Difference between revisions of "Team:Costa Rica/Human Practices"
| (57 intermediate revisions by 6 users not shown) | |||
| Line 3: | Line 3: | ||
| − | <div class="container | + | <div class="container"> |
<div class="row mb-2"> | <div class="row mb-2"> | ||
<div class="col-md-5"> | <div class="col-md-5"> | ||
<img src="https://static.igem.org/mediawiki/2019/2/23/T--Costa_Rica--team-J9.png" class="img-fluid" | <img src="https://static.igem.org/mediawiki/2019/2/23/T--Costa_Rica--team-J9.png" class="img-fluid" | ||
| − | alt="Responsive image" style="width: | + | alt="Responsive image" style="width: 70%; margin-top:70px; margin-bottom:20px;"> |
<br> | <br> | ||
| − | <p>Human practices | + | <p>Human practices' main goal is to bring our project to the general public and tell them how it is important for society. In this section, we present our efforts in informing the people of Costa Rica about Synthetic Biology, iGEM and the new |
| − | + | possibilities for Engineered Probiotics.</p> | |
| − | possibilities | + | |
</div> | </div> | ||
| Line 19: | Line 18: | ||
<div class="col-md-7"> | <div class="col-md-7"> | ||
| − | <img src="https://static.igem.org/mediawiki/2019/ | + | <img src="https://static.igem.org/mediawiki/2019/0/07/T--Costa_Rica--team-x6.png" class="img-fluid" |
alt="Responsive image" style="width: 90%; float:right;"> | alt="Responsive image" style="width: 90%; float:right;"> | ||
| Line 36: | Line 35: | ||
</div> | </div> | ||
| + | <style> | ||
| + | .readMore { | ||
| + | width: 300px; | ||
| + | height: 46px; | ||
| + | border-radius: 23px; | ||
| + | background-color: #705ba0; | ||
| + | font-family: Montserrat; | ||
| + | font-size: 16px; | ||
| + | font-weight: 500; | ||
| + | font-style: normal; | ||
| + | text-align: center; | ||
| + | color: #ffffff; | ||
| + | } | ||
| + | </style> | ||
<style> | <style> | ||
* { | * { | ||
| Line 192: | Line 205: | ||
} | } | ||
| − | |||
| − | |||
| − | |||
| − | |||
/* Position the "next button" to the right */ | /* Position the "next button" to the right */ | ||
| Line 222: | Line 231: | ||
font-size: 15px !important; | font-size: 15px !important; | ||
font-family: Montserrat !important; | font-family: Montserrat !important; | ||
| + | } | ||
| + | |||
| + | .inner-sublink { | ||
| + | font-size: 16px; | ||
} | } | ||
</style> | </style> | ||
| Line 233: | Line 246: | ||
<div class="row"> | <div class="row"> | ||
<div class="col-md-3" style=" | <div class="col-md-3" style=" | ||
| − | + | margin-left: 0em; | |
| − | + | padding-right: 0px; | |
| − | + | padding-left: 0.2em;"> | |
<div class="tabs-container tabs--vertical page-navigator shadow" style=" | <div class="tabs-container tabs--vertical page-navigator shadow" style=" | ||
| − | + | z-index:100; | |
| − | + | border-radius: 25px; | |
| − | + | width: 300px; | |
| − | + | background-color: #FFFFFF; | |
| + | padding-bottom: 0px;margin-top: 2.4em;" id="myHeader"> | ||
<h4 style=" | <h4 style=" | ||
| − | + | padding-left: 1em; | |
| − | + | ">Index</h4> | |
<ul class="lateral" style="padding-left: 40px;"> | <ul class="lateral" style="padding-left: 40px;"> | ||
<li class="lateral"> | <li class="lateral"> | ||
<div class="tab__title " style="line-height: 1.3em;"> | <div class="tab__title " style="line-height: 1.3em;"> | ||
| − | <a href="# | + | <a href="#sciencetd" class="lateral inner-link" style=" |
| − | + | color: #353535; | |
| − | + | opacity: 1;">Science Through Dance</a> | |
</div> | </div> | ||
</li> | </li> | ||
<li class="lateral"> | <li class="lateral"> | ||
<div class="tab__title " style="line-height: 1.3em;"> | <div class="tab__title " style="line-height: 1.3em;"> | ||
| − | <a href="# | + | <a href="#sdg" class="lateral inner-link" style=" |
| − | + | color: #353535; | |
| − | + | opacity: 1;">iGEMxSDG</a> | |
</div> | </div> | ||
</li> | </li> | ||
| + | <li class="lateral"> | ||
| + | <div class="tab__title " style="line-height: 1.3em;"> | ||
| + | <a href="#booklet" class="lateral inner-link" style=" | ||
| + | color: #353535; | ||
| + | opacity: 1;">Booklet</a> | ||
| + | </div> | ||
| + | |||
| + | </li> | ||
| + | <ul> | ||
| + | <li class="lateral"> | ||
| + | <div class="tab__title " style="line-height: 1.3em;"> | ||
| + | <a href="#np" class="lateral inner-sublink" style=" | ||
| + | color: #353535; | ||
| + | opacity: 1;">National Politics</a> | ||
| + | </div> | ||
| + | </li> | ||
| + | <li class="lateral"> | ||
| + | <div class="tab__title " style="line-height: 1.3em;"> | ||
| + | <a href="#hcs" class="lateral inner-sublink" style=" | ||
| + | color: #353535; | ||
| + | opacity: 1;">Healthcare System</a> | ||
| + | </div> | ||
| + | </li> | ||
| + | <li class="lateral"> | ||
| + | <div class="tab__title " style="line-height: 1.3em;"> | ||
| + | <a href="#at" class="lateral inner-sublink" style=" | ||
| + | color: #353535; | ||
| + | opacity: 1;">Academic Talks</a> | ||
| + | </div> | ||
| + | </li> | ||
| + | <li class="lateral"> | ||
| + | <div class="tab__title " style="line-height: 1.3em;"> | ||
| + | <a href="#pr" class="lateral inner-sublink" style=" | ||
| + | color: #353535; | ||
| + | opacity: 1;">Press Release</a> | ||
| + | </div> | ||
| + | </li> | ||
| + | <li class="lateral"> | ||
| + | <div class="tab__title " style="line-height: 1.3em;"> | ||
| + | <a href="#obd" class="lateral inner-sublink" style=" | ||
| + | color: #353535; | ||
| + | opacity: 1;">Our Booklet Design</a> | ||
| + | </div> | ||
| + | </li> | ||
| + | |||
| + | </ul> | ||
| + | |||
</ul> | </ul> | ||
<ul class="tabs-content"> | <ul class="tabs-content"> | ||
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<div class="col-md-9" style="padding-left: 6em;padding-right: 2em; "> | <div class="col-md-9" style="padding-left: 6em;padding-right: 2em; "> | ||
| − | <h2 class="title-text">Science Through Dance</h2> | + | <h2 class="title-text" id="sciencetd">Science Through Dance</h2> |
| − | <p>If there is something that we can be sure | + | <p>If there is something that we can be sure is the primitive need that human being has |
| − | to understand and describe the world that surrounds us. Both science and art | + | to understand and describe the world that surrounds us. Both science and art are |
avatars of human creativity, created to facilitate the process of understanding and | avatars of human creativity, created to facilitate the process of understanding and | ||
expressing. Nevertheless, most people use to think about them as separated fields. | expressing. Nevertheless, most people use to think about them as separated fields. | ||
</p> | </p> | ||
| − | <p> | + | <p>That is why, using our background in science and the experience as a dance teacher of one |
| − | of our team members, we fusioned | + | of our team members, we fusioned science and art in a special show, named Science Through Dance. |
