1.Registration and Giant Jamboree Attendance
4.Project Inspiration and Description
We have successfully validated three new BioBrick Parts(BBa_K3034000 and BBa_K3034004 and BBa_K3034005)worked as expected through experiment. And we have documented the characterization of these parts on the Main Page of that Part's Registry entry. Click here for more details about our part.
We provided CAU_China with a plasmid and their simultaneous validation experiments. We discussed with SZU-China how to improve the expression of toxic protein and the feasibility of the project. We designed a questionnaire analysis method together with CSU_CHINA. ZJUT-China provided us with lysin. XMU-China was provided with a trial of our part of the last year. A total of five teams from Southwest China participated in the meetup we held. Click here for more details about our Collaborations.
1.Integrated Human Practices
2.Improve a Previous Part
3.Model Your Project
2）We also established several differential equations for the quorum sensing process. Using this model, we predicted the yield of CrpP and got the curve of CrpP concentration varied with time. Then we found the relationship between the initial concentration of external AHL and the maximal yield of CrpP. So we found the best external concentration, which can help us find the best ratio of detection cells and processing cells, saving the total cost of the device.
3）In order to give the treatment device a reasonable placement, we established a multi-objective programming model, which greatly improved the delivery probability of discarded antibiotics. We also obtained a specific device layout plan in a certain community by the model. Finally, we used the Analytic Hierarchy Process to establish an evaluation system for the layout scheme, so as to find the optimal layout scheme among many optimization schemes. This model provides a solution for device placement for human practice, saving project costs.
Click here for more details about our models.
4.Demonstration of Your Work
1.Best Environment Projects
This year, UESTC-China designed an expired drug recycling bin, taking the most commonly used antibiotic ciprofloxacin as an example, using engineering E.coli to degrade expired drugs into environmentally friendly substances, and then using mathematical modeling to design points in the city to form an expired drug solution. Click here for more details about our Demonstrates.
2.Best Integrated Human Practices
3.Best Education & Public Engagement
Our educational activities take place in both the elderly and children. In the process of investigating expired drugs, we found that the elderly are the people who take the most expired drugs, so we have made scientific popularization through square dance in China's most popular entertainment activities. We adapted the lyrics of the square dance songs, hoping that the elderly can learn about expired drugs during the dance process. Together with UESTC software, we brought a synthetic biology adventure to children during Children's Day. We performed our project in the form of a stage play, vividly explained the synthetic biology to the children, and also inspired children to imagine the application of synthetic biology through lectures. Planting synthetic biology seeds in the hearts of children Click here for more details about our Education & Public Engagement.