Introduction
This part collection consists of 3 designed glucose sensing promoters 3xGSP, 6XGSP and 9xGSP. These promoters are composited of set amounts of CHoRE, binding site of double dephosphorylated CHREBP that functions as a transcription enhancer. As CHREBP dephosphorylation is induced by glucose, it allows the composite promoter to response to extracellular glucose concentration and regulate the promoter intensity, which may make a promising controllable "smart" promoter.
Figure 1: The structure of the three parts.
BBa_K3064005 | 3XGlucose Sensing Promter |
BBa_K3064011 | 6XGlucose Sensing Promoter |
BBa_K3064012 | 9XGlucose Sensing Promoter |