</p> | </p> | ||
<p>The show Science Through Dance, gave us the opportunity to bring science and dance to the | <p>The show Science Through Dance, gave us the opportunity to bring science and dance to the | ||
| − | + | scenario, where dancers, scientists, dance parents, university teachers and many supportive | |
| − | people experienced, enjoyed, felt and | + | people experienced, enjoyed, felt and learned from it. It is important to say that this |
space was also a way to demonstrate the capabilities of the country in these areas, | space was also a way to demonstrate the capabilities of the country in these areas, | ||
which often go unnoticed or unconnected. | which often go unnoticed or unconnected. | ||
| Line 290: | Line 351: | ||
Innovations, a biotech-social entrepreneurship who spoke of the magnificence of nature | Innovations, a biotech-social entrepreneurship who spoke of the magnificence of nature | ||
and the unbelievable biotech projects that emerged from it. Also, 4 chemistry students | and the unbelievable biotech projects that emerged from it. Also, 4 chemistry students | ||
| − | from the University of Costa Rica, elaborated an incredible show | + | from the University of Costa Rica, elaborated an incredible show where they made and |
explained amazing experiments. Additionally, our team presented the project we are | explained amazing experiments. Additionally, our team presented the project we are | ||
taking to the iGEM competition. As for the dance section, we counted with 90 dancers | taking to the iGEM competition. As for the dance section, we counted with 90 dancers | ||
| Line 296: | Line 357: | ||
dancers. | dancers. | ||
</p> | </p> | ||
| − | <p>Disciplines preformed | + | <p>Disciplines preformed went from Ballet to Jazz, Tap, Hip Hop, Contemporary, Lyric, Latin |
Dance, Antigravity, Break Dance and African Dance. All of them appreciated by 285 | Dance, Antigravity, Break Dance and African Dance. All of them appreciated by 285 | ||
| − | spectators. The show was covered by Novum Comunicaciones S.A., a company who took all | + | spectators. The show was covered by Novum Comunicaciones S.A., a company who took all the |
astonishing photos you can see in the next slideshow. | astonishing photos you can see in the next slideshow. | ||
</p> | </p> | ||
| − | <!-- Slideshow container --> | + | <!-- Slideshow container --> |
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| − | + | ||
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| − | + | ||
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| − | + | ||
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<div class="mySlidesB "> | <div class="mySlidesB "> | ||
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| − | + | ||
| − | <img src="https://static.igem.org/mediawiki/2019/4/ | + | <img src="https://static.igem.org/mediawiki/2019/4/45/T--Costa_Rica--team-N33.png" |
class="img-fluid" style="height:500px ;filter:Flip;"> | class="img-fluid" style="height:500px ;filter:Flip;"> | ||
</div> | </div> | ||
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<!-- Next and previous buttons --> | <!-- Next and previous buttons --> | ||
| − | <a class="prev" style="color: | + | <a class="prev" style="color:white;" onclick="currentSlidePicturesB(1)">❮</a> |
| − | <a class="next" style="color: | + | <a class="next" style="color:white;" onclick="currentSlidePicturesB(-1)">❯</a> |
</div> | </div> | ||
| − | <h2>iGEMxSDGs Challenge</h2> | + | <h2 class="title-text" id="sdg">iGEMxSDGs Challenge</h2> |
| + | <div class="text-center"> | ||
| + | <img src="https://static.igem.org/mediawiki/2019/4/49/T--Costa_Rica--team-H1.png" class"img-fluid" style="width:70%;"> | ||
| + | </div> | ||
| − | |||
<p>In collaboration with the 2019 iGEM teams from Taipei American School (Taiwan) and the University | <p>In collaboration with the 2019 iGEM teams from Taipei American School (Taiwan) and the University | ||
of Tübingen (Germany), we created a challenge related with the Sustainable Development Goals | of Tübingen (Germany), we created a challenge related with the Sustainable Development Goals | ||
| − | (SDGs) proposed by the United Nations. This three continents and different time zones collab | + | (SDGs) proposed by the United Nations. This three continents and different time zones collab |
was born to promote the SDGs and show the iGEM 2019’s footprint in the advancement of a global | was born to promote the SDGs and show the iGEM 2019’s footprint in the advancement of a global | ||
sustainable development. | sustainable development. | ||
</p> | </p> | ||
| − | + | <div class="text-center" style="margin-bottom: 10px;"> | |
| + | <img src="https://static.igem.org/mediawiki/2019/thumb/2/29/T--Costa_Rica--team-N45.png/800px-T--Costa_Rica--team-N45.png.jpeg" class="center" style="width:70%;"> | ||
| + | </div> | ||
<p>iGEMxSDGs challenge’s inspiration is the current need to address the global challenges we are | <p>iGEMxSDGs challenge’s inspiration is the current need to address the global challenges we are | ||
| − | facing | + | facing confident that our challenge can impact teams |
in their fulfilment of the SDGs. | in their fulfilment of the SDGs. | ||
</p> | </p> | ||
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do the same in the next 48 hours. | do the same in the next 48 hours. | ||
</p> | </p> | ||
| − | <p>Considering the amount of tasks an iGEMer have to do | + | <p>Considering the amount of tasks an iGEMer have to do these days, we elaborated a platform in our |
| − | wiki | + | <a href="https://2019.igem.org/Team:Costa_Rica/SDG-Challenge">wiki</a> to facilitate the process. There, you just had to access from an iGEM account, |
select your team goals and easily create a collage for your social media. Also, we established a | select your team goals and easily create a collage for your social media. Also, we established a | ||
| − | hashtag for our challenge named #iGEMxSDGs, to show all team posts and motivate other teams to | + | hashtag in Instagram, Facebook and Twitter for our challenge named #iGEMxSDGs, to show all team posts and motivate other teams to |
do it. | do it. | ||
</p> | </p> | ||
<h3>Challenge Results.</h3> | <h3>Challenge Results.</h3> | ||
| − | <p>A total 74 teams participated in the hashtag challenge. The list of them is located in <a | + | <p>A total of 74 teams participated in the hashtag challenge. The list of them is located in <a |
| − | href="https://2019.igem.org/Team:Costa_Rica/Collaborations">Collaborations</a> | + | href="https://2019.igem.org/Team:Costa_Rica/Collaborations">Collaborations</a>. We shall |
| − | now discuss the most shared | + | now discuss the most shared SDGs among the participants of our challenge. |
