We also established several differential equations for the quorum sensing process. Using this model, we predicted the yield of CrpP and got the curve of CrpP concentration varied with time. Then we found the relationship between the initial concentration of external AHL and the maximal yield of CrpP. So we found the best external concentration, which can help us find the best ratio of detection cells and processing cells, saving the total cost of the device.<br>
 +
3）In order to give the processing device a reasonable placement, we established a multi-objective programming model, which greatly improved the delivery probability of discarded antibiotics. We also obtained a specific device layout plan in a certain community by the model. Finally, we used the Analytic Hierarchy Process to establish an evaluation system for the layout scheme, so as to find the optimal layout scheme among many optimization schemes. This model provides a solution for device placement for human practice, saving project costs.
 +
<a href="https://2019.igem.org/Team:UESTC-China/Model">Click here for more details about our models.</a>
 +
</div>
 +
<h2>4.Demonstration of Your Work</h2>
 +
<div class="mainbody">xxxxxxxx</div>
 +
</div>
 +
 +
<div class="part">
 +
<div class="bigtitle">
 +
Special Prizes
 +
</div>
 +
<h2>1.Best Environment Projects</h2>
 +
<div class="mainbody">
 +
This year, UESTC-Chian designed an expired drug recycling bin, taking the most commonly used antibiotic ciprofloxacin as an example, using engineering E. coli to degrade expired drugs into environmentally friendly substances, and then using mathematical modeling to design points in the city to form an expired drug solution. According to the survey, 79% of households have expired drugs. In areas where waste sorting is carried out, expired drugs are classified as hazardous waste, and the treatment methods are still landfill and incineration, which still pollute the environment. In areas where waste separation is not implemented, expired drugs are treated together with household waste, and the damage to soil and water can not be ignored. The presence of expired drugs in sewage can lead to increased antibiotic resistance of many microbial strains in sewage. How to effectively treat expired drugs has become a problem that needs to be solved.
 +
<a href="https://2019.igem.org/Team:UESTC-China/Demonstrate">Click here for more details about our Demonstrates.</a>
 +
</div>
 +
<h2>2.Best Integrated Human Practices</h2>
 +
<div class="mainbody">
 +
In the process of our entire project, we draw on the waterfall model used in software engineering as our development model, and complete our project according to feasibility analysis, requirements analysis steps, project design ，and project realization. Human practice in the process is an indispensable tool for us throughout our entire process. In order to determine whether the project is feasible, we organized in the 5th Southwest China iGEM Exchange Conference to determine the technical feasibility and visited the 7th Water Supply Plant in Chengdu to determine the economic feasibility, understood whether the policy is feasible in the 4th Water Purification Plant. Through these activities, we decided to change from antibiotics in degraded water to recycling bins designed for expired drugs. To determine the users’ needs, we distributed more than 200 questionnaires for analysis and visited some chain pharmacies to determine the function and performance of the recycling bin.
 +
<a href="https://2019.igem.org/Team:UESTC-China/Human_Practices">Click here for more details about our Integrated Human Practices.</a>
 +
</div>
 +
<h2>3.Best Education & Public Engagement</h2>
 +
<div class="mainbody">
 +
xxx
 +
<a href="https://2019.igem.org/Team:UESTC-China/Public_Engagement">Click here for more details about our Education & Public Engagement.</a>
 +
</div>
 +
<h2>4.Best Hardware</h2>
 +
<div class="mainbody">
 +
xxx
 +
<a href="https://2019.igem.org/Team:UESTC-China/Hardware">Click here for more details about our Hardware.</a>
 +
</div>
 +
<h2>5.Best Model</h2>
 +
<div class="mainbody">
 +
xxx
 +
<a href="https://2019.igem.org/Team:UESTC-China/Model">Click here for more details about our Model.</a>
 +
</div>
 +
</div>
 
   </div>
 
   </div>
 
</div>
 
</div>
Line 81: Line 136:
 
var oli=$('.f_mh li');
 
var oli=$('.f_mh li');
 
$(window).scroll(function(){
 
$(window).scroll(function(){
−
$(".part").each(function(){
+
$(".bigtitle").each(function(index){
 
var _target=parseInt($(this).offset().top-$(window).scrollTop()-_line);
 
var _target=parseInt($(this).offset().top-$(window).scrollTop()-_line);
−
var _i=$(this).index()
+
var _i=index;
 
if (_target<=0) {
 
if (_target<=0) {
 
oli.removeClass('active');
 
oli.removeClass('active');
Line 103: Line 158:
 
});
 
});
 
</script>
 
</script>
−
 
−
 
 
<script>
 
<script>
−
$(document).ready(function() {  
+
$(function(){
−
+
$('.up').click(function() {
 +
$('html, body').stop().animate({
 +
            scrollTop: '0'
 +
        }, 1000);
 +
      });
 +
})
 +
</script>
 +
<script>
 +
$(function() {
 
         $(window).scroll(function() {
 
         $(window).scroll(function() {
 
             if ($(window).scrollTop() > 400) {
 
             if ($(window).scrollTop() > 400) {

Revision as of 06:50, 6 October 2019

description

0% 完成
logo
logo
This year we meet all the requirements of medals standards, and we also expect to get five iGEM awards: Best Environment Project, Best Integrated Human Practices, Best Education & Public Engagement, and Best Model, Best Hardware. In this section, we clearly show each entries up to the standards. Please judge.
Bronze

1.Registration and Giant Jamboree Attendance

We have registered for iGEM as UESTC-China on March 3h, 2019 and been accepted on March18th, 2019. We had a great summer and half of semester for our project. We have registered Giant Jamboree and planned for the travel.

