Difference between revisions of "Team:Costa Rica/Human Practices"

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{{Costa_Rica/General}}{{Costa_Rica/NavBar}}{{Costa_Rica/BootStrap}}
+
    {{Costa_Rica/General}}{{Costa_Rica/NavBar}}{{Costa_Rica/BootStrap}}
<html>
+
    <html>
  
  
<div class="container">
+
    <div class="container">
  
    <div class="row mb-2">
+
        <div class="row mb-2">
        <div class="col-md-5">
+
            <div class="col-md-5">
            <img src="https://static.igem.org/mediawiki/2019/2/23/T--Costa_Rica--team-J9.png" class="img-fluid"
+
                <img src="https://static.igem.org/mediawiki/2019/2/23/T--Costa_Rica--team-J9.png" class="img-fluid"
                alt="Responsive image" style="width: 70%; margin-top:70px; margin-bottom:20px;">
+
                    alt="Responsive image" style="width: 70%; margin-top:70px; margin-bottom:20px;">
            <br>
+
                <br>
  
            <p>Human practices are meant to explain why our project is important to the world. Here we present how we do
+
                <p>Human practices are meant to explain why our project is important to the world. Here we present how we do
                an intense work to inform the people of Costa Rica about Synthetic Biology, iGEM and the new
+
                    an intense work to inform the people of Costa Rica about Synthetic Biology, iGEM and the new
                possibilities of Engineered Probiotics.</p>
+
                    possibilities of Engineered Probiotics.</p>
  
        </div>
+
            </div>
  
        <div class="col-md-7">
+
            <div class="col-md-7">
  
            <img src="https://static.igem.org/mediawiki/2019/9/91/T--Costa_Rica--team-group.png" class="img-fluid"
+
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                alt="Responsive image" style="width: 90%; float:right;">
+
                    alt="Responsive image" style="width: 90%; float:right;">
  
 +
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+
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        <div class="col-md-6">
+
            <div class="col-md-6">
            <center onclick="currentSlide(1)" class="medal">Public Engagement</center>
+
                <center onclick="currentSlide(1)" class="medal">Public Engagement</center>
  
        </div>
+
            </div>
        <div class="col-md-6">
+
            <div class="col-md-6">
            <center onclick="currentSlide(2)" class="medal">Integrated Human Practice</center>
+
                <center onclick="currentSlide(2)" class="medal">Integrated Human Practice</center>
 +
 
 +
            </div>
  
 
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        .carousel-img {
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            max-height: 500px !important;
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            padding-bottom: 40px;
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                padding-bottom: 40px;
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        .mySlidesF {
+
            /* Next & previous buttons */
             display: none;
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            .prev,
            margin-top: 40px;
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             .next {
            padding-bottom: 40px;
+
                cursor: pointer;
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+
                position: absolute;
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                top: 50%;
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                user-select: none;
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        /* Next & previous buttons */
+
            .carousel-control-prev .carousel-control-next {
        .prev,
+
                color: brown !important;
        .next {
+
            cursor: pointer;
+
            position: absolute;
+
            top: 50%;
+
            width: auto;
+
            margin-top: -22px;
+
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+
            color: white;
+
            font-weight: bold;
+
            font-size: 18px;
+
            transition: 0.6s ease;
+
            border-radius: 0 3px 3px 0;
+
            user-select: none;
+
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+
  
        .carousel-control-prev .carousel-control-next {
+
             }
             color: brown !important;
+
  
        }
+
            /* Position the "next button" to the right */
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            .next {
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                border-radius: 3px 0 0 3px;
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            }
  
        /* Position the "next button" to the right */
+
            /* On hover, add a black background color with a little bit see-through */
        .next {
+
            .prev:hover,
             right: 0;
+
             .next:hover {
            border-radius: 3px 0 0 3px;
+
                background-color: rgba(0, 0, 0, 0.8);
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+
            }
  
        /* On hover, add a black background color with a little bit see-through */
+
            .text {
        .prev:hover,
+
                color: #f2f2f2;
        .next:hover {
+
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            background-color: rgba(0, 0, 0, 0.8);
+
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+
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 +
                width: 100%;
 +
                text-align: center;
 +
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        .text {
+
            .description-text {
            color: #f2f2f2;
+
                font-size: 15px !important;
            font-size: 15px;
+
                font-family: Montserrat !important;
            padding: 8px 12px;
+
             }
             position: absolute;
+
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             bottom: 8px;
+
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+
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             text-align: center;
+
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         }
+
  
        .description-text {
 
            font-size: 15px !important;
 
            font-family: Montserrat !important;
 
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        .inner-sublink{
 
            font-size: 16px;
 
        }
 
    </style>
 
  
 +
        <div class="slideshow-container">
  
    <div class="slideshow-container">
 
  
  
 +
            <div class="mySlides">
 +
                <div class="row">
 +
                    <div class="col-md-3" style="
 +
                            margin-left: 0em;
 +
                            padding-right: 0px;
 +
                            padding-left: 0.2em;">
  
        <div class="mySlides">
 
            <div class="row">
 
                <div class="col-md-3" style="
 
                        margin-left: 0em;
 
                        padding-right: 0px;
 
                        padding-left: 0.2em;">
 
  
  
 +
                        <div class="tabs-container tabs--vertical page-navigator shadow" style="
 +
                                    border-radius: 25px;
 +
                                    width: 300px;
 +
                                    background-color: #FFFFFF;
 +
                                    padding-bottom: 0px;margin-top: 2.4em;" id="myHeader">
  
                    <div class="tabs-container tabs--vertical page-navigator shadow" style="
+
                            <h4 style="
                                 border-radius: 25px;
+
                                    padding-left: 1em;
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+
                                    ">Index</h4>
                                 background-color: #FFFFFF;
+
                            <ul class="lateral" style="padding-left: 40px;">
                                 padding-bottom: 0px;margin-top: 2.4em;" id="myHeader">
+
                                <li class="lateral">
 +
                                    <div class="tab__title " style="line-height: 1.3em;">
 +
                                        <a href="#sciencetd" class="lateral inner-link" style="
 +
                                                    color: #353535;
 +
                                                    opacity: 1;">Science Through Dance</a>
 +
                                    </div>
 +
                                </li>
 +
                                <li class="lateral">
 +
                                    <div class="tab__title " style="line-height: 1.3em;">
 +
                                        <a href="#sdg" class="lateral inner-link" style="
 +
                                                    color: #353535;
 +
                                                    opacity: 1;">iGEMxSDG</a>
 +
                                    </div>
 +
                                 </li>
 +
                                <li class="lateral">
 +
                                    <div class="tab__title " style="line-height: 1.3em;">
 +
                                        <a href="#booklet" class="lateral inner-link" style="
 +
                                                    color: #353535;
 +
                                                    opacity: 1;">Booklet</a>
 +
                                    </div>
 +
                                  