</p> | </p> | ||
| − | + | <img src="https://static.igem.org/mediawiki/2019/3/30/T--Costa_Rica--team-N44.png" class="center" style="width:100%;"> | |
| − | + | <br> | |
| + | <br> | ||
<p><b>SDG 3. Good Health & Well Being: </b>This was the most frequent goal targeted by teams that | <p><b>SDG 3. Good Health & Well Being: </b>This was the most frequent goal targeted by teams that | ||
took part of the challenge. According to the UN, ensuring healthy lives and promoting the | took part of the challenge. According to the UN, ensuring healthy lives and promoting the | ||
well-being at all ages is essential to sustainable development. Since the 19th century, | well-being at all ages is essential to sustainable development. Since the 19th century, | ||
significant efforts have been made to eradicate all sorts of diseases, including polio, | significant efforts have been made to eradicate all sorts of diseases, including polio, | ||
| − | smallpox, and malaria in most developed countries. It is not a coincidence that most | + | smallpox, and malaria in most developed countries. It is not a coincidence that most iGEM teams |
targeted this sustainable development goal, since one of the main applications of synthetic | targeted this sustainable development goal, since one of the main applications of synthetic | ||
biology is the treatment of diseases. Whether they come from pathogens, or from pollution, most | biology is the treatment of diseases. Whether they come from pathogens, or from pollution, most | ||
| − | teams agree that the most important goal to have in mind is the | + | teams agree that the most important goal to have in mind is the health of the |
general population. This, combined with efforts in promotion and prevention, provide local | general population. This, combined with efforts in promotion and prevention, provide local | ||
communities with the necessary tools to achieve sustainable development. | communities with the necessary tools to achieve sustainable development. | ||
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<p><b>SDG 17. Partnerships for the goals: </b>Most teams agreed that partnerships are the key to | <p><b>SDG 17. Partnerships for the goals: </b>Most teams agreed that partnerships are the key to | ||
achieve major advancements in any field, specially if we are talking about development. For us, | achieve major advancements in any field, specially if we are talking about development. For us, | ||
| − | + | some of the main reasons why iGEM is unique, is because it promotes collaborations, and exchange | |
| − | of ideas between many different countries and | + | of ideas between many different countries and it promotes the interdisciplinary work. Even if a team has a project more |
| − | oriented towards local issues, | + | oriented towards local issues, it is important to document and share gathered information or |
data. You never know if someone across the world is trying to solve the same exact problem you | data. You never know if someone across the world is trying to solve the same exact problem you | ||
are facing. | are facing. | ||
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<p><b>SDG 12. Responsible Consumption and Production: </b>Climate is one of the major global | <p><b>SDG 12. Responsible Consumption and Production: </b>Climate is one of the major global | ||
concerns right now. It is necessary to adopt a responsible approach towards production and | concerns right now. It is necessary to adopt a responsible approach towards production and | ||
| − | + | discarding of every kind of goods (clothing, technology, food). It is extremely important to | |
achieve efficiency, and to minimize pollution via recycling. Being responsible with the | achieve efficiency, and to minimize pollution via recycling. Being responsible with the | ||
environment is one of the main axes of sustainable development. We need to shift our mindsets | environment is one of the main axes of sustainable development. We need to shift our mindsets | ||
| − | from “How can we produce more and | + | from “How can we produce more and cheaper?” to “How can we produce more efficiently, minimizing |
| − | our environmental | + | our environmental impact?”. A significant amount of teams agreed with this. Pollution is a small |
and large scale concern, and efforts have to be doubled in order to solve this problem. Most of | and large scale concern, and efforts have to be doubled in order to solve this problem. Most of | ||
the teams in this collaboration have projects related directly to reducing contamination in | the teams in this collaboration have projects related directly to reducing contamination in | ||
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</p> | </p> | ||
<p><b>SDG 9. Industry, Innovation and Infrastructure: </b>The fourth most shared SDG among the teams | <p><b>SDG 9. Industry, Innovation and Infrastructure: </b>The fourth most shared SDG among the teams | ||
| − | is | + | is fundamental in matters of development. Progress is absolutely necessary for |
sustainable development, and innovation is key to progress. Whether it comes from the | sustainable development, and innovation is key to progress. Whether it comes from the | ||
| − | improvement of already existing processes, or the creation of completely new technologies, | + | improvement of already existing processes, or the creation of completely new technologies, iGEM |
| − | teams agree that to make a change, | + | teams agree that to make a change, it is important to create something new and relevant. This |
| − | also closely related to the very theme of | + | also closely related to the very theme of iGEM, which is the development of synthetic biology, |
through interdisciplinary innovation. | through interdisciplinary innovation. | ||
</p> | </p> | ||
| − | <h2 class="title-text">Booklet</h2> | + | <h2 class="title-text" id="booklet">Booklet</h2> |
<p>“Synthetic biology has expanded and evolved substantially from its initial rather narrow focus to | <p>“Synthetic biology has expanded and evolved substantially from its initial rather narrow focus to | ||
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-Christina D. Smolke. | -Christina D. Smolke. | ||
</p> | </p> | ||
| − | <p>Nevertheless, this accomplishment can only be achieved | + | <p>Nevertheless, this accomplishment can only be achieved if there is enough dialogue between the |
parts involved in Synthetic Biology improvement. In Costa Rica, as in many countries, there is | parts involved in Synthetic Biology improvement. In Costa Rica, as in many countries, there is | ||
| − | still a lot to learn and discuss in this areas. And so, resources, bureaucratic processes and | + | still a lot to learn and discuss in this areas. And so, lack of resources, bureaucratic processes and |
