Difference between revisions of "Team:UM Macau"

 
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{{UM_Macau}}  
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{{UM_Macau/wikistripdown}}{{UM_Macau/Bootstrap}}{{UM_Macau/Navbar}}
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{{UM_Macau/bootstrap}}
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<html>
 
<html>
  
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<div>
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<head>
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<h1> Welcome to iGEM UM_Macau </h1>
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<div>
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  <meta name="viewport" content="width=device-width, initial-scale=1">
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<h3> Abstract </h3>
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  <link href="https://fonts.googleapis.com/css?family=Poppins:300,300i,400,700,800&display=swap" rel="stylesheet">
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<p>The project SANCE is a 14-months project starting from August 2018 and ending in October 2019. The project demonstrates and proves the concept of a controllable nanoparticle/microparticle collector microorganism, through which, we would able to solve the current issue of suspended solids exceeding standards in Macau sewage treatment process and eventually lead to cheaper and more effective wastewater treatment technique. The project also plan to largely engage in public society by holding diverse outreach activities including local wastewater treatment plant visiting,  social survey and interview, university workshop and summer camp engagement. Through this project, we aim to achieve a more efficient sewage technique and hereby enhance the awareness of Macau residents in water source protection. </p>
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<style>
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html,body{
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img {vertical-align: middle;}
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.video{
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box-shadow: 0 0 6px #fff;
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#inspiration{
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#solution{
 +
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height: 100vh;
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display: table;
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height: 100vh;
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position: relative;
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width: 100%;
 +
background-size: cover;
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/*'More About Us' styling*/
 +
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 +
display: table;
 +
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 +
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 +
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 +
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 +
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 +
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 +
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 +
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 +
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 +
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/*footer styling*/
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footer{
 +
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background-color:#131111;
 +
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 +
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 +
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 +
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 +
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 +
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 +
 
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footer h4{
 +
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 +
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 +
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 +
 
 +
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 +
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 +
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 +
footer h6{
 +
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.social{
 +
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.social:hover{
 +
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.sponsor{
 +
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 +
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 +
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@media (max-width: 768px) {
 +
.line {
 +
font-size: 130%;
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 +
</style>
 +
</head>
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<body>
 +
<div id="home">
 +
<div class="landpage container-fluid">
 +
<div class="row">
 +
<div class="col-sm-12">
 +
<img class="img-fluid" src="https://static.igem.org/mediawiki/2019/d/d5/T--UM_Macau--homepicSANCE.png" style="width:70%">
 +
</div>
 +
</div>
 +
 
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<div>
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<h2 class="line anim-typewriter">Self-Activating Nanoparticle Collector E.coli</h2>
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</div>
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 +
<div class="arrow">
 +
<a href="#medal"><img class="img-fluid" src="https://static.igem.org/mediawiki/2019/3/36/T--UM_Macau--homepicdownarrow.png"></a>
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</div>
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</div>
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<div>
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</div>
 
</div>
  
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<div>
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<h3> Introduction </h3>
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<p>With the entrance into 21st century, enormous new techniques and innovations are expanding rapidly, people’s demands of high-quality life are rising along with. Industrial water consumption increased, so as domestic water consumption. In the decade between 2008 to 2018, the total water consumption in Macau increased more than 20 million cubic meters. However, according to the official statistics from DSEC Macau, the daily average of total suspended solids in the waste water treated at the WWTP in Coloane exceeded the limit value by 276.7% in 2017. A new advanced solid-particle collection technique is in an urgent need. </p>
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</div>
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<p>Our team, as a participant in the 2019 International Genetically Modified Machinery (iGEM) competition, aim to apply the synthetic biology into society by engineering a controllable nanoparticle/microparticle collector microorganism via bacteria aggregation in the process of wastewater treatment. Additionally, via a magnetic field, we would achieve a goal of microorganism immobilization to eventually collect the nano- or micro- particles in wastewater. Its capabilities in collecting nanoparticles will be applied to remove possible pollutants, particularly those undegradable pollutants, such as heavy metal mercury, phosphate, total nitrogen, ammonia nitrogen, and organic compounds. The success of our project would provide a cheap and renewable organism that we can use to clean up particles at the nano- or micro- levels. We are targeting at particle-free water release, and treated water can be educed into natural water or used for domestic supply after post-treatment.</p>
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</div>
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</div>  
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 +
<div id="medal" class="padding">
 +
<div class="container text-center">
 +
<div class="row">
 +
<div class="col-sm-12">
 +
<h1 class="title"><u>Achievement</u></h1>
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<br>
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<br>
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<h1 class="title" style="font-size: 2.5rem">Gold Medal</h1>
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<h1 class="title" style="font-size: 2.5rem">Nomination in Best Part Collection</h1>
 +
</div>
 +
</div>
 
