Team:IIT-Madras/LP2.0
The Language Project 2.0!
1. INTRODUCTION TO SYNTHETIC BIOLOGY:
“The potential for synthetic biology and biotechnology is vast; we all have an opportunity to create the future together.”
This video lays out a fascinating view into the field of science that involves redesigning organisms for useful purposes by engineering them to have new abilities. Synthetic biology focuses on creating technologies for designing and building biological organisms, involving biologists, engineers, software developers, and others to collaborate on finding ways to understand how genetic parts work together, and then combining them to produce useful applications.
2. DNA & RNA:
Genes. That’s what decides what we become. But do you know what they are made of? DNA!!! And they provide the recipe for RNA!!!
In this video, we provide an elemental account on DNA, considered as the blueprint of the cell and RNA, known as the DNA photocopy of the cell. DNA is responsible for storing and transferring genetic information while mRNA directly codes for amino acids and acts as a messenger between DNA and ribosomes to make proteins.
3. PROTEINS:
The expressed proteins constitute your phenotype. But what are these proteins?
This video elaborates one of the complex molecules that play many critical roles in cells and are required for the structure, function, and regulation of biological systems. Proteins are macromolecules formed by structural units called amino acids. These function to transport materials across membranes, catalyze chemical reactions, support the movement of materials within a cell, and even drive movement of the entire cell.
4. REPLICATION AND TRANSCRIPTION:
Ever wondered how these genetic materials are produced? Well, DNA self replicates in a semi-conservative manner whereas, RNAs are generated from DNA through a process called Transcription.
This video discusses the processes that transfer genetic information from the nucleus to the ribosomes, that is important for the proper regulation of gene expression, growth and division of cells. DNA replication is the process by which a double-stranded DNA molecule is copied to produce two identical DNA molecules while Transcription is the process by which the information in a strand of DNA is copied into a new molecule of messenger RNA (mRNA).
5. CENTRAL DOGMA AND TRANSLATION:
DNA → RNA → Protein. And that’s the Central Dogma of Molecular Biology, in fact, of life!
In this video, we briefly explain Central Dogma, that reveals the basic framework for the genetic information flow. The central dogma of molecular biology describes the two-step process, transcription and translation, by which the information in genes flows into proteins. The mRNA, produced after transcription, is translated into protein in the ribosomes within the cell.
6. GENETIC CODE AND MUTATIONS:
Everybody needs a rulebook. We all do and so does DNA and RNA! This is called ‘The Genetic Code’. It dictates the translation of genetic instructions into proteins and decides how an organism will develop.
The video for ‘Genetic Code and Mutations’, gives a brief overview of how these set of rules govern living organisms. To get a better understanding of it, we need to know the features of The Genetic Code and what happens to the organism if there are mutations in the DNA. We have also discussed a specific example of point mutation and its effects.
7. EVOLUTION:
“Nothing in Biology makes sense except in the light of Evolution” - Theodosius Dobzhansky.
In this video, we provide a simple yet informative outlook into one of the seemingly controversial topics around, ‘Evolution’. Evolution has huge relevance to our world and current issues, paving a way to predict the future by understanding the past. The theory of evolution by natural selection is the process by which organisms change over time as a result of changes in heritable physical or behavioural traits. And we, dwell on them… a little!
HERE'S WHAT'S NEW:
COLLABORATIONS:
Introduction to Synthetic Biology
Dutch
Japanese
Konkani
Lithuanian
Portuguese
Turkish
Central Dogma and Translation
French
Spanish
Dutch
Japanese
Konkani
Lithuanian
Portuguese
Turkish
Central Dogma and Translation
French
Spanish
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Department of Biotechnology, IIT Madras.
Chennai 36, India.
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