the lack of scientific diffusion to general public are some of the problems frequently found in | the lack of scientific diffusion to general public are some of the problems frequently found in | ||
synbio investigations in our country. | synbio investigations in our country. | ||
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<p><b>• </b>Dr. Pedro Rocha, International Technology and Innovation specialist involved in | <p><b>• </b>Dr. Pedro Rocha, International Technology and Innovation specialist involved in | ||
biotechnology and biosafety issues in the Instituto Interamericano de Cooperación para la | biotechnology and biosafety issues in the Instituto Interamericano de Cooperación para la | ||
| − | Agricultura (IICA).< | + | Agricultura (IICA).<br> |
| − | + | <b>• </b>PhD. Sylvie Braibant, National Biotechnology Program Coordinator of Servicio | |
| − | Nacional de Salud Animal.< | + | Nacional de Salud Animal.<br> |
| − | + | <b>• </b>Eng. Beatriz Ortiz, Evaluator in the Registries Unit, Health Products Regulation | |
| − | Department of the Ministry of Health .< | + | Department of the Ministry of Health .<br> |
| − | + | <b>• </b>Lic. Alejandra Chaverri, Director of Regulation of Products of Health Interest of | |
| − | the Ministry of Health. < | + | the Ministry of Health. <br> |
| − | + | <b>• </b>Dr. José Ramón Salcedo, General Coordinator of the Master in Bio-Law of the | |
| − | University of Murcia < | + | University of Murcia <br> |
| − | + | <b>• </b>MSc. Alejandro Hernández, Science Director at the Ministry of Science and Technology | |
| − | for several years. < | + | for several years. <br> |
| − | + | <b>• </b>BSc. Ediner Fuentes, Ambassador of the iGEM Foundation for the CBD COP-MOP of the | |
| − | Cartagena Protocol. < | + | Cartagena Protocol. <br> |
| − | + | <b>• </b>LL.M. María Carolina Peláez Gil, Global Health Law Practitioner and International | |
Legal Consultant. </p> | Legal Consultant. </p> | ||
</div> | </div> | ||
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<div style="padding-left: 20px;"> | <div style="padding-left: 20px;"> | ||
| − | <p><b>• </b>Dr. Fernando Morales, Dean of Medicine of the University of Costa Rica.< | + | <p><b>• </b>Dr. Fernando Morales, Dean of Medicine of the University of Costa Rica.<br> |
| − | + | <b>• </b>Dr. Gustavo Leandro, Chief of Infectology of the Dr. Raúl Blanco Cervantes Hospital. | |
</p> | </p> | ||
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class="img-fluid" style="height:500px;"> | class="img-fluid" style="height:500px;"> | ||
| + | <div class="numbertext description-text">Meeting with Dr. Pedro Rocha</div> | ||
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class="img-fluid" style="height:500px;"> | class="img-fluid" style="height:500px;"> | ||
| + | <div class="numbertext description-text">Meeting with PhD. Sylvie Braibant, Eng. Beatriz Ortiz and Lic. Alejandra Chaverri. </div> | ||
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class="img-fluid" style="height:500px;"> | class="img-fluid" style="height:500px;"> | ||
| + | <div class="numbertext description-text">Meeting with the Dr. Fernando Morales, dean of Medicine of the University of Costa Rica. </div> | ||
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(que “here” sea hipervínculo al diseño del folleto, que va a estar al final). | (que “here” sea hipervínculo al diseño del folleto, que va a estar al final). | ||
</p> | </p> | ||
| − | <h3>National Politics</h3> | + | <h3 id="np">National Politics</h3> |
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| + | <div class="numbertext description-text">Reunion with the congresswoman Xiomara Rodríguez from PRN political party.</div> | ||
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class="img-fluid" style="height:500px;"> | class="img-fluid" style="height:500px;"> | ||
| + | <div class="numbertext description-text">Reunion with the congresswoman María Vita Monge from PUSC policial party.</div> | ||
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class="img-fluid" style="height:500px;"> | class="img-fluid" style="height:500px;"> | ||
| + | <div class="numbertext description-text">Reunion with some congressmen from different political parties. Left up: Erwin Masis from PUSC. Right up: Daniel Ulate from PLN and Erwin Masis. Bottom: Daniel Ulate and Wagner Jiménez from PLN.</div> | ||
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class="img-fluid" style="height:500px;"> | class="img-fluid" style="height:500px;"> | ||
| + | <div class="numbertext description-text">Reunion with different congressmen and women of different political parties. Left up: Carmen Chan from an independent political party. Right up: Zoila Volio from PIN. Left bottom: Sylvia Villegas from PIN. Right bottom: Jose María Villalta from Frente Amplio.</div> | ||
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| + | <div class="numbertext description-text">Reunion with different congressmen and women of different political parties. Left up: Dragos Donalescu from PRSC. Right up: Shirley Mejías from PUSC. Left bottom: Harllan Hoepelman from PLN. Right bottom: Walter Muñoz from PIN.</div> | ||
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| + | <div class="numbertext description-text">Reunion with congressman | ||
| + | Melvin Núñez from PRN political party.</div> | ||
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| − | + | <div class="numbertext description-text">Meeting with Luis Ramón Carranza | |
| − | <img src="https://static.igem.org/mediawiki/2019/ | + | from the PAC political party.</div> |
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| − | <h3>Health Care System</h3> | + | |
| + | <h3 id="hcs">Health Care System</h3> | ||
<p>In a meeting with Dr. Fernando Morales and Dr. Gustavo Leandro, we talked about the prospects of | <p>In a meeting with Dr. Fernando Morales and Dr. Gustavo Leandro, we talked about the prospects of | ||
synthetic biology in health. In regards of their interest on the topics discussed, they helped | synthetic biology in health. In regards of their interest on the topics discussed, they helped | ||
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public hospitals of our country. It was important for us to exchange ideas with experts of both | public hospitals of our country. It was important for us to exchange ideas with experts of both | ||
institutions because they frequently attend cases of multidrug resistant bacteria, which could | institutions because they frequently attend cases of multidrug resistant bacteria, which could | ||
| − | eventually be treated through synthetic biology solutions. | + | eventually be treated through synthetic biology solutions.</p> |