 
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<div>
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</div>
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<p><b>Our project is inspired</b> by a literature, “Preparation of Sticky Escherichia coli through Surface Display of an Adhesive Catecholamine Moiety” published by a Korean research team in 2014. Based on the idea of engineering a bacteria with sticky feature on its cell surface, we would like to focus on the structure and characteristics of the sticky domain of the engineered E. coli and enhance its effectiveness and efficiency in capturing nanoparticles by transforming the E.coli with a variety of plasmid constructs. With the improved version of E. coli, it is expected to be capable in capturing those pollutants mentioned above which are currently a noteworthy issue in wastewater treatment. Our project is noticeable because the advanced sticky feature on E. coli is expected to be capable in binding on almost all surface materials. </p>
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</div>  
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</div>  
+
<div class="slideshow-container">
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<div class="mySlides fade">
 +
  <img src="https://static.igem.org/mediawiki/2019/c/c5/T--UM_Macau--m2.png" style="width:100%">
 +
</div>
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 +
<div class="mySlides fade">
 +
  <img src="https://static.igem.org/mediawiki/2019/b/bc/T--UM_Macau--m11.png" style="width:100%">
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</div>
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 +
<div class="mySlides fade">
 +
  <img src="https://static.igem.org/mediawiki/2019/7/72/T--UM_Macau--m3.png" style="width:100%">
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</div>
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 +
<div class="mySlides fade">
 +
  <img src="https://static.igem.org/mediawiki/2019/b/b6/T--UM_Macau--m5.png" style="width:100%">
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 +
<div class="mySlides fade">
 +
  <img src="https://static.igem.org/mediawiki/2019/e/ee/T--UM_Macau--m4.png" style="width:100%">
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</div>
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<div class="mySlides fade">
 +
  <img src="https://static.igem.org/mediawiki/2019/3/31/T--UM_Macau--m6.png" style="width:100%">
 +
</div>
 +
 
 +
<a class="prev" onclick="plusSlides(-1)">&#10094;</a>
 +
<a class="next" onclick="plusSlides(1)">&#10095;</a>
 +
 
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</div>
 +
<br>
 +
 
 +
<div style="text-align:center">
 +
  <span class="dot" onclick="currentSlide(1)"></span>
 +
  <span class="dot" onclick="currentSlide(2)"></span>
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  <span class="dot" onclick="currentSlide(3)"></span>
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  <span class="dot" onclick="currentSlide(4)"></span>
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<div class="padding" id="abstract">
 +
<div class="container">
 +
<div>
 +
<h1 class="title">Abstract</h1>
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</div>
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<p style="font-size: 1.3rem; text-align: justify">Our project SANCE will be targeting on the nanoparticle pollution, an unneglectable issue facing by coast-like cities including Macau. We aim to engineer a controllable nanoparticle collector microorganism. We hypothesize that our modified E.coli bacteria expressing the adhesive fusion protein on its cell surface that would be able to collect nanoparticle targets, through which, we will be able to help to solve the current issue of excessive suspended solids in Macau wastewater treatment process. Through this project, we aim to achieve a more efficient nanoparticles elimination technique and thereby enhance the awareness of Macau residents in water source protection.</p>
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<p>With the emergence and rapid development of nanotechnology, nanoparticles have been widely used in many field that closely related to our daily life. However, nanoparticles could bring severe adverse effects to ecosystem and human health. </p>
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<p>Our project is inspired by the capability of a sticky protein named Mefp-5 expressed on the foot of mussel which make it able to attach on almost all surface. We take the 'Special sticky characteristic' as the main feature in our project to solve the problem.</p>
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<p>Our team was motivated to establish an effective nanoparticles removing model named SANCE. Its capability in collecting nanoparticles would potentially be applied in wastewater treatment plant to remove harmful nanopollutants.
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Latest revision as of 07:16, 19 December 2019


Self-Activating Nanoparticle Collector E.coli

Achievement



Gold Medal

Nomination in Best Part Collection


Abstract

Our project SANCE will be targeting on the nanoparticle pollution, an unneglectable issue facing by coast-like cities including Macau. We aim to engineer a controllable nanoparticle collector microorganism. We hypothesize that our modified E.coli bacteria expressing the adhesive fusion protein on its cell surface that would be able to collect nanoparticle targets, through which, we will be able to help to solve the current issue of excessive suspended solids in Macau wastewater treatment process. Through this project, we aim to achieve a more efficient nanoparticles elimination technique and thereby enhance the awareness of Macau residents in water source protection.

Current Problem: Nanoparticle Pollution

With the emergence and rapid development of nanotechnology, nanoparticles have been widely used in many field that closely related to our daily life. However, nanoparticles could bring severe adverse effects to ecosystem and human health.

Project Inspiration

Our project is inspired by the capability of a sticky protein named Mefp-5 expressed on the foot of mussel which make it able to attach on almost all surface. We take the 'Special sticky characteristic' as the main feature in our project to solve the problem.

Our Solution

Our team was motivated to establish an effective nanoparticles removing model named SANCE. Its capability in collecting nanoparticles would potentially be applied in wastewater treatment plant to remove harmful nanopollutants.

More About Us



CONTACT US

umac.igem@gmail.com

FOLLOW US

iGEM 2019 UM_Macau