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− | <link rel="stylesheet" href="https://2019.igem.org/wiki/index.php?title=Template:SMMU-China/CSS_main&action=raw&ctype=text/css" /> | + | <link rel="stylesheet" |
+ | href="https://2019.igem.org/wiki/index.php?title=Template:SMMU-China/CSS_main&action=raw&ctype=text/css"/> | ||
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− | + | <div class="big_framework"> | |
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− | + | <div class="index-nav-frame-logo"> | |
− | + | <img src="https://static.igem.org/mediawiki/2019/f/f5/T--SMMU-China--wukong_logo.png" alt="Wukong"> | |
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− | + | <a href="https://2019.igem.org/Team:SMMU-China">Home</a> | |
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− | + | PROJECT | |
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− | + | <a href="https://2019.igem.org/Team:SMMU-China/Description">Description</a> | |
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− | + | HUMAN PRACTICES | |
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− | + | <a href="https://2019.igem.org/Team:SMMU-China/Human_Practices">Human Practices</a> | |
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− | + | Team | |
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− | + | <a href="https://2019.igem.org/Team:SMMU-China/Team">Team</a> | |
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− | + | <a href="https://2019.igem.org/Team:SMMU-China/Attributions">Attributions</a> | |
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− | + | ||
− | + | <div class="blank_framework"></div> | |
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− | + | <img src="https://static.igem.org/mediawiki/2019/8/82/T--SMMU-China--page_banner_default.jpg" | |
− | + | alt="page_banner_default"> | |
+ | </div> | ||
− | + | <div class="page_big_title_box"> | |
− | + | <div class="page_big_title">Part Collection</div> | |
− | + | <div class="page_big_subtitle">This is a descriptive paragraph.</div> | |
− | + | </div> | |
− | + | <div class="medium_framework"> | |
− | + | <h1><b>1.Synthetic receptors</b></h1> | |
− | + | <h1 style="text-align: left">OverView</h1> | |
− | + | <p>Transmembrane receptors can continuously monitor the extracellular milieu, and transduce specific | |
+ | extracellular signals into intracellular responses. Binding of ligands that match the receptors triggers | ||
+ | intracellular signaling cascades and ultimately induces transcriptional changes<sup>[1]</sup>. We found some | ||
+ | latest | ||
+ | receptors, with some of them sensing and responding to soluble molecules while others sensing and responding | ||
+ | to surface-bound molecules. We placed them in our different devices, giving them different roles, and | ||
+ | compared their function to determine the most suitable one.</p> | ||
+ | <img style="width: 75%;" src="https://static.igem.org/mediawiki/2019/5/53/T--SMMU-China--parts_basicparts_1.png" | ||
+ | alt="smmu_demonstrate_1" style="margin: 0px;"> | ||
+ | <img style="width: 75%;" src="https://static.igem.org/mediawiki/2019/5/53/T--SMMU-China--parts_basicparts_1.png" | ||
+ | alt="smmu_demonstrate_1" style="margin: 10px 0px;"> | ||
+ | <center>Figure 1. The structure and mechanism of synthetic receptors we chose. a. chimeric antigen receptor | ||
+ | (CAR) b. SynNotch c. Modular extracellular sensor architecture (MESA) d. Generalized extracellular molecule | ||
+ | sensor (GEMS) | ||
+ | </center> | ||
+ | </div> | ||
− | + | <div class="medium_framework"> | |
− | + | <h1> DEMO PART 2 </h1> | |
− | + | <p>Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you | |
− | + | are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! | |
+ | Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you | ||
+ | are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! | ||
+ | Your team has been approved and you are ready to start the iGEM season! </p> | ||
+ | </div> | ||
− | + | <div class="medium_framework"> | |
− | + | <h1> DEMO PART 3 </h1> | |
− | + | <p>Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you | |
− | + | are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! | |
+ | Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you | ||
+ | are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! | ||
+ | Your team has been approved and you are ready to start the iGEM season! </p> | ||
+ | </div> | ||
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− | + | <div class="footer_title">Contact Us</div> | |
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− | + | E-Mail: igem-smmu@smmu.edu.cn<br> | |
− | + | Phone: +86 021-81870925 | |
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− | + | © 2019. SMMU. All rights reserved. | |
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Revision as of 11:51, 21 October 2019
1.Synthetic receptors
OverView
Transmembrane receptors can continuously monitor the extracellular milieu, and transduce specific extracellular signals into intracellular responses. Binding of ligands that match the receptors triggers intracellular signaling cascades and ultimately induces transcriptional changes[1]. We found some latest receptors, with some of them sensing and responding to soluble molecules while others sensing and responding to surface-bound molecules. We placed them in our different devices, giving them different roles, and compared their function to determine the most suitable one.
DEMO PART 2
Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season!
DEMO PART 3
Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season! Your team has been approved and you are ready to start the iGEM season!