 +
                                </li>
 +
                                <ul>
 +
                                <li class="lateral">
 +
                                    <div class="tab__title " style="line-height: 1.3em;">
 +
                                        <a href="#np" class="lateral inner-sublink" style="
 +
                                                    color: #353535;
 +
                                                    opacity: 1;">National Politics</a>
 +
                                    </div>
 +
                                 </li>
 +
                                <li class="lateral">
 +
                                    <div class="tab__title " style="line-height: 1.3em;">
 +
                                        <a href="#hcs" class="lateral inner-sublink" style="
 +
                                                    color: #353535;
 +
                                                    opacity: 1;">Healthcare System</a>
 +
                                    </div>
 +
                                 </li>
 +
                                <li class="lateral">
 +
                                    <div class="tab__title " style="line-height: 1.3em;">
 +
                                        <a href="#at" class="lateral inner-sublink" style="
 +
                                                    color: #353535;
 +
                                                    opacity: 1;">Academic Talks</a>
 +
                                    </div>
 +
                                </li>
 +
                                <li class="lateral">
 +
                                    <div class="tab__title " style="line-height: 1.3em;">
 +
                                        <a href="#pr" class="lateral inner-sublink" style="
 +
                                                    color: #353535;
 +
                                                    opacity: 1;">Press Release</a>
 +
                                    </div>
 +
                                </li>
 +
                                <li class="lateral">
 +
                                    <div class="tab__title " style="line-height: 1.3em;">
 +
                                        <a href="#obd" class="lateral inner-sublink" style="
 +
                                                    color: #353535;
 +
                                                    opacity: 1;">Our Booklet Design</a>
 +
                                    </div>
 +
                                </li>
 +
 
 +
                                </ul>
  
                        <h4 style="
 
                                padding-left: 1em;
 
                                ">Index</h4>
 
                        <ul class="lateral" style="padding-left: 40px;">
 
                            <li class="lateral">
 
                                <div class="tab__title " style="line-height: 1.3em;">
 
                                    <a href="#sciencetd" class="lateral inner-link" style="
 
                                                color: #353535;
 
                                                opacity: 1;">Science Through Dance</a>
 
                                </div>
 
                            </li>
 
                            <li class="lateral">
 
                                <div class="tab__title " style="line-height: 1.3em;">
 
                                    <a href="#sdg" class="lateral inner-link" style="
 
                                                color: #353535;
 
                                                opacity: 1;">iGEMxSDG</a>
 
                                </div>
 
                            </li>
 
                            <li class="lateral">
 
                                <div class="tab__title " style="line-height: 1.3em;">
 
                                    <a href="#booklet" class="lateral inner-link" style="
 
                                                color: #353535;
 
                                                opacity: 1;">Booklet</a>
 
                                </div>
 
                           
 
                            </li>
 
                            <ul>
 
                            <li class="lateral">
 
                                <div class="tab__title " style="line-height: 1.3em;">
 
                                    <a href="#booklet" class="lateral inner-sublink" style="
 
                                                color: #353535;
 
                                                opacity: 1;">National Politics</a>
 
                                </div>
 
                            </li>
 
                            <li class="lateral">
 
                                <div class="tab__title " style="line-height: 1.3em;">
 
                                    <a href="#booklet" class="lateral inner-sublink" style="
 
                                                color: #353535;
 
                                                opacity: 1;">Healthcare System</a>
 
                                </div>
 
                            </li>
 
                            <li class="lateral">
 
                                <div class="tab__title " style="line-height: 1.3em;">
 
                                    <a href="#booklet" class="lateral inner-sublink" style="
 
                                                color: #353535;
 
                                                opacity: 1;">Academic Talks</a>
 
                                </div>
 
                            </li>
 
                            <li class="lateral">
 
                                <div class="tab__title " style="line-height: 1.3em;">
 
                                    <a href="#booklet" class="lateral inner-sublink" style="
 
                                                color: #353535;
 
                                                opacity: 1;">Press Release</a>
 
                                </div>
 
                            </li>
 
                            <li class="lateral">
 
                                <div class="tab__title " style="line-height: 1.3em;">
 
                                    <a href="#booklet" class="lateral inner-sublink" style="
 
                                                color: #353535;
 
                                                opacity: 1;">Our Booklet Design</a>
 
                                </div>
 
                            </li>
 
                            <li class="lateral">
 
                                <div class="tab__title " style="line-height: 1.3em;">
 
                                    <a href="#booklet" class="lateral inner-sublink" style="
 
                                                color: #353535;
 
                                                opacity: 1;">Booklet</a>
 
                                </div>
 
                            </li>
 
 
                             </ul>
 
                             </ul>
 
+
                            <ul class="tabs-content">
                        </ul>
+
                            </ul>
                        <ul class="tabs-content">
+
                         </div>
                         </ul>
+
 
                     </div>
 
                     </div>
                </div>
 
  
                <div class="col-md-9" style="padding-left: 6em;padding-right: 2em; ">
+
                    <div class="col-md-9" style="padding-left: 6em;padding-right: 2em; ">
                    <h2 class="title-text" id="std">Science Through Dance</h2>
+
                        <h2 class="title-text" id="std">Science Through Dance</h2>
  
