The SZPT-CHINA team is a new team of 14 members that has just been formed this year. Each of them is passionate about the iGEM competition. However, It is hard to complete the iGEM competition, for we are all new and have only a rough understanding of iGEM. The rules of the competition, human practices, schedule, wiki editing... all confuse us. Fortunately, the SZU-China team is a team with extensive experience in Shenzhen and has achieved considerable awards in the past years. Therefore, we asked them for help and established collaborations with them.
They have greatly assisted in the completion of our project, whether in human practices, scheduling, or wiki editing. Without their constant guidance, we will not be able to complete all the requirements.
In addition, we have also conducted in-depth cooperation. With the help of the SZU-China team, we successfully held a lecture on synthetic biology for more than 366 people. In addition the SZU-China team developed a applet(GREEN Hunter) for locating Mikania micrantha this year, which is needed to collect the distribution of Mikania micrantha in different regions. We tried our best to collect the distribution of Mikania micrantha near Shenzhen Polytechnic and to remove it.
The UCAS-China team tried to build a biosafety universal platform for microbial therapy with high-efficiency temperature-sensitive switches. After in-depth communication, we learned that they only validated it in their E. coli system currently. To further validate the versatility of their platform, we validated the cold-inducible genetic switch plasmids including TEVts and TF-GFP from them in the lactic acid bacteria system. Unfortunately, the experiment did not succeed, but we also pointed out some problems in the system in lactic acid bacteria, such as codon preference. But we didn’t give up, then we successfully built their vector on our E.coli rosetta strain and verified their regulatory mechanisms at different temperatures.
Mathematical models have been bothering us. The UCAS-China team provided us with practical advice on mathematical modeling, such as how to choose key parameters. In addition, we have developed a mini program related to hypertension, but we are not sure if there are some problems. The UCAS-China team assisted us in completing the mini program test and providing us with suggestions for improvement.
Because NWU-China and our projects are related to the disease, they are committed to phenylketonuria and we focus on hypertension.Since they came to shenzhen for the first time, they did not know much about the situation in shenzhen, so they hoped to get some feedback and suggestions from local residents. For this reason, we jointly organized an offline research activity in Shenzhen Bay Park. Furthermore, they also suggested that we listen to feedback from patients and businesses.