2.Competition Deliverables

We have made Team Wiki, poster and prepared a wonderful presentation. We have accomplished and submitted the Judging Form and Safety Form on time.

3.Attributions

We have created a page on the team wiki with clear Attribution of each aspect of the project. Click here for more details about our Attributions.

4.Project Inspiration and Description

We recorded why we chose this project after giving up the idea at the beginning after a series of activities, and also recorded why we chose this project. Click here for more details about our Project Inspiration and Description.

5.Characterization

We have added quantitative experimental characterization data to two existing Parts (BBa_K2556051 and BBa_K2556051) from the Registry of Standard Biological Parts and documented the characterization of these parts on the Main Page of that Part's Registry entry. Click here for more details about our part.
Silver

1.Validated Part

We have successfully validated three new BioBrick Parts (BBa_K3034000andBBa_K3034004andBBa_K3034005)worked as expected through experiment. And we have documented the characterization of these parts on the Main Page of that Part's Registry entry.Click here for more details about our part.

2.Collaboration

This summer, we collaborated with five 2019 iGEM teams for a better progress in project of each other and hosted 2019 Southwestern iGEM Exchange Conference with UESTC-Software.
We provided CAU_China with a plasmid and their simultaneous validation experiments. We discussed with SZU-China how to improve the expression of toxic protein and the feasibility of the project. We designed a questionnaire analysis method together with CSU_CHINA. ZJUT-China provided us with lysin. XMU-Chin was provided with a trial of our part of the last year. A total of five teams from Southwest China participated in the meetup we held. Click here for more details about our Collaborations.

3.Human Practices

We have thought carefully and creatively about whether our work is responsible and good for the world. We have documented on our team wiki how we have investigated these issues and engaged with our relevant communities, why we chose this approach, and what we have learned. Besides, our surveys followed scientifically valid methods which fulfilled this criteria. Click here for more details about our Human Practices.
Gold

1.Integrated Human Practices

In the process of our entire project, we draw on the waterfall model used in software engineering as our development model, and complete our project according to feasibility analysis, requirements analysis steps, project design ，and project realization. Human practice in the process is an indispensable tool for us throughout our entire process. In order to determine whether the project is feasible, we organized in the 5th Southwest China iGEM Exchange Conference to determine the technical feasibility and visited the 7th Water Supply Plant in Chengdu to determine the economic feasibility, understood whether the policy is feasible in the 4th Water Purification Plant. Through these activities, we decided to change from antibiotics in degraded water to recycling bins designed for expired drugs. To determine the users’ needs, we distributed more than 200 questionnaires for analysis and visited some chain pharmacies to determine the function and performance of the recycling bin. Click here for more details about our Integrated Human Practices.

2.Improve a Previous Part

XXX

3.Model Your Project

1）We designed the experiment reasonably and used Plackett-Burman design combined with the experimental data to screen the external factors affecting the degradation of CIP of our engineered bacteria. We found the three most important influencing factors and obtained the degradation rate equation. Then we obtained the best degradation CIP conditions and corresponding degradation rates. And the effectiveness of the optimal conditions was verified by experiments.
2）We also established several differential equations for the quorum sensing process. Using this model, we predicted the yield of CrpP and got the curve of CrpP concentration varied with time. Then we found the relationship between the initial concentration of external AHL and the maximal yield of CrpP. So we found the best external concentration, which can help us find the best ratio of detection cells and processing cells, saving the total cost of the device.
3）In order to give the processing device a reasonable placement, we established a multi-objective programming model, which greatly improved the delivery probability of discarded antibiotics. We also obtained a specific device layout plan in a certain community by the model. Finally, we used the Analytic Hierarchy Process to establish an evaluation system for the layout scheme, so as to find the optimal layout scheme among many optimization schemes. This model provides a solution for device placement for human practice, saving project costs. Click here for more details about our models.

4.Demonstration of Your Work

xxxxxxxx
Special Prizes

1.Best Environment Projects

This year, UESTC-Chian designed an expired drug recycling bin, taking the most commonly used antibiotic ciprofloxacin as an example, using engineering E. coli to degrade expired drugs into environmentally friendly substances, and then using mathematical modeling to design points in the city to form an expired drug solution. According to the survey, 79% of households have expired drugs. In areas where waste sorting is carried out, expired drugs are classified as hazardous waste, and the treatment methods are still landfill and incineration, which still pollute the environment. In areas where waste separation is not implemented, expired drugs are treated together with household waste, and the damage to soil and water can not be ignored. The presence of expired drugs in sewage can lead to increased antibiotic resistance of many microbial strains in sewage. How to effectively treat expired drugs has become a problem that needs to be solved. Click here for more details about our Demonstrates.

2.Best Integrated Human Practices

In the process of our entire project, we draw on the waterfall model used in software engineering as our development model, and complete our project according to feasibility analysis, requirements analysis steps, project design ，and project realization. Human practice in the process is an indispensable tool for us throughout our entire process. In order to determine whether the project is feasible, we organized in the 5th Southwest China iGEM Exchange Conference to determine the technical feasibility and visited the 7th Water Supply Plant in Chengdu to determine the economic feasibility, understood whether the policy is feasible in the 4th Water Purification Plant. Through these activities, we decided to change from antibiotics in degraded water to recycling bins designed for expired drugs. To determine the users’ needs, we distributed more than 200 questionnaires for analysis and visited some chain pharmacies to determine the function and performance of the recycling bin. Click here for more details about our Integrated Human Practices.

3.Best Education & Public Engagement

xxx Click here for more details about our Education & Public Engagement.

4.Best Hardware

xxx Click here for more details about our Hardware.

5.Best Model

xxx Click here for more details about our Model.
Copyright © 2019 iGEM UESTC-China
logo