Team:Greatbay SCIE

Description and inspiration

Have you seen poles near the ocean covered with a layer of barnacles, sticking incredibly strong to the substrate? Some marine organisms like mussels and barnacles produce and heal proteins to help them achieve differing purposes. These proteins are named the “underwater adhesives” Notably, their potentials for bioglues and coating materials are highly discussed recently. That’s why our SticKit aims to construct a toolbox of useful UNDERWATER ADHESIVES!

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Description and inspiration

Project Design

The fantastic functionalities of adhesive proteins from marine organisms have potential for BIOGLUES or coating materials.

Our project - SticKit - aimed at constructing a toolbox containing all the potential recombinant proteins (cohesive protein + adhesive protein) that has promising properties for a stronger underwater adhesion.

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Results

Eventually, microbial assembly lines of recombinant proteins were successfully created in our toolbox. mTyr-CNK, a newly discovered tyrosinase from a kind of marine archaea, enables our proteins to become stickier and stronger. We have also tried to explore further possibilities, and to fully utilize the proteins.

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Team

We are fourteen energetic high-school students who are interested in synthetic biology and devote to making some differences for the world.

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Human Practice

Our hp aims to explore the potential applications of adhesive protein in different areas. We met experts from related fields, who gave their valuable suggestions that help integrate our project design.

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Model

Our model aimed at finding the optimum expression rate of mTyr-CNK and MFP in a co-expressed system so that they can have an optimum modification rate.

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