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to surface-bound molecules. We placed them in our different devices, giving them different roles, and | to surface-bound molecules. We placed them in our different devices, giving them different roles, and | ||
compared their function to determine the most suitable one.</p> | compared their function to determine the most suitable one.</p> | ||
− | <img style="width: 75%;" src=" | + | <img style="width: 75%;" src="https://static.igem.org/mediawiki/2019/5/56/T--SMMU-China--partcollection_1.png" |
alt="smmu_demonstrate_1" style="margin: 0px;"> | alt="smmu_demonstrate_1" style="margin: 0px;"> | ||
− | <img style="width: 75%;" src=" | + | <img style="width: 75%;" src="https://static.igem.org/mediawiki/2019/b/bc/T--SMMU-China--partcollection_2.png" |
alt="smmu_demonstrate_1" style="margin: 10px 0px;"> | alt="smmu_demonstrate_1" style="margin: 10px 0px;"> | ||
<center>Figure 1. The structure and mechanism of synthetic receptors we chose. a. chimeric antigen receptor | <center>Figure 1. The structure and mechanism of synthetic receptors we chose. a. chimeric antigen receptor |
Revision as of 11:58, 21 October 2019
1.Synthetic receptors
OverView
Transmembrane receptors can continuously monitor the extracellular milieu, and transduce specific extracellular signals into intracellular responses. Binding of ligands that match the receptors triggers intracellular signaling cascades and ultimately induces transcriptional changes[1]. We found some latest receptors, with some of them sensing and responding to soluble molecules while others sensing and responding to surface-bound molecules. We placed them in our different devices, giving them different roles, and compared their function to determine the most suitable one.
DEMO PART 2
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DEMO PART 3
Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season!