Team:ITESO Guadalajara/Parts

Team:RubisCO - 2019.igem.org

Photosynthesis is the best existing carbon fixing mechanism, though, through time and evolution, has become slow and prone to errors, losing part of its output through photorespiration, with error rates up to 40%, the call is urgent, and time and yield need to be improved [1].

Synthetic Biology has the answer to increase the aggregate efficiency of CCU technologies, by enhancing the potential of photosynthesis in a rationale of process intensification, to substitute the conventional chemical trains of operation used in the present for the conversion of CO2 into high added-value chemical intermediates.

From this grounds, RubisCO's project efforts focused on the improvement of the carbon fixing mechanisms of Synechococcus sp., and to direct the surplus of carbon flow to the synthesis of free fatty acids, as a proof of concept for the synthesis of high added-value chemical intermediates.

[1] T. J. Erb y J. Zarzycki, «A short history or RubisCO: the rise and fall of Nature ́s predominant CO2 fixing enzyme,» Current Opinion in Biotecnology, vol. 49, pp. 100-107, 2018.





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