Difference between revisions of "Team:Costa Rica/Human Practices"
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| − | {{Costa_Rica/General}}{{Costa_Rica/NavBar}}{{Costa_Rica/BootStrap}} | + | {{Costa_Rica/General}}{{Costa_Rica/NavBar}}{{Costa_Rica/BootStrap}} |
| − | <html> | + | <html> |
| − | <div class="container" style="padding-top: 50px;"> | + | <div class="container" style="padding-top: 50px;"> |
| − | + | <div class="row mb-2"> | |
| − | + | <div class="col-md-5"> | |
| − | + | <img src="https://static.igem.org/mediawiki/2019/2/23/T--Costa_Rica--team-J9.png" class="img-fluid" | |
| − | + | alt="Responsive image" style="width: 80%; margin-top:70px; margin-bottom:20px;"> | |
| − | + | <br> | |
| − | + | <p>Human practices are meant to explain why our project is important to the world. Here we present how we do | |
| − | + | an intense work to inform the people of Costa Rica about Synthetic Biology, iGEM and the new | |
| − | + | possibilities of Engineered Probiotics.</p> | |
| − | + | </div> | |
| − | + | <div class="col-md-7"> | |
| − | + | <img src="https://static.igem.org/mediawiki/2019/9/91/T--Costa_Rica--team-group.png" class="img-fluid" | |
| − | + | alt="Responsive image" style="width: 90%; float:right;"> | |
| + | </div> | ||
</div> | </div> | ||
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| − | + | <div class="row mb-2" style="margin-top:80px;margin-bottom:80px;"> | |
| − | + | <div class="col-md-6"> | |
| − | + | <center onclick="currentSlide(1)" class="medal">Public Engagement</center> | |
| − | + | </div> | |
| − | + | <div class="col-md-6"> | |
| − | + | <center onclick="currentSlide(2)" class="medal">Integrated Human Practice</center> | |
| + | |||
| + | </div> | ||
</div> | </div> | ||
| + | <style> | ||
| + | p{ | ||
| + | font-family: Montserrat; | ||
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| − | + | color: #5d5d5d; | |
| + | } | ||
| + | * { | ||
| + | box-sizing: border-box | ||
| + | } | ||
| − | + | body { | |
| − | + | font-family: Verdana, sans-serif; | |
| − | + | margin: 0 | |
| − | + | } | |
| − | + | ||
| − | + | /* Slideshow container */ | |
| − | + | .slideshow-container { | |
| − | + | position: relative; | |
| − | + | background: #FFFFFF; | |
| + | border-radius: 25px; | ||
| + | } | ||
| − | + | /* Slides */ | |
| − | + | .mySlides { | |
| − | + | display: none; | |
| − | + | margin-top: 40px; | |
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| − | + | } | |
| − | + | .medal { | |
| − | + | opacity: 0.6; | |
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| − | + | font-family: Montserrat; | |
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| − | + | line-height: normal; | |
| − | + | letter-spacing: normal; | |
| − | + | padding-bottom: 10px; | |
| − | + | color: #000000; | |
| + | } | ||
| − | + | .medal.active { | |
| − | + | font-family: Montserrat; | |
| − | + | font-size: 20px; | |
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| − | + | font-weight: 500; | |
| − | + | font-style: normal; | |
| − | + | font-stretch: normal; | |
| − | + | line-height: normal; | |
| − | + | letter-spacing: normal; | |
| − | + | color: #000000; | |
| − | + | } | |
| − | + | div.index-Menu { | |
| + | padding: 30px; | ||
| − | + | } | |
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| − | + | .medal.active:after { | |
| + | content: ""; | ||
| + | /* This is necessary for the pseudo element to work. */ | ||
| + | display: block; | ||
| + | /* This will put the pseudo element on its own line. */ | ||
| + | margin: 0 auto; | ||
| + | /* This will center the border. */ | ||
| + | width: 15%; | ||
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| + | padding-top: 10px; | ||
| + | /* This creates some space between the element and the border. */ | ||
| + | border-bottom: 3px solid #705ba0; | ||
| + | /* This creates the border. Replace black with whatever color you want. */ | ||
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| − | + | .medal:hover { | |
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| − | + | font-stretch: normal; | |
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| − | + | letter-spacing: normal; | |
| − | + | color: #000000; | |
| + | } | ||
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| + | .mySlidesB { | ||
| + | display: none; | ||
| + | margin-top: 40px; | ||
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| − | + | .mySlidesF { | |
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| − | + | /* Next & previous buttons */ | |
| − | + | .prev, | |
| − | + | .next { | |