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</p> | </p> | ||
<p>During the event, we were able to share with the audience the concept of synthetic biology, how | <p>During the event, we were able to share with the audience the concept of synthetic biology, how | ||
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that have heard about it, in contrast with those who have not”. | that have heard about it, in contrast with those who have not”. | ||
</p> | </p> | ||
| − | <p> | + | <p>In hand with the above, another engagement activity we did in the Dr. Raúl Blanco Cervantes |
Hospital consisted in providing the information of the booklet to various patients and | Hospital consisted in providing the information of the booklet to various patients and | ||
companions. As this hospital is specialized in the elderly, we were able to share about | companions. As this hospital is specialized in the elderly, we were able to share about | ||
antibiotic resistance with a vulnerable public. Must of patients were really interested on the | antibiotic resistance with a vulnerable public. Must of patients were really interested on the | ||
| − | topic and they took their time to read the information provided and | + | topic and they took their time to read the information provided and asked us questions. Therefore, |
in the hospitals we were able to bring synthetic biology as an alternative closer to the Costa | in the hospitals we were able to bring synthetic biology as an alternative closer to the Costa | ||
Rican healthcare system and final beneficiaries. | Rican healthcare system and final beneficiaries. | ||
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| + | <div class="numbertext description-text">Isolation room from Raul Blanco Cervantes | ||
| + | Hospital</div> | ||
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| − | <h3>Academic Talks | + | <h3 id="at">Academic Talks |
</h3> | </h3> | ||
<p>Costa Rica is recognized as one of the leading countries in terms of education in Latin America. | <p>Costa Rica is recognized as one of the leading countries in terms of education in Latin America. | ||
| − | However, for Costa Rican educational policy and practice | + | However, for Costa Rican educational policy and practice there is a lot to improve in the field |
of science and technology. Within it, synthetic biology is undoubtedly an unexplored topic in | of science and technology. Within it, synthetic biology is undoubtedly an unexplored topic in | ||
Costa Rican education. | Costa Rican education. | ||
</p> | </p> | ||
| − | <p>Therefore, our team gave | + | <p>Therefore, our team gave a booklet and talked to high school and undergrad students who are not |
able to learn of it in order place. We introduced basic concepts of synthetic biology such as | able to learn of it in order place. We introduced basic concepts of synthetic biology such as | ||
genetic modification, recombinant proteins, domain fusions, among others. We also explained our | genetic modification, recombinant proteins, domain fusions, among others. We also explained our | ||
project diffEASY, raised awareness about the situation of Costa Rican politics regulation and | project diffEASY, raised awareness about the situation of Costa Rican politics regulation and | ||
| − | mainly, motivated them to | + | mainly, motivated them to do not lose their interest to understand their surroundings. |
</p> | </p> | ||
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<p>Our booklet aimed to engage synthetic biology with Costa Rican society too, considering the | <p>Our booklet aimed to engage synthetic biology with Costa Rican society too, considering the | ||
beliefs of general population, some of them based on disinformation. Therefore, we reached | beliefs of general population, some of them based on disinformation. Therefore, we reached | ||
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a summary with all the press publications and their reach, which had a total of 204 373 people. | a summary with all the press publications and their reach, which had a total of 204 373 people. | ||
</p> | </p> | ||
| + | <form method="get" action="https://static.igem.org/mediawiki/2019/d/d3/T--Costa_Rica--team-iGEMCRpressinfo.xls"> | ||
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| + | </form> | ||
| − | <h3>Our booklet design</h3> | + | <h3 id="obd">Our booklet design</h3> |
<p>(Hover mouse over to stop)</p> | <p>(Hover mouse over to stop)</p> | ||
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class="img-fluid" style="max-height:700px;"> </div> | class="img-fluid" style="max-height:700px;"> </div> | ||
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<p>Antibiotic resistance is an exponential growing problem around the world and it has a very serious | <p>Antibiotic resistance is an exponential growing problem around the world and it has a very serious | ||
social impact. Looking for a solution to this problem we focused on a gastrointestinal pathogen, | social impact. Looking for a solution to this problem we focused on a gastrointestinal pathogen, | ||
| − | Clostridioides difficile. This bacteria | + | <i>Clostridioides difficile</i>. This bacteria affected patients in 21 of the 29 hospitals of Costa Rica |
| − | from 2011-2014. Even one of our team members | + | from 2011-2014. Even one of our team members has suffered from this illness.</p> |
<h2>Problems: </h2> | <h2>Problems: </h2> | ||
<h3>Awareness for antibiotic resistance is lacking</h3> | <h3>Awareness for antibiotic resistance is lacking</h3> | ||
| − | <p>There is a worldwide | + | <p>There is a worldwide lack of knowledge on the subject of microbial resistance to antibiotics and Costa |
| + | Rica | ||
is not the exception. Globally, the main cause of this problem is the misuse of antibiotics, leading | is not the exception. Globally, the main cause of this problem is the misuse of antibiotics, leading | ||
to the survival of some resistant bacteria, able to spread again. Also, the bad waste management of | to the survival of some resistant bacteria, able to spread again. Also, the bad waste management of | ||
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result, only a few large companies such as GlaxoSmithKline, Novartis, Merck and Roche are still | result, only a few large companies such as GlaxoSmithKline, Novartis, Merck and Roche are still | ||
actively engaged in antibiotic research and development (Jackson, Czaplewski & Piddock, 2018).</p> | actively engaged in antibiotic research and development (Jackson, Czaplewski & Piddock, 2018).</p> | ||
| − | <p>During our problems exploration we realized antibiotic resistance consists | + | <p>During our problems exploration we realized antibiotic resistance consists on the two problems |