                    <p>If there is something that we can be sure of is the primitive need that human being has
+
                        <p>If there is something that we can be sure of is the primitive need that human being has
                        to understand and describe the world that surrounds us. Both science and art, are
+
                            to understand and describe the world that surrounds us. Both science and art, are
                        avatars of human creativity, created to facilitate the process of understanding and
+
                            avatars of human creativity, created to facilitate the process of understanding and
                        expressing. Nevertheless, most people use to think about them as separated fields.
+
                            expressing. Nevertheless, most people use to think about them as separated fields.
                    </p>
+
                        </p>
                    <p>That’s why, using our background in science and the experience as a dance teacher of one
+
                        <p>That’s why, using our background in science and the experience as a dance teacher of one
                        of our team members, we fusioned them in a special show, named Science Through Dance.
+
                            of our team members, we fusioned them in a special show, named Science Through Dance.
                    </p>
+
                        </p>
                    <p>The show Science Through Dance, gave us the opportunity to bring science and dance to the
+
                        <p>The show Science Through Dance, gave us the opportunity to bring science and dance to the
                        table, where dancers, scientists, dance parents, university teachers and many supportive
+
                            table, where dancers, scientists, dance parents, university teachers and many supportive
                        people experienced, enjoyed, felt and learnt from it. It’s important to say that this
+
                            people experienced, enjoyed, felt and learnt from it. It’s important to say that this
                        space was also a way to demonstrate the capabilities of the country in these areas,
+
                            space was also a way to demonstrate the capabilities of the country in these areas,
                        which often go unnoticed or unconnected.
+
                            which often go unnoticed or unconnected.
                    </p>
+
                        </p>
                    <p>To achieve the goal, we contacted scientists, dancers from all ages and one of the most
+
                        <p>To achieve the goal, we contacted scientists, dancers from all ages and one of the most
                        famous theatres in Costa Rica. First, for science section, we counted with Rosalind
+
                            famous theatres in Costa Rica. First, for science section, we counted with Rosalind
                        Innovations, a biotech-social entrepreneurship who spoke of the magnificence of nature
+
                            Innovations, a biotech-social entrepreneurship who spoke of the magnificence of nature
                        and the unbelievable biotech projects that emerged from it. Also, 4 chemistry students
+
                            and the unbelievable biotech projects that emerged from it. Also, 4 chemistry students
                        from the University of Costa Rica, elaborated an incredible show, where they made and
+
                            from the University of Costa Rica, elaborated an incredible show, where they made and
                        explained amazing experiments. Additionally, our team presented the project we are
+
                            explained amazing experiments. Additionally, our team presented the project we are
                        taking to the iGEM competition. As for the dance section, we counted with 90 dancers
+
                            taking to the iGEM competition. As for the dance section, we counted with 90 dancers
                        from 7 to 35 years old, from beginners to nationally and internationally recognized
+
                            from 7 to 35 years old, from beginners to nationally and internationally recognized
                        dancers.
+
                            dancers.
                    </p>
+
                        </p>
                    <p>Disciplines preformed were from Ballet to Jazz, Tap, Hip Hop, Contemporary, Lyric, Latin
+
                        <p>Disciplines preformed were from Ballet to Jazz, Tap, Hip Hop, Contemporary, Lyric, Latin
                        Dance, Antigravity, Break Dance and African Dance. All of them appreciated by 285
+
                            Dance, Antigravity, Break Dance and African Dance. All of them appreciated by 285
                        spectators. The show was covered by Novum Comunicaciones S.A., a company who took all
+
                            spectators. The show was covered by Novum Comunicaciones S.A., a company who took all
                        astonishing photos you can see in the next slideshow.
+
                            astonishing photos you can see in the next slideshow.
                    </p>
+
                        </p>
  
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                                <img src="https://static.igem.org/mediawiki/2019/4/45/T--Costa_Rica--team-N33.png"
+
                                    <img src="https://static.igem.org/mediawiki/2019/4/45/T--Costa_Rica--team-N33.png"
                                    class="img-fluid" style="height:500px;">
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                                        class="img-fluid" style="height:500px;">
  
 +
                                </div>
 
                             </div>
 
                             </div>
                        </div>
 
  
                        <div class="mySlidesB ">
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                                <img src="https://static.igem.org/mediawiki/2019/b/bc/T--Costa_Rica--team-N34.png"
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                                    <img src="https://static.igem.org/mediawiki/2019/b/bc/T--Costa_Rica--team-N34.png"
                                    class="img-fluid" style="height:500px;">
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                                        class="img-fluid" style="height:500px;">
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                                </div>
 
                             </div>
 
                             </div>
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                                <img src="https://static.igem.org/mediawiki/2019/c/cc/T--Costa_Rica--team-N35.png"
+
                                    <img src="https://static.igem.org/mediawiki/2019/c/cc/T--Costa_Rica--team-N35.png"
                                    class="img-fluid" style="height:500px;">
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                                </div>
 
                             </div>
 
                             </div>
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                                <img src="https://static.igem.org/mediawiki/2019/9/9d/T--Costa_Rica--team-N36.png"
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                                    <img src="https://static.igem.org/mediawiki/2019/9/9d/T--Costa_Rica--team-N36.png"
                                    class="img-fluid" style="height:500px;">
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                             </div>
 
                             </div>
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                                <img src="https://static.igem.org/mediawiki/2019/6/68/T--Costa_Rica--team-N37.png"
+
                                    <img src="https://static.igem.org/mediawiki/2019/6/68/T--Costa_Rica--team-N37.png"
                                    class="img-fluid" style="height:500px;">
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                             </div>
 
                             </div>
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                                <img src="https://static.igem.org/mediawiki/2019/4/42/T--Costa_Rica--team-N38.png"
+
                                    <img src="https://static.igem.org/mediawiki/2019/4/42/T--Costa_Rica--team-N38.png"
                                    class="img-fluid" style="height:500px;">
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                                        class="img-fluid" style="height:500px;">
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                                </div>
 
                             </div>
 
                             </div>
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                                <img src="https://static.igem.org/mediawiki/2019/b/b4/T--Costa_Rica--team-N39.png"
+
                                    <img src="https://static.igem.org/mediawiki/2019/b/b4/T--Costa_Rica--team-N39.png"
                                    class="img-fluid" style="height:500px;">
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                             </div>
 
                             </div>
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                             </div>
 
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+
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 +
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                                    <img src="https://static.igem.org/mediawiki/2019/4/47/T--Costa_Rica--team-N42.png"
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                         <h2 class="title-text" id="sdg">iGEMxSDGs Challenge</h2>
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                    <h2 class="title-text" id="sdg">iGEMxSDGs Challenge</h2>
+
                        *Insertar imagen: Logo SDG
  
                    *Insertar imagen: Logo SDG
+
                        <p>In collaboration with the 2019 iGEM teams from Taipei American School (Taiwan) and the University
 +
                            of Tübingen (Germany), we created a challenge related with the Sustainable Development Goals
 +
                            (SDGs) proposed by the United Nations. This three continents and different time zones collab,
 +
                            was born to promote the SDGs and show the iGEM 2019’s footprint in the advancement of a global
 +
                            sustainable development.
 +
                        </p>
 +
                        *Foto n45*
  