| − | + | cursor: pointer; | |
| − | + | position: absolute; | |
| + | top: 50%; | ||
| + | width: auto; | ||
| + | margin-top: -22px; | ||
| + | padding: 16px; | ||
| + | color: white; | ||
| + | font-weight: bold; | ||
| + | font-size: 18px; | ||
| + | transition: 0.6s ease; | ||
| + | border-radius: 0 3px 3px 0; | ||
| + | user-select: none; | ||
| + | } | ||
| − | + | /* Position the "next button" to the right */ | |
| − | + | .next { | |
| − | + | right: 0; | |
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| − | + | /* On hover, add a black background color with a little bit see-through */ | |
| − | + | .prev:hover, | |
| − | + | .next:hover { | |
| − | + | background-color: rgba(0, 0, 0, 0.8); | |
| − | + | } | |
| − | + | .text { | |
| − | + | color: #f2f2f2; | |
| − | + | font-size: 15px; | |
| − | + | padding: 8px 12px; | |
| − | + | position: absolute; | |
| + | bottom: 8px; | ||
| + | width: 100%; | ||
| + | text-align: center; | ||
| + | } | ||
| + | .description-text{ | ||
| + | font-size: 15px!important; | ||
| + | font-family: Montserrat !important; | ||
| + | } | ||
| + | </style> | ||
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| + | <div class="mySlides"> | ||
| + | <div class="row"> | ||
| + | <div class="col-md-3" style=" | ||
| + | margin-left: 0em; | ||
| + | padding-right: 0px; | ||
| + | padding-left: 0.2em;"> | ||
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| + | <div class="tabs-container tabs--vertical page-navigator shadow" style=" | ||
| + | border-radius: 25px; | ||
| + | width: 300px; | ||
| + | background-color: #FFFFFF; | ||
| + | padding-bottom: 0px;margin-top: 2.4em;" id="myHeader"> | ||
| − | + | <h4 style=" | |
| − | + | padding-left: 1em; | |
| − | + | ">Index</h4> | |
| − | + | <ul class="lateral" style="padding-left: 40px;"> | |
| − | + | <li class="lateral"> | |
| − | + | <div class="tab__title " style="line-height: 1.3em;"> | |
| − | + | <a href="#inspiration" class="lateral inner-link" style=" | |
| − | + | color: #353535; | |
| − | + | opacity: 1;">Inspiration</a> | |
| − | + | </div> | |
| − | + | </li> | |
| − | + | <li class="lateral"> | |
| − | + | <div class="tab__title " style="line-height: 1.3em;"> | |
| − | + | <a href="#description" class="lateral inner-link" style=" | |
| − | + | color: #353535; | |
| − | + | opacity: 1;">Description</a> | |
| − | + | </div> | |
| − | + | </li> | |
| − | + | </ul> | |
| − | + | <ul class="tabs-content"> | |
| − | + | </ul> | |
| − | + | </div> | |
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</div> | </div> | ||
| − | |||
| − | + | <div class="col-md-9" style="padding-left: 6em;padding-right: 2em; "> | |
| − | + | <h3 class="title-text">Science Through Dance<h3> | |
| − | <p>If there is something that we can be sure of is the primitive need that human being has to understand and describe the world that surrounds us. Both science and art, are avatars of human creativity, created to facilitate the process of understanding and expressing. Nevertheless, most people use to think about them as separated fields. | + | <p>If there is something that we can be sure of is the primitive need that human being has to understand and describe the world that surrounds us. Both science and art, are avatars of human creativity, created to facilitate the process of understanding and expressing. Nevertheless, most people use to think about them as separated fields. |
| − | </p> | + | </p> |
| − | <p>That’s why, using our background in science and the experience as a dance teacher of one of our team members, we fusioned them in a special show, named Science Through Dance. | + | <p>That’s why, using our background in science and the experience as a dance teacher of one of our team members, we fusioned them in a special show, named Science Through Dance. |
| − | </p> | + | </p> |
| − | <p>The show Science Through Dance, gave us the opportunity to bring science and dance to the table, where dancers, scientists, dance parents, university teachers and many supportive people experienced, enjoyed, felt and learnt from it. It’s important to say that this space was also a way to demonstrate the capabilities of the country in these areas, which often go unnoticed or unconnected. | + | <p>The show Science Through Dance, gave us the opportunity to bring science and dance to the table, where dancers, scientists, dance parents, university teachers and many supportive people experienced, enjoyed, felt and learnt from it. It’s important to say that this space was also a way to demonstrate the capabilities of the country in these areas, which often go unnoticed or unconnected. |