mentioned above. Therefore, we decided to go out the lab to help create awareness on antibiotic | mentioned above. Therefore, we decided to go out the lab to help create awareness on antibiotic | ||
resistance in our country and prove the prevalence of antibiotic resistance bacteria using the agar | resistance in our country and prove the prevalence of antibiotic resistance bacteria using the agar | ||
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| + | <p>When we attended hospital Dr. Raúl Blanco Cervantes for our Public Engagement, we talked with doctors about our project. The questions they asked and the information they provided helped us improve our solution. One of their inquietudes was whether the lysis protein will produce an immunological response in the patients. Based on that, we are considering for further research to test our enzyme in cell lines which are generally used to simulate gut responses. Also, doctors asked us if our treatment could eventually be used in complement with actual antibiotic treatments. To which we investigated more and found out that our probiotic is resistant to vancomycin, currently used to treat <i>C.difficile</i>, so it is expected that they could work together. <p> | ||
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Latest revision as of 00:23, 14 December 2019
Human practices' main goal is to bring our project to the general public and tell them how it is important for society. In this section, we present our efforts in informing the people of Costa Rica about Synthetic Biology, iGEM and the new possibilities for Engineered Probiotics.
Science Through Dance
If there is something that we can be sure is the primitive need that human being has to understand and describe the world that surrounds us. Both science and art are avatars of human creativity, created to facilitate the process of understanding and expressing. Nevertheless, most people use to think about them as separated fields.
That is why, using our background in science and the experience as a dance teacher of one of our team members, we fusioned science and art in a special show, named Science Through Dance.
The show Science Through Dance, gave us the opportunity to bring science and dance to the scenario, where dancers, scientists, dance parents, university teachers and many supportive people experienced, enjoyed, felt and learned from it. It is important to say that this space was also a way to demonstrate the capabilities of the country in these areas, which often go unnoticed or unconnected.
To achieve the goal, we contacted scientists, dancers from all ages and one of the most famous theatres in Costa Rica. First, for science section, we counted with Rosalind Innovations, a biotech-social entrepreneurship who spoke of the magnificence of nature and the unbelievable biotech projects that emerged from it. Also, 4 chemistry students from the University of Costa Rica, elaborated an incredible show where they made and explained amazing experiments. Additionally, our team presented the project we are taking to the iGEM competition. As for the dance section, we counted with 90 dancers from 7 to 35 years old, from beginners to nationally and internationally recognized dancers.
Disciplines preformed went from Ballet to Jazz, Tap, Hip Hop, Contemporary, Lyric, Latin Dance, Antigravity, Break Dance and African Dance. All of them appreciated by 285 spectators. The show was covered by Novum Comunicaciones S.A., a company who took all the astonishing photos you can see in the next slideshow.
iGEMxSDGs Challenge
In collaboration with the 2019 iGEM teams from Taipei American School (Taiwan) and the University of Tübingen (Germany), we created a challenge related with the Sustainable Development Goals (SDGs) proposed by the United Nations. This three continents and different time zones collab was born to promote the SDGs and show the iGEM 2019’s footprint in the advancement of a global sustainable development.
iGEMxSDGs challenge’s inspiration is the current need to address the global challenges we are facing confident that our challenge can impact teams in their fulfilment of the SDGs.
Every year each iGEM team targets at least one goal through their project and even more considering the human practice, collaborations and potencial outlook. Base on that, our challenge invited teams to match their targeting goals and post them on their social media. The strategy to encourage more teams consisted in a nomination chain, similar to the ice bucket challenge, where you accepted the challenge, posted your information and tagged three teams to do the same in the next 48 hours.
Considering the amount of tasks an iGEMer have to do these days, we elaborated a platform in our wiki to facilitate the process. There, you just had to access from an iGEM account, select your team goals and easily create a collage for your social media. Also, we established a hashtag in Instagram, Facebook and Twitter for our challenge named #iGEMxSDGs, to show all team posts and motivate other teams to do it.
Challenge Results.
A total of 74 teams participated in the hashtag challenge. The list of them is located in Collaborations. We shall now discuss the most shared SDGs among the participants of our challenge.
SDG 3. Good Health & Well Being: This was the most frequent goal targeted by teams that took part of the challenge. According to the UN, ensuring healthy lives and promoting the well-being at all ages is essential to sustainable development. Since the 19th century, significant efforts have been made to eradicate all sorts of diseases, including polio, smallpox, and malaria in most developed countries. It is not a coincidence that most iGEM teams targeted this sustainable development goal, since one of the main applications of synthetic biology is the treatment of diseases. Whether they come from pathogens, or from pollution, most teams agree that the most important goal to have in mind is the health of the general population. This, combined with efforts in promotion and prevention, provide local communities with the necessary tools to achieve sustainable development.
SDG 17. Partnerships for the goals: Most teams agreed that partnerships are the key to achieve major advancements in any field, specially if we are talking about development. For us, some of the main reasons why iGEM is unique, is because it promotes collaborations, and exchange of ideas between many different countries and it promotes the interdisciplinary work. Even if a team has a project more oriented towards local issues, it is important to document and share gathered information or data. You never know if someone across the world is trying to solve the same exact problem you are facing.
SDG 12. Responsible Consumption and Production: Climate is one of the major global concerns right now. It is necessary to adopt a responsible approach towards production and discarding of every kind of goods (clothing, technology, food). It is extremely important to achieve efficiency, and to minimize pollution via recycling. Being responsible with the environment is one of the main axes of sustainable development. We need to shift our mindsets from “How can we produce more and cheaper?” to “How can we produce more efficiently, minimizing our environmental impact?”. A significant amount of teams agreed with this. Pollution is a small and large scale concern, and efforts have to be doubled in order to solve this problem. Most of the teams in this collaboration have projects related directly to reducing contamination in industrial communities.
SDG 9. Industry, Innovation and Infrastructure: The fourth most shared SDG among the teams is fundamental in matters of development. Progress is absolutely necessary for sustainable development, and innovation is key to progress. Whether it comes from the improvement of already existing processes, or the creation of completely new technologies, iGEM teams agree that to make a change, it is important to create something new and relevant. This also closely related to the very theme of iGEM, which is the development of synthetic biology, through interdisciplinary innovation.
Booklet
“Synthetic biology has expanded and evolved substantially from its initial rather narrow focus to appreciate and use more fully the diversity of mechanisms found in natural biological systems” -Christina D. Smolke.
Nevertheless, this accomplishment can only be achieved if there is enough dialogue between the parts involved in Synthetic Biology improvement. In Costa Rica, as in many countries, there is still a lot to learn and discuss in this areas. And so, lack of resources, bureaucratic processes and the lack of scientific diffusion to general public are some of the problems frequently found in synbio investigations in our country.
Therefore, our team worked in the study and vinculation of synthetic biology segments needed to be strengthen in our country. These sectors include National Politics, Healthcare Systems and general public.
To gather information about the state of the art of National Politics in terms of Synthetic Biology, we interviewed experts in the topic:
• Dr. Pedro Rocha, International Technology and Innovation specialist involved in
biotechnology and biosafety issues in the Instituto Interamericano de Cooperación para la
Agricultura (IICA).
• PhD. Sylvie Braibant, National Biotechnology Program Coordinator of Servicio
Nacional de Salud Animal.
• Eng. Beatriz Ortiz, Evaluator in the Registries Unit, Health Products Regulation
Department of the Ministry of Health .
• Lic. Alejandra Chaverri, Director of Regulation of Products of Health Interest of
the Ministry of Health.
• Dr. José Ramón Salcedo, General Coordinator of the Master in Bio-Law of the
University of Murcia
• MSc. Alejandro Hernández, Science Director at the Ministry of Science and Technology
for several years.
• BSc. Ediner Fuentes, Ambassador of the iGEM Foundation for the CBD COP-MOP of the
Cartagena Protocol.
• LL.M. María Carolina Peláez Gil, Global Health Law Practitioner and International
Legal Consultant.
As for the Healthcare System, we wanted to approach to medical centers and doctors as a primary source of information and future distribution channels of synthetic biology health solutions. Therefore, we got in contact with:
• Dr. Fernando Morales, Dean of Medicine of the University of Costa Rica.
• Dr. Gustavo Leandro, Chief of Infectology of the Dr. Raúl Blanco Cervantes Hospital.
Meeting with Dr. Pedro Rocha
Meeting with PhD. Sylvie Braibant, Eng. Beatriz Ortiz and Lic. Alejandra Chaverri.
Meeting with the Dr. Fernando Morales, dean of Medicine of the University of Costa Rica.
Collected information from the interviews (explained below), we decided to elaborated a booklet looking forward to inform the three segments mentioned before. You can see the material here. (que “here” sea hipervínculo al diseño del folleto, que va a estar al final).
National Politics
Reunion with the congresswoman Xiomara Rodríguez from PRN political party.
Reunion with the congresswoman María Vita Monge from PUSC policial party.
Reunion with some congressmen from different political parties. Left up: Erwin Masis from PUSC. Right up: Daniel Ulate from PLN and Erwin Masis. Bottom: Daniel Ulate and Wagner Jiménez from PLN.
Reunion with different congressmen and women of different political parties. Left up: Carmen Chan from an independent political party. Right up: Zoila Volio from PIN. Left bottom: Sylvia Villegas from PIN. Right bottom: Jose María Villalta from Frente Amplio.
Reunion with different congressmen and women of different political parties. Left up: Dragos Donalescu from PRSC. Right up: Shirley Mejías from PUSC. Left bottom: Harllan Hoepelman from PLN. Right bottom: Walter Muñoz from PIN.
Reunion with congressman
Melvin Núñez from PRN political party.
Meeting with Luis Ramón Carranza
from the PAC political party.
Health Care System
In a meeting with Dr. Fernando Morales and Dr. Gustavo Leandro, we talked about the prospects of synthetic biology in health. In regards of their interest on the topics discussed, they helped us organize a broadcast event in the National Hospital of Geriatrics and Gerontology, Dr. Raúl Blanco Cervantes Hospital, which is also a WHO collaborative center.
The event was attended by 72 health professionals (the list of attendance is shown in the following table). Participation was not only from the Dr. Raúl Blanco Cervantes Hospital, but also from the infectology department of San Juan de Dios Hospital, both of them belong to the 29 public hospitals of our country. It was important for us to exchange ideas with experts of both institutions because they frequently attend cases of multidrug resistant bacteria, which could eventually be treated through synthetic biology solutions.
During the event, we were able to share with the audience the concept of synthetic biology, how it is applied in Costa Rica and the possible use of bioengineered microorganisms as treatment. The response of the participants about the topic was positive; however, we were interested to know if they considered that a bioengineered probiotic as a therapeutic was a possible option in our healthcare system. Among the comments we received, doctors reaffirmed to us the importance of divulging this new kind of treatments, so that the public is more recipient of it and less scared about its side effects. In words of one of the doctors: “if you publish, communicate and socialize your treatment, then it is easier for us to suggest it as a therapeutic to patients that have heard about it, in contrast with those who have not”.
In hand with the above, another engagement activity we did in the Dr. Raúl Blanco Cervantes Hospital consisted in providing the information of the booklet to various patients and companions. As this hospital is specialized in the elderly, we were able to share about antibiotic resistance with a vulnerable public. Must of patients were really interested on the topic and they took their time to read the information provided and asked us questions. Therefore, in the hospitals we were able to bring synthetic biology as an alternative closer to the Costa Rican healthcare system and final beneficiaries.
Academic Talks
Costa Rica is recognized as one of the leading countries in terms of education in Latin America. However, for Costa Rican educational policy and practice there is a lot to improve in the field of science and technology. Within it, synthetic biology is undoubtedly an unexplored topic in Costa Rican education.
Therefore, our team gave a booklet and talked to high school and undergrad students who are not able to learn of it in order place. We introduced basic concepts of synthetic biology such as genetic modification, recombinant proteins, domain fusions, among others. We also explained our project diffEASY, raised awareness about the situation of Costa Rican politics regulation and mainly, motivated them to do not lose their interest to understand their surroundings.
Press Release
Our booklet aimed to engage synthetic biology with Costa Rican society too, considering the beliefs of general population, some of them based on disinformation. Therefore, we reached different press media from our country to help us inform a larger public. It is important to emphasize that this kind of involvement with general public is key in the improvement of an informed and critical society, in order to create awareness of the possibilities with GMOs and their limitations.
Fortunately, we were featured in multiple press releases, including social media, radio and television. Notably, TV interviews were hosted in the main TV news channels of the country. Also, thanks to Kantar Media Ibope, software for press monitoring used by ITCR, here we show you a summary with all the press publications and their reach, which had a total of 204 373 people.
Our booklet design
(Hover mouse over to stop)
Antibiotic resistance: A global problem
Since we were brainstorming about possible problems to be addressed, we quickly (not so much) stumbled upon the issue of antibiotic resistance. This phenomenon is expected to provoke up to 10 million annual deaths by 2050 (O'Neill, 2014), possibly the first death cause worldwide. This has lead the United Nations to declare antibiotic resistance as one of the greatest threats to global public health.
Resistant bacterial infections: Choosing our project aim
Antibiotic resistance is an exponential growing problem around the world and it has a very serious social impact. Looking for a solution to this problem we focused on a gastrointestinal pathogen, Clostridioides difficile. This bacteria affected patients in 21 of the 29 hospitals of Costa Rica from 2011-2014. Even one of our team members has suffered from this illness.
Problems:
Awareness for antibiotic resistance is lacking
There is a worldwide lack of knowledge on the subject of microbial resistance to antibiotics and Costa Rica is not the exception. Globally, the main cause of this problem is the misuse of antibiotics, leading to the survival of some resistant bacteria, able to spread again. Also, the bad waste management of these drugs contributes to increase resistant bacteria. This bacteria can later transfer their resistance to human microbiota (van Rijn et al., 2019).
Research is being conducted to discover new antibiotics. However, only two new antibiotic classes (lipopeptides and oxazolidinones) have been developed and approved by international drug agencies (US Food and Drug Administration and European Medicines Agency) in the last three decades (Tacconelli et al., 2018). The field of antibiotics is not lucrative enough for pharmaceutical companies and newly discovered compounds remain similar in function to current antibiotics. As a result, only a few large companies such as GlaxoSmithKline, Novartis, Merck and Roche are still actively engaged in antibiotic research and development (Jackson, Czaplewski & Piddock, 2018).
During our problems exploration we realized antibiotic resistance consists on the two problems mentioned above. Therefore, we decided to go out the lab to help create awareness on antibiotic resistance in our country and prove the prevalence of antibiotic resistance bacteria using the agar antibiotic resistance test.
Larger agar antibiotic resistance test
We went to the streets to have a closer encounter with people. In total we sampled 10 different places of Costa Rica: La Agonía Park in Alajuela, Central Park in Heredia, Central Park in Cartago and seven different places in San Jose (Central Park, El Mercado Central, La Sabana Metropolitan Park, France Park and the buses stations from Limón, Puntarenas and Liberia). We talked to 100 Costa Ricans, explained them a little bit of our problem and sampled their mouth with sterile swabs and following the National Health Ministry regulations. Samples were grown in petri dishes supplemented with amoxicillin (antibiotic most commonly used in Costa Rica) for 24h at 37 °C.
Experts feedback
When we attended hospital Dr. Raúl Blanco Cervantes for our Public Engagement, we talked with doctors about our project. The questions they asked and the information they provided helped us improve our solution. One of their inquietudes was whether the lysis protein will produce an immunological response in the patients. Based on that, we are considering for further research to test our enzyme in cell lines which are generally used to simulate gut responses. Also, doctors asked us if our treatment could eventually be used in complement with actual antibiotic treatments. To which we investigated more and found out that our probiotic is resistant to vancomycin, currently used to treat C.difficile, so it is expected that they could work together.
Our meetings with doctors also helped us empathize more with our problem. It was important for us never to lose of mind that patients are the most relevant part of our project. By visiting the hospital isolation rooms for C.difficile patients and getting to know how are diagnostic and treatment methods carried out, it was easier for us to understand their needs and reaffirm the necessity of alternative methods, more effective and less disgusting, to treat this illness.
Video
References
Jackson, N., Czaplewski, L., & Piddock, L. J. (2018). Discovery and development of new antibacterial drugs: learning from experience?. Journal of Antimicrobial Chemotherapy, 73(6), 1452-1459.
O’Neill, J. (2014). Antimicrobial resistance. Tackling a Crisis for the Health and Wealth of Nations.
Tacconelli, E., Carrara, E., Savoldi, A., Harbarth, S., Mendelson, M., Monnet, D. L., ... & Ouellette, M. (2018). Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis. The Lancet Infectious Diseases, 18(3), 318-327.
van Rijn, M., Haverkate, M., Achterberg, P., & Timen, A. (2019). The public uptake of information about antibiotic resistance in the Netherlands. Public Understanding of Science, 28(4), 486-503.