                    <p>In collaboration with the 2019 iGEM teams from Taipei American School (Taiwan) and the University
+
                        <p>iGEMxSDGs challenge’s inspiration is the current need to address the global challenges we are
                         of Tübingen (Germany), we created a challenge related with the Sustainable Development Goals
+
                            facing and we will potentially face in the future, confident that our challenge can impact teams
                        (SDGs) proposed by the United Nations. This three continents and different time zones collab,
+
                            in their fulfilment of the SDGs.
                        was born to promote the SDGs and show the iGEM 2019’s footprint in the advancement of a global
+
                        </p>
                        sustainable development.
+
                        <p>Every year each iGEM team targets at least one goal through their project and even more
                    </p>
+
                            considering the human practice, collaborations and potencial outlook. Base on that, our
                    *Foto n45*
+
                            challenge invited teams to match their targeting goals and post them on their social media. The
 +
                            strategy to encourage more teams consisted in a nomination chain, similar to the ice bucket
 +
                            challenge, where you accepted the challenge, posted your information and tagged three teams to
 +
                            do the same in the next 48 hours.
 +
                         </p>
 +
                        <p>Considering the amount of tasks an iGEMer have to do this days, we elaborated a platform in our
 +
                            wiki (LINK) to facilitate the process. There, you just had to access from an iGEM account,
 +
                            select your team goals and easily create a collage for your social media. Also, we established a
 +
                            hashtag for our challenge named #iGEMxSDGs, to show all team posts and motivate other teams to
 +
                            do it.
 +
                        </p>
 +
                        <h3>Challenge Results.</h3>
 +
                        <p>A total 74 teams participated in the hashtag challenge. The list of them is located in <a
 +
                                href="https://2019.igem.org/Team:Costa_Rica/Collaborations">Collaborations</a>). We shall
 +
                            now discuss the most shared SDG’s among the participants of our challenge.
 +
                        </p>
 +
                        *insertar foto n43*
  
                    <p>iGEMxSDGs challenge’s inspiration is the current need to address the global challenges we are
+
                        <p><b>SDG 3. Good Health & Well Being: </b>This was the most frequent goal targeted by teams that
                        facing and we will potentially face in the future, confident that our challenge can impact teams
+
                            took part of the challenge. According to the UN, ensuring healthy lives and promoting the
                        in their fulfilment of the SDGs.
+
                            well-being at all ages is essential to sustainable development. Since the 19th century,
                    </p>
+
                            significant efforts have been made to eradicate all sorts of diseases, including polio,
                    <p>Every year each iGEM team targets at least one goal through their project and even more
+
                            smallpox, and malaria in most developed countries. It is not a coincidence that most iGEM teams
                        considering the human practice, collaborations and potencial outlook. Base on that, our
+
                            targeted this sustainable development goal, since one of the main applications of synthetic
                        challenge invited teams to match their targeting goals and post them on their social media. The
+
                            biology is the treatment of diseases. Whether they come from pathogens, or from pollution, most
                        strategy to encourage more teams consisted in a nomination chain, similar to the ice bucket
+
                            teams agree that the most important goal to have in mind is the well being a health of the
                        challenge, where you accepted the challenge, posted your information and tagged three teams to
+
                            general population. This, combined with efforts in promotion and prevention, provide local
                        do the same in the next 48 hours.
+
                            communities with the necessary tools to achieve sustainable development.
                    </p>
+
                        </p>
                    <p>Considering the amount of tasks an iGEMer have to do this days, we elaborated a platform in our
+
                        <p><b>SDG 17. Partnerships for the goals: </b>Most teams agreed that partnerships are the key to
                        wiki (LINK) to facilitate the process. There, you just had to access from an iGEM account,
+
                            achieve major advancements in any field, specially if we are talking about development. For us,
                        select your team goals and easily create a collage for your social media. Also, we established a
+
                            one of the main reasons why iGEM is unique, is because it promotes collaborations, and exchange
                        hashtag for our challenge named #iGEMxSDGs, to show all team posts and motivate other teams to
+
                            of ideas between many different countries and disciplines. Even if a team has a project more
                        do it.
+
                            oriented towards local issues, it’s important to document and share gathered information or
                    </p>
+
                            data. You never know if someone across the world is trying to solve the same exact problem you
                    <h3>Challenge Results.</h3>
+
                            are facing.
                    <p>A total 74 teams participated in the hashtag challenge. The list of them is located in <a
+
                        </p>
                             href="https://2019.igem.org/Team:Costa_Rica/Collaborations">Collaborations</a>). We shall
+
                        <p><b>SDG 12. Responsible Consumption and Production: </b>Climate is one of the major global
                        now discuss the most shared SDG’s among the participants of our challenge.
+
                            concerns right now. It is necessary to adopt a responsible approach towards production and
                    </p>
+
                            discard of every kind of goods (clothing, technology, food). It is extremely important to
                    *insertar foto n43*
+
                            achieve efficiency, and to minimize pollution via recycling. Being responsible with the
 +
                            environment is one of the main axes of sustainable development. We need to shift our mindsets
 +
                            from “How can we produce more and cheaper?” to “How can we produce more efficiently, minimizing
 +
                            our environmental impact?”. A significant amount of teams agreed with this. Pollution is a small
 +
                            and large scale concern, and efforts have to be doubled in order to solve this problem. Most of
 +
                            the teams in this collaboration have projects related directly to reducing contamination in
 +
                            industrial communities.
 +
                        </p>
 +
                        <p><b>SDG 9. Industry, Innovation and Infrastructure: </b>The fourth most shared SDG among the teams
 +
                            is one of the most fundamental in matter of development. Progress is absolutely necessary for
 +
                             sustainable development, and innovation is key to progress. Whether it comes from the
 +
                            improvement of already existing processes, or the creation of completely new technologies, iGEM
 +
                            teams agree that to make a change, it’s important to create something new and relevant. This
 +
                            also closely related to the very theme of iGEM, which is the development of synthetic biology,
 +
                            through interdisciplinary innovation.
 +
                        </p>
 +
                        <h2 class="title-text" id="booklet">Booklet</h2>
  
                    <p><b>SDG 3. Good Health & Well Being: </b>This was the most frequent goal targeted by teams that
+
                        <p>“Synthetic biology has expanded and evolved substantially from its initial rather narrow focus to
                         took part of the challenge. According to the UN, ensuring healthy lives and promoting the
+
                            appreciate and use more fully the diversity of mechanisms found in natural biological systems”
                        well-being at all ages is essential to sustainable development. Since the 19th century,
+
                            -Christina D. Smolke.
                        significant efforts have been made to eradicate all sorts of diseases, including polio,
+
                        </p>
                        smallpox, and malaria in most developed countries. It is not a coincidence that most iGEM teams
+
                         <p>Nevertheless, this accomplishment can only be achieved is there is enough dialogue between the
                         targeted this sustainable development goal, since one of the main applications of synthetic
+
                            parts involved in Synthetic Biology improvement. In Costa Rica, as in many countries, there is
                        biology is the treatment of diseases. Whether they come from pathogens, or from pollution, most
+
                            still a lot to learn and discuss in this areas. And so, resources, bureaucratic processes and
                         teams agree that the most important goal to have in mind is the well being a health of the
+
                            the lack of scientific diffusion to general public are some of the problems frequently found in
                        general population. This, combined with efforts in promotion and prevention, provide local
+
                            synbio investigations in our country.
                        communities with the necessary tools to achieve sustainable development.
+
                         </p>
                    </p>
+
                        <p>Therefore, our team worked in the study and vinculation of synthetic biology segments needed to
                    <p><b>SDG 17. Partnerships for the goals: </b>Most teams agreed that partnerships are the key to
+
                            be strengthen in our country. These sectors include National Politics, Healthcare Systems and
                        achieve major advancements in any field, specially if we are talking about development. For us,
+
                            general public.
                        one of the main reasons why iGEM is unique, is because it promotes collaborations, and exchange
+
                         </p>
                        of ideas between many different countries and disciplines. Even if a team has a project more
+
                        <p>To gather information about the state of the art of National Politics in terms of Synthetic
                        oriented towards local issues, it’s important to document and share gathered information or
+
                            Biology, we interviewed experts in the topic:
                        data. You never know if someone across the world is trying to solve the same exact problem you
+
                        </p>
                        are facing.
+
                        <div style="padding-left: 20px;">
                    </p>
+
                            <p><b></b>Dr. Pedro Rocha, International Technology and Innovation specialist involved in
                    <p><b>SDG 12. Responsible Consumption and Production: </b>Climate is one of the major global
+
                                biotechnology and biosafety issues in the Instituto Interamericano de Cooperación para la
                        concerns right now. It is necessary to adopt a responsible approach towards production and
+
                                Agricultura (IICA).</p>
                        discard of every kind of goods (clothing, technology, food). It is extremely important to
+
                            <p><b></b>PhD. Sylvie Braibant, National Biotechnology Program Coordinator of Servicio
                        achieve efficiency, and to minimize pollution via recycling. Being responsible with the
+
                                Nacional de Salud Animal.</p>
                        environment is one of the main axes of sustainable development. We need to shift our mindsets
+
                            <p><b>• </b>Eng. Beatriz Ortiz, Evaluator in the Registries Unit, Health Products Regulation
                        from “How can we produce more and cheaper?” to “How can we produce more efficiently, minimizing
+
                                Department of the Ministry of Health .</p>
                        our environmental impact?”. A significant amount of teams agreed with this. Pollution is a small
+
                            <p><b>• </b>Lic. Alejandra Chaverri, Director of Regulation of Products of Health Interest of
                        and large scale concern, and efforts have to be doubled in order to solve this problem. Most of
+
                                the Ministry of Health. </p>
                        the teams in this collaboration have projects related directly to reducing contamination in
+
                            <p><b>• </b>Dr. José Ramón Salcedo, General Coordinator of the Master in Bio-Law of the
                        industrial communities.
+
                                University of Murcia </p>
                    </p>
+
                            <p><b>• </b>MSc. Alejandro Hernández, Science Director at the Ministry of Science and Technology
                    <p><b>SDG 9. Industry, Innovation and Infrastructure: </b>The fourth most shared SDG among the teams
+
                                for several years. </p>
                        is one of the most fundamental in matter of development. Progress is absolutely necessary for
+
                            <p><b>• </b>BSc. Ediner Fuentes, Ambassador of the iGEM Foundation for the CBD COP-MOP of the
                        sustainable development, and innovation is key to progress. Whether it comes from the
+
                                Cartagena Protocol. </p>
                         improvement of already existing processes, or the creation of completely new technologies, iGEM
+
                            <p><b>• </b>LL.M. María Carolina Peláez Gil, Global Health Law Practitioner and International
                         teams agree that to make a change, it’s important to create something new and relevant. This
+
                                Legal Consultant. </p>
                        also closely related to the very theme of iGEM, which is the development of synthetic biology,
+
                         </div>
                        through interdisciplinary innovation.
+
                         <p>As for the Healthcare System, we wanted to approach to medical centers and doctors as a primary
                    </p>
+
                            source of information and future distribution channels of synthetic biology health solutions.
                    <h2 class="title-text" id="booklet">Booklet</h2>
+
                            Therefore, we got in contact with:</p>
  
                    <p>“Synthetic biology has expanded and evolved substantially from its initial rather narrow focus to
+
                         <div style="padding-left: 20px;">
                         appreciate and use more fully the diversity of mechanisms found in natural biological systems”
+
                            <p><b>• </b>Dr. Fernando Morales, Dean of Medicine of the University of Costa Rica.</p>
                        -Christina D. Smolke.
+
                             <p><b>• </b>Dr. Gustavo Leandro, Chief of Infectology of the Dr. Raúl Blanco Cervantes Hospital.
                    </p>
+
                             </p>
                    <p>Nevertheless, this accomplishment can only be achieved is there is enough dialogue between the
+
                         </div>
                        parts involved in Synthetic Biology improvement. In Costa Rica, as in many countries, there is
+
                        still a lot to learn and discuss in this areas. And so, resources, bureaucratic processes and
+
                        the lack of scientific diffusion to general public are some of the problems frequently found in
+
                        synbio investigations in our country.
+
                    </p>
+
                    <p>Therefore, our team worked in the study and vinculation of synthetic biology segments needed to
+
                        be strengthen in our country. These sectors include National Politics, Healthcare Systems and
+
                        general public.
+
                    </p>
+
                    <p>To gather information about the state of the art of National Politics in terms of Synthetic
+
                        Biology, we interviewed experts in the topic:
+
                    </p>
+
                    <div style="padding-left: 20px;">
+
                        <p><b>• </b>Dr. Pedro Rocha, International Technology and Innovation specialist involved in
+
                            biotechnology and biosafety issues in the Instituto Interamericano de Cooperación para la
+
                            Agricultura (IICA).</p>
+
                        <p><b>• </b>PhD. Sylvie Braibant, National Biotechnology Program Coordinator of Servicio
+
                            Nacional de Salud Animal.</p>
+
                        <p><b>• </b>Eng. Beatriz Ortiz, Evaluator in the Registries Unit, Health Products Regulation
+
                            Department of the Ministry of Health .</p>
+
                        <p><b>• </b>Lic. Alejandra Chaverri, Director of Regulation of Products of Health Interest of
+
                             the Ministry of Health. </p>
+
                        <p><b>• </b>Dr. José Ramón Salcedo, General Coordinator of the Master in Bio-Law of the
+
                            University of Murcia </p>
+
                        <p><b>• </b>MSc. Alejandro Hernández, Science Director at the Ministry of Science and Technology
+
                            for several years. </p>
+
                        <p><b>• </b>BSc. Ediner Fuentes, Ambassador of the iGEM Foundation for the CBD COP-MOP of the
+
                             Cartagena Protocol. </p>
+
                         <p><b>• </b>LL.M. María Carolina Peláez Gil, Global Health Law Practitioner and International
+
                            Legal Consultant. </p>
+
                    </div>
+
                    <p>As for the Healthcare System, we wanted to approach to medical centers and doctors as a primary
+
                        source of information and future distribution channels of synthetic biology health solutions.
+
                        Therefore, we got in contact with:</p>
+
  
                    <div style="padding-left: 20px;">
 
                        <p><b>• </b>Dr. Fernando Morales, Dean of Medicine of the University of Costa Rica.</p>
 
                        <p><b>• </b>Dr. Gustavo Leandro, Chief of Infectology of the Dr. Raúl Blanco Cervantes Hospital.
 
                        </p>
 
                    </div>
 
  
  
Line 577: Line 572:
  
  
 +
                        <div class="slideshow-container">
  
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                         <p>Collected information from the interviews (explained below), we decided to elaborated a booklet
                        <a class="prev" style="color:blueviolet;" onclick="currentSlidePicturesC(1)">&#10094;</a>
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                            looking forward to inform the three segments mentioned before. You can see the material here.
                         <a class="next" style="color:blueviolet;" onclick="currentSlidePicturesC(-1)">&#10095;</a>
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                            (que “here” sea hipervínculo al diseño del folleto, que va a estar al final).
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                         <h3 id="np">National Politics</h3>
  
                    <p>Collected information from the interviews (explained below), we decided to elaborated a booklet
 
                        looking forward to inform the three segments mentioned before. You can see the material here.
 
                        (que “here” sea hipervínculo al diseño del folleto, que va a estar al final).
 
                    </p>
 
                    <h3 id="np">National Politics</h3>
 
  
  
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                                    <div class="numbertext description-text">Reunion with the
 
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                                        congresswoman Xiomara Rodríguez</div>
                                <img src="https://static.igem.org/mediawiki/2019/6/6e/T--Costa_Rica--team-N5.png"
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                                <div class="numbertext description-text">Reunion with the
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                                    congresswoman Xiomara Rodríguez</div>
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                                    <div class="numbertext description-text">Reunion with the
                                    congresswoman María Vita Monge</div>
+
                                        congresswoman María Vita Monge</div>
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                                        class="img-fluid" style="height:500px;">
                                <div class="numbertext description-text">Reunion with some
+
                                    <div class="numbertext description-text">Reunion with some
                                    congressmen of the PUSC political party</div>
+
                                        congressmen of the PUSC political party</div>
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                                <img src="https://static.igem.org/mediawiki/2019/1/19/T--Costa_Rica--team-N30.png"
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                                    <img src="https://static.igem.org/mediawiki/2019/1/19/T--Costa_Rica--team-N30.png"
                                    class="img-fluid" style="height:500px;">
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                                        class="img-fluid" style="height:500px;">
                                <div class="numbertext description-text">Reunion with different
+
                                    <div class="numbertext description-text">Reunion with different
                                    congressmen and women of different political parties</div>
+
                                        congressmen and women of different political parties</div>
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                                    <img src="https://static.igem.org/mediawiki/2019/1/1b/T--Costa_Rica--team-N31.png"
                                    class="img-fluid" style="height:500px;">
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                                        class="img-fluid" style="height:500px;">
                                <div class="numbertext description-text">Reunion with different
+
                                    <div class="numbertext description-text">Reunion with different
                                    congressmen and women of different political parties</div>
+
                                        congressmen and women of different political parties</div>
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                                <div class="numbertext description-text">Reunion with congressman
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                                    <div class="numbertext description-text">Reunion with congressman
                                    Melvin Núñez from the PRN political party.</div>
+
                                        Melvin Núñez from the PRN political party.</div>
 +
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                                <div class="numbertext description-text">Reunion with Ramón Carranza
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                                    <div class="numbertext description-text">Reunion with Ramón Carranza
                                    from the PAC political party.</div>
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                                        from the PAC political party.</div>
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                <h3 id="hcs">Health Care System</h3>
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                    <h3 id="hcs">Health Care System</h3>
                <p>In a meeting with Dr. Fernando Morales and Dr. Gustavo Leandro, we talked about the prospects of
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                    <p>In a meeting with Dr. Fernando Morales and Dr. Gustavo Leandro, we talked about the prospects of
                    synthetic biology in health. In regards of their interest on the topics discussed, they helped
+
                        synthetic biology in health. In regards of their interest on the topics discussed, they helped
                    us organize a broadcast event in the National Hospital of Geriatrics and Gerontology, Dr. Raúl
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                        us organize a broadcast event in the National Hospital of Geriatrics and Gerontology, Dr. Raúl
                    Blanco Cervantes Hospital, which is also a WHO collaborative center.
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                        Blanco Cervantes Hospital, which is also a WHO collaborative center.
                </p>
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                    </p>
                <p>The event was attended by 72 health professionals (the list of attendance is shown in the
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                    <p>The event was attended by 72 health professionals (the list of attendance is shown in the
                    following table). Participation was not only from the Dr. Raúl Blanco Cervantes Hospital, but
+
                        following table). Participation was not only from the Dr. Raúl Blanco Cervantes Hospital, but
                    also from the infectology department of San Juan de Dios Hospital, both of them belong to the 29
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                        also from the infectology department of San Juan de Dios Hospital, both of them belong to the 29
                    public hospitals of our country. It was important for us to exchange ideas with experts of both
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                        public hospitals of our country. It was important for us to exchange ideas with experts of both
                    institutions because they frequently attend cases of multidrug resistant bacteria, which could
+
                        institutions because they frequently attend cases of multidrug resistant bacteria, which could
                    eventually be treated through synthetic biology solutions.
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                        eventually be treated through synthetic biology solutions.
                </p>
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                    </p>
                <p>During the event, we were able to share with the audience the concept of synthetic biology, how
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                    <p>During the event, we were able to share with the audience the concept of synthetic biology, how
                    it is applied in Costa Rica and the possible use of bioengineered microorganisms as treatment.
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                        it is applied in Costa Rica and the possible use of bioengineered microorganisms as treatment.
                    The response of the participants about the topic was positive; however, we were interested to
+
                        The response of the participants about the topic was positive; however, we were interested to
                    know if they considered that a bioengineered probiotic as a therapeutic was a possible option in
+
                        know if they considered that a bioengineered probiotic as a therapeutic was a possible option in
                    our healthcare system. Among the comments we received, doctors reaffirmed to us the importance
+
                        our healthcare system. Among the comments we received, doctors reaffirmed to us the importance
                    of divulging this new kind of treatments, so that the public is more recipient of it and less
+
                        of divulging this new kind of treatments, so that the public is more recipient of it and less
                    scared about its side effects. In words of one of the doctors: “if you publish, communicate and
+
                        scared about its side effects. In words of one of the doctors: “if you publish, communicate and
                    socialize your treatment, then it is easier for us to suggest it as a therapeutic to patients
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                        socialize your treatment, then it is easier for us to suggest it as a therapeutic to patients
                    that have heard about it, in contrast with those who have not”.
+
                        that have heard about it, in contrast with those who have not”.
                </p>
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                    </p>
                <p>Hand in hand with the above, another engagement activity we did in the Dr. Raúl Blanco Cervantes
+
                    <p>Hand in hand with the above, another engagement activity we did in the Dr. Raúl Blanco Cervantes
                    Hospital consisted in providing the information of the booklet to various patients and
+
                        Hospital consisted in providing the information of the booklet to various patients and
                    companions. As this hospital is specialized in the elderly, we were able to share about
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                        companions. As this hospital is specialized in the elderly, we were able to share about
                    antibiotic resistance with a vulnerable public. Must of patients were really interested on the
+
                        antibiotic resistance with a vulnerable public. Must of patients were really interested on the
                    topic and they took their time to read the information provided and ask us questions. Therefore,
+
                        topic and they took their time to read the information provided and ask us questions. Therefore,
                    in the hospitals we were able to bring synthetic biology as an alternative closer to the Costa
+
                        in the hospitals we were able to bring synthetic biology as an alternative closer to the Costa
                    Rican healthcare system and final beneficiaries.
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                        Rican healthcare system and final beneficiaries.
                </p>
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                            <div class="numbertext description-text">Isolation room from Raul Blanco Cervantes Hospital</div>
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                                <div class="numbertext description-text">Isolation room from Raul Blanco Cervantes Hospital</div>
  
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                <h3 id="at">Academic Talks
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                    <h3 id="at">Academic Talks
                </h3>
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                    </h3>
                <p>Costa Rica is recognized as one of the leading countries in terms of education in Latin America.
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                    <p>Costa Rica is recognized as one of the leading countries in terms of education in Latin America.
                    However, for Costa Rican educational policy and practice there’s a lot to improve in the field
+
                        However, for Costa Rican educational policy and practice there’s a lot to improve in the field
                    of science and technology. Within it, synthetic biology is undoubtedly an unexplored topic in
+
                        of science and technology. Within it, synthetic biology is undoubtedly an unexplored topic in
                    Costa Rican education.
+
                        Costa Rican education.
                </p>
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                    </p>
                <p>Therefore, our team gave the booklet and talked to high school and undergrad students who aren’t
+
                    <p>Therefore, our team gave the booklet and talked to high school and undergrad students who aren’t
                    able to learn of it in order place. We introduced basic concepts of synthetic biology such as
+
                        able to learn of it in order place. We introduced basic concepts of synthetic biology such as
                    genetic modification, recombinant proteins, domain fusions, among others. We also explained our
+
                        genetic modification, recombinant proteins, domain fusions, among others. We also explained our
                    project diffEASY, raised awareness about the situation of Costa Rican politics regulation and
+
                        project diffEASY, raised awareness about the situation of Costa Rican politics regulation and
                    mainly, motivated them to don’t lose their interest to understand their surroundings.
+
                        mainly, motivated them to don’t lose their interest to understand their surroundings.
                </p>
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                    </p>
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                    <div class="numbertext description-text">Talk at the "Colegio Madre del Divino Pastor"</div>
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                        <div class="numbertext description-text">Talk at the "Colegio Madre del Divino Pastor"</div>
                </div>
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                    </div>
  
  
  
                <h3 id="pr">Press Release</h3>
+
                    <h3 id="pr">Press Release</h3>
                <p>Our booklet aimed to engage synthetic biology with Costa Rican society too, considering the
+
                    <p>Our booklet aimed to engage synthetic biology with Costa Rican society too, considering the
                    beliefs of general population, some of them based on disinformation. Therefore, we reached
+
                        beliefs of general population, some of them based on disinformation. Therefore, we reached
                    different press media from our country to help us inform a larger public. It is important to
+
                        different press media from our country to help us inform a larger public. It is important to
                    emphasize that this kind of involvement with general public is key in the improvement of an
+
                        emphasize that this kind of involvement with general public is key in the improvement of an
                    informed and critical society, in order to create awareness of the possibilities with GMOs and
+
                        informed and critical society, in order to create awareness of the possibilities with GMOs and
                    their limitations.
+
                        their limitations.
                </p>
+
                    </p>
                <p>Fortunately, we were featured in multiple press releases, including social media, radio and
+
                    <p>Fortunately, we were featured in multiple press releases, including social media, radio and
                    television. Notably, TV interviews were hosted in the main TV news channels of the country.
+
                        television. Notably, TV interviews were hosted in the main TV news channels of the country.
                    Also, thanks to Kantar Media Ibope, software for press monitoring used by ITCR, here we show you
+
                        Also, thanks to Kantar Media Ibope, software for press monitoring used by ITCR, here we show you
                    a summary with all the press publications and their reach, which had a total of 204 373 people.
+
                        a summary with all the press publications and their reach, which had a total of 204 373 people.
                </p>
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                    </p>
  
  
  
                <h3 id="obd">Our booklet design</h3>
+
                    <h3 id="obd">Our booklet design</h3>
                <p>(Hover mouse over to stop)</p>
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                    <p>(Hover mouse over to stop)</p>
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        <h2>Antibiotic resistance: A global problem</h2>
+
            <h2>Antibiotic resistance: A global problem</h2>
  
        <p>Since we were brainstorming about possible problems to be addressed, we quickly (not so much)
+
            <p>Since we were brainstorming about possible problems to be addressed, we quickly (not so much)
            stumbled upon the issue of antibiotic resistance. This phenomenon is expected to provoke up to 10
+
                stumbled upon the issue of antibiotic resistance. This phenomenon is expected to provoke up to 10
            million annual deaths by 2050 (O'Neill, 2014), possibly the first death cause worldwide. This has
+
                million annual deaths by 2050 (O'Neill, 2014), possibly the first death cause worldwide. This has
            lead the United Nations to declare antibiotic resistance as one of the greatest threats to global
+
                lead the United Nations to declare antibiotic resistance as one of the greatest threats to global
            public health. </p>
+
                public health. </p>
  
  
        <h2>Resistant bacterial infections: Choosing our project aim</h2>
+
            <h2>Resistant bacterial infections: Choosing our project aim</h2>
  
        <p>Antibiotic resistance is an exponential growing problem around the world and it has a very serious
+
            <p>Antibiotic resistance is an exponential growing problem around the world and it has a very serious
            social impact. Looking for a solution to this problem we focused on a gastrointestinal pathogen,
+
                social impact. Looking for a solution to this problem we focused on a gastrointestinal pathogen,
            <i>Clostridioides difficile</i>. This bacteria infected patients in 21 of the 29 hospitals of Costa Rica
+
                <i>Clostridioides difficile</i>. This bacteria infected patients in 21 of the 29 hospitals of Costa Rica
            from 2011-2014. Even one of our team members has suffered from this illness.</p>
+
                from 2011-2014. Even one of our team members has suffered from this illness.</p>
  
        <h2>Problems: </h2>
+
            <h2>Problems: </h2>
        <h3>Awareness for antibiotic resistance is lacking</h3>
+
            <h3>Awareness for antibiotic resistance is lacking</h3>
  
        <p>There is a worldwide lack of knowledge on the subject of microbial resistance to antibiotics and Costa Rica
+
            <p>There is a worldwide lack of knowledge on the subject of microbial resistance to antibiotics and Costa Rica
            is not the exception. Globally, the main cause of this problem is the misuse of antibiotics, leading
+
                is not the exception. Globally, the main cause of this problem is the misuse of antibiotics, leading
            to the survival of some resistant bacteria, able to spread again. Also, the bad waste management of
+
                to the survival of some resistant bacteria, able to spread again. Also, the bad waste management of
            these drugs contributes to increase resistant bacteria. This bacteria can later transfer their
+
                these drugs contributes to increase resistant bacteria. This bacteria can later transfer their
            resistance to human microbiota (van Rijn et al., 2019). </p>
+
                resistance to human microbiota (van Rijn et al., 2019). </p>
        <p>Research is being conducted to discover new antibiotics. However, only two new antibiotic classes
+
            <p>Research is being conducted to discover new antibiotics. However, only two new antibiotic classes
            (lipopeptides and oxazolidinones) have been developed and approved by international drug agencies
+
                (lipopeptides and oxazolidinones) have been developed and approved by international drug agencies
            (US Food and Drug Administration and European Medicines Agency) in the last three decades
+
                (US Food and Drug Administration and European Medicines Agency) in the last three decades
            (Tacconelli et al., 2018). The field of antibiotics is not lucrative enough for pharmaceutical
+
                (Tacconelli et al., 2018). The field of antibiotics is not lucrative enough for pharmaceutical
            companies and newly discovered compounds remain similar in function to current antibiotics. As a
+
                companies and newly discovered compounds remain similar in function to current antibiotics. As a
            result, only a few large companies such as GlaxoSmithKline, Novartis, Merck and Roche are still
+
                result, only a few large companies such as GlaxoSmithKline, Novartis, Merck and Roche are still
            actively engaged in antibiotic research and development (Jackson, Czaplewski & Piddock, 2018).</p>
+
                actively engaged in antibiotic research and development (Jackson, Czaplewski & Piddock, 2018).</p>
        <p>During our problems exploration we realized antibiotic resistance consists on the two problems
+
            <p>During our problems exploration we realized antibiotic resistance consists on the two problems
            mentioned above. Therefore, we decided to go out the lab to help create awareness on antibiotic
+
                mentioned above. Therefore, we decided to go out the lab to help create awareness on antibiotic
            resistance in our country and prove the prevalence of antibiotic resistance bacteria using the agar
+
                resistance in our country and prove the prevalence of antibiotic resistance bacteria using the agar
            antibiotic resistance test.</p>
+
                antibiotic resistance test.</p>
  
        <h3>Larger agar antibiotic resistance test</h3>
+
            <h3>Larger agar antibiotic resistance test</h3>
  
  
        <p>We went to the streets to have a closer encounter with people. In total we sampled 10 different
+
            <p>We went to the streets to have a closer encounter with people. In total we sampled 10 different
            places of Costa Rica: La Agonía Park in Alajuela, Central Park in Heredia, Central Park in Cartago
+
                places of Costa Rica: La Agonía Park in Alajuela, Central Park in Heredia, Central Park in Cartago
            and seven different places in San Jose (Central Park, El Mercado Central, La Sabana Metropolitan
+
                and seven different places in San Jose (Central Park, El Mercado Central, La Sabana Metropolitan
            Park, France Park and the buses stations from Limón, Puntarenas and Liberia). We talked to 100 Costa
+
                Park, France Park and the buses stations from Limón, Puntarenas and Liberia). We talked to 100 Costa
            Ricans, explained them a little bit of our problem and sampled their mouth with sterile swabs and
+
                Ricans, explained them a little bit of our problem and sampled their mouth with sterile swabs and
            following the National Health Ministry regulations. Samples were grown in petri dishes supplemented
+
                following the National Health Ministry regulations. Samples were grown in petri dishes supplemented
            with amoxicillin (antibiotic most commonly used in Costa Rica) for 24h at 37 °C. </p>
+
                with amoxicillin (antibiotic most commonly used in Costa Rica) for 24h at 37 °C. </p>
  
</html>
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<h2>References</h2>
+
    <h2>References</h2>
<p class="ref">
+
    <p class="ref">
    Jackson, N., Czaplewski, L., & Piddock, L. J. (2018). Discovery and development of new antibacterial drugs: learning
+
        Jackson, N., Czaplewski, L., & Piddock, L. J. (2018). Discovery and development of new antibacterial drugs: learning
    from experience?. Journal of Antimicrobial Chemotherapy, 73(6), 1452-1459. </p>
+
        from experience?. Journal of Antimicrobial Chemotherapy, 73(6), 1452-1459. </p>
  
<p class="ref"> O’Neill, J. (2014). Antimicrobial resistance. Tackling a Crisis for the Health and Wealth of
+
    <p class="ref"> O’Neill, J. (