| − | </p> | + | </p> |
| − | <p>To achieve the goal, we contacted scientists, dancers from all ages and one of the most famous theatres in Costa Rica. First, for science section, we counted with Rosalind Innovations, a biotech-social entrepreneurship who spoke of the magnificence of nature and the unbelievable biotech projects that emerged from it. Also, 4 chemistry students from the University of Costa Rica, elaborated an incredible show, where they made and explained amazing experiments. Additionally, our team presented the project we are taking to the iGEM competition. As for the dance section, we counted with 90 dancers from 7 to 35 years old, from beginners to nationally and internationally recognized dancers. | + | <p>To achieve the goal, we contacted scientists, dancers from all ages and one of the most famous theatres in Costa Rica. First, for science section, we counted with Rosalind Innovations, a biotech-social entrepreneurship who spoke of the magnificence of nature and the unbelievable biotech projects that emerged from it. Also, 4 chemistry students from the University of Costa Rica, elaborated an incredible show, where they made and explained amazing experiments. Additionally, our team presented the project we are taking to the iGEM competition. As for the dance section, we counted with 90 dancers from 7 to 35 years old, from beginners to nationally and internationally recognized dancers. |
| − | </p> | + | </p> |
| − | <p>Disciplines preformed were from Ballet to Jazz, Tap, Hip Hop, Contemporary, Lyric, Latin Dance, Antigravity, Break Dance and African Dance. All of them appreciated by 285 spectators. The show was covered by Novum Comunicaciones S.A., a company who took all astonishing photos you can see in the next slideshow. | + | <p>Disciplines preformed were from Ballet to Jazz, Tap, Hip Hop, Contemporary, Lyric, Latin Dance, Antigravity, Break Dance and African Dance. All of them appreciated by 285 spectators. The show was covered by Novum Comunicaciones S.A., a company who took all astonishing photos you can see in the next slideshow. |
| − | </p> | + | </p> |
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| − | + | <h2>Antibiotic resistance: A global problem</h2> | |
| − | + | <p>Since we were brainstorming about possible problems to be addressed, we quickly (not so much) | |
| − | + | stumbled upon the issue of antibiotic resistance. This phenomenon is expected to provoke up to 10 | |
| − | + | million annual deaths by 2050 (O'Neill, 2014), possibly the first death cause worldwide. This has | |
| − | + | lead the United Nations to declare antibiotic resistance as one of the greatest threats to global | |
| − | + | public health. </p> | |
| − | + | <h2>Resistant bacterial infections: Choosing our project aim</h2> | |
| − | + | <p>Antibiotic resistance is an exponential growing problem around the world and it has a very serious | |
| − | + | social impact. Looking for a solution to this problem we focused on a gastrointestinal pathogen, | |
| − | + | Clostridioides difficile. This bacteria infected patients in 21 of the 29 hospitals of Costa Rica | |
| − | + | from 2011-2014. Even one of our team members have suffered from this illness.</p> | |
| − | + | <h2>Problems: </h2> | |
| − | + | <h3>Awareness for antibiotic resistance is lacking</h3> | |
| − | + | <p>There is a worldwide ignorance on the subject of microbial resistance to antibiotics and Costa Rica | |
| − | + | is not the exception. Globally, the main cause of this problem is the misuse of antibiotics, leading | |
| − | + | to the survival of some resistant bacteria, able to spread again. Also, the bad waste management of | |
| − | + | these drugs contributes to increase resistant bacteria. This bacteria can later transfer their | |
| − | + | resistance to human microbiota (van Rijn et al., 2019). </p> | |
| − | + | <p>Research is being conducted to discover new antibiotics. However, only two new antibiotic classes | |
| − | + | (lipopeptides and oxazolidinones) have been developed and approved by international drug agencies | |
| − | + | (US Food and Drug Administration and European Medicines Agency) in the last three decades | |
| − | + | (Tacconelli et al., 2018). The field of antibiotics is not lucrative enough for pharmaceutical | |
| − | + | companies and newly discovered compounds remain similar in function to current antibiotics. As a | |
| − | + | result, only a few large companies such as GlaxoSmithKline, Novartis, Merck and Roche are still | |
| − | + | actively engaged in antibiotic research and development (Jackson, Czaplewski & Piddock, 2018).</p> | |
| − | + | <p>During our problems exploration we realized antibiotic resistance consists of the two problems | |
| − | + | mentioned above. Therefore, we decided to go out the lab to help create awareness on antibiotic | |
| − | + | resistance in our country and prove the prevalence of antibiotic resistance bacteria using the agar | |
| − | + | antibiotic resistance test.</p> | |
| − | + | <h3>Larger agar antibiotic resistance test</h3> | |
| − | + | <p>We went to the streets to have a closer encounter with people. In total we sampled 10 different | |
| − | + | places of Costa Rica: La Agonía Park in Alajuela, Central Park in Heredia, Central Park in Cartago | |
| − | + | and seven different places in San Jose (Central Park, El Mercado Central, La Sabana Metropolitan | |
| − | + | Park, France Park and the buses stations from Limón, Puntarenas and Liberia). We talked to 100 Costa | |
| − | + | Ricans, explained them a little bit of our problem and sampled their mouth with sterile swabs and | |
| − | + | following the National Health Ministry regulations. Samples were grown in petri dishes supplemented | |
| − | + | with amoxicillin (antibiotic most commonly used in Costa Rica) for 24h at 37 °C. </p> | |
| − | </html> | + | </html> |
| − | {{Costa_Rica/Interactive-Map}} | + | {{Costa_Rica/Interactive-Map}} |
| − | <html> | + | <html> |
| − | <h2>References</h2> | + | <h2>References</h2> |
| − | <p class="ref"> | + | <p class="ref"> |
| − | + | Jackson, N., Czaplewski, L., & Piddock, L. J. (2018). Discovery and development of new antibacterial drugs: learning | |
| − | + | from experience?. Journal of Antimicrobial Chemotherapy, 73(6), 1452-1459. </p> | |
| − | <p class="ref"> O’Neill, J. (2014). Antimicrobial resistance. Tackling a Crisis for the Health and Wealth of | + | <p class="ref"> O’Neill, J. (2014). Antimicrobial resistance. Tackling a Crisis for the Health and Wealth of |
| − | + | Nations. </p> | |
| − | <p class="ref"> Tacconelli, E., Carrara, E., Savoldi, A., Harbarth, S., Mendelson, M., Monnet, D. L., ... & | + | <p class="ref"> Tacconelli, E., Carrara, E., Savoldi, A., Harbarth, S., Mendelson, M., Monnet, D. L., ... & |
| − | + | Ouellette, M. (2018). Discovery, research, and development of new antibiotics: the WHO priority list of | |
| − | + | antibiotic-resistant bacteria and tuberculosis. The Lancet Infectious Diseases, 18(3), 318-327. </p> | |
| − | <p class="ref"> van Rijn, M., Haverkate, M., Achterberg, P., & Timen, A. (2019). The public uptake of | + | <p class="ref"> van Rijn, M., Haverkate, M., Achterberg, P., & Timen, A. (2019). The public uptake of |
| − | + | information about antibiotic resistance in the Netherlands. Public Understanding of Science, 28(4), | |
| − | + | 486-503. | |
| − | </p> | + | </p> |
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} | } | ||
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| − | // Add the sticky class to the navbar when you reach its scroll position. Remove "sticky" when you leave the scroll position | + | } |
| − | function myFunction() { | + | } |
| − | + | </script> | |
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| − | </script> | + | |
| − | </div> | + | |
| − | </html> | + | </html> |
| − | {{Costa_Rica/Footbar}} | + | {{Costa_Rica/Footbar}} |
Revision as of 22:36, 20 October 2019
Human practices are meant to explain why our project is important to the world. Here we present how we do
an intense work to inform the people of Costa Rica about Synthetic Biology, iGEM and the new
possibilities of Engineered Probiotics.
Public Engagement
Integrated Human Practice
Science Through Dance
If there is something that we can be sure of is the primitive need that human being has to understand and describe the world that surrounds us. Both science and art, are avatars of human creativity, created to facilitate the process of understanding and expressing. Nevertheless, most people use to think about them as separated fields.
That’s why, using our background in science and the experience as a dance teacher of one of our team members, we fusioned them in a special show, named Science Through Dance.
The show Science Through Dance, gave us the opportunity to bring science and dance to the table, where dancers, scientists, dance parents, university teachers and many supportive people experienced, enjoyed, felt and learnt from it. It’s important to say that this space was also a way to demonstrate the capabilities of the country in these areas, which often go unnoticed or unconnected.
To achieve the goal, we contacted scientists, dancers from all ages and one of the most famous theatres in Costa Rica. First, for science section, we counted with Rosalind Innovations, a biotech-social entrepreneurship who spoke of the magnificence of nature and the unbelievable biotech projects that emerged from it. Also, 4 chemistry students from the University of Costa Rica, elaborated an incredible show, where they made and explained amazing experiments. Additionally, our team presented the project we are taking to the iGEM competition. As for the dance section, we counted with 90 dancers from 7 to 35 years old, from beginners to nationally and internationally recognized dancers.
Disciplines preformed were from Ballet to Jazz, Tap, Hip Hop, Contemporary, Lyric, Latin Dance, Antigravity, Break Dance and African Dance. All of them appreciated by 285 spectators. The show was covered by Novum Comunicaciones S.A., a company who took all astonishing photos you can see in the next slideshow.
Antibiotic resistance: A global problem
Since we were brainstorming about possible problems to be addressed, we quickly (not so much)
stumbled upon the issue of antibiotic resistance. This phenomenon is expected to provoke up to 10
million annual deaths by 2050 (O'Neill, 2014), possibly the first death cause worldwide. This has
lead the United Nations to declare antibiotic resistance as one of the greatest threats to global
public health.
Resistant bacterial infections: Choosing our project aim
Antibiotic resistance is an exponential growing problem around the world and it has a very serious
social impact. Looking for a solution to this problem we focused on a gastrointestinal pathogen,
Clostridioides difficile. This bacteria infected patients in 21 of the 29 hospitals of Costa Rica
from 2011-2014. Even one of our team members have suffered from this illness.
Problems:
Awareness for antibiotic resistance is lacking
There is a worldwide ignorance on the subject of microbial resistance to antibiotics and Costa Rica
is not the exception. Globally, the main cause of this problem is the misuse of antibiotics, leading
to the survival of some resistant bacteria, able to spread again. Also, the bad waste management of
these drugs contributes to increase resistant bacteria. This bacteria can later transfer their
resistance to human microbiota (van Rijn et al., 2019).
Research is being conducted to discover new antibiotics. However, only two new antibiotic classes
(lipopeptides and oxazolidinones) have been developed and approved by international drug agencies
(US Food and Drug Administration and European Medicines Agency) in the last three decades
(Tacconelli et al., 2018). The field of antibiotics is not lucrative enough for pharmaceutical
companies and newly discovered compounds remain similar in function to current antibiotics. As a
result, only a few large companies such as GlaxoSmithKline, Novartis, Merck and Roche are still
actively engaged in antibiotic research and development (Jackson, Czaplewski & Piddock, 2018).
During our problems exploration we realized antibiotic resistance consists of the two problems
mentioned above. Therefore, we decided to go out the lab to help create awareness on antibiotic
resistance in our country and prove the prevalence of antibiotic resistance bacteria using the agar
antibiotic resistance test.
Larger agar antibiotic resistance test
We went to the streets to have a closer encounter with people. In total we sampled 10 different
places of Costa Rica: La Agonía Park in Alajuela, Central Park in Heredia, Central Park in Cartago
and seven different places in San Jose (Central Park, El Mercado Central, La Sabana Metropolitan
Park, France Park and the buses stations from Limón, Puntarenas and Liberia). We talked to 100 Costa
Ricans, explained them a little bit of our problem and sampled their mouth with sterile swabs and
following the National Health Ministry regulations. Samples were grown in petri dishes supplemented
with amoxicillin (antibiotic most commonly used in Costa Rica) for 24h at 37 °C.
References
Jackson, N., Czaplewski, L., & Piddock, L. J. (2018). Discovery and development of new antibacterial drugs: learning
from experience?. Journal of Antimicrobial Chemotherapy, 73(6), 1452-1459.
O’Neill, J. (2014). Antimicrobial resistance. Tackling a Crisis for the Health and Wealth of
Nations.
Tacconelli, E., Carrara, E., Savoldi, A., Harbarth, S., Mendelson, M., Monnet, D. L., ... &
Ouellette, M. (2018). Discovery, research, and development of new antibiotics: the WHO priority list of
antibiotic-resistant bacteria and tuberculosis. The Lancet Infectious Diseases, 18(3), 318-327.
van Rijn, M., Haverkate, M., Achterberg, P., & Timen, A. (2019). The public uptake of
information about antibiotic resistance in the Netherlands. Public Understanding of Science, 28(4),
486-503.
