Difference between revisions of "Team:USP-Brazil"

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Genetic Switch for Bioproduction
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                        Genetic Switch for Bioproduction
 
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Revision as of 22:31, 19 October 2019



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Light is a fine, precise inductor, as the specificity of the signal is in the emissor, the wavelength and intensity, and in the receptor, in our case, a protein, that recognize a specific wavelength ortogonali. Besides that, light can be activated instantaneously, simply by turning on it’s source. To stop the induction, it’s not necessary to change the culture media or wash the culture, a process that can make some bioproduction impossible. Using light opens new possibilities for this industry.

We wanted to make bioproduction an optimized process, and in our research we learn that a switch will be useful to regulate expression of two different states. For example, to produce two different compounds switching back and forward between the two, to get to an optimum. Another example of this strategy is the use of switch to alternate between growth of the bacteria culture and production of the compound of interest. This allows testing different combinations of time of growth and production to get to a maximum yield like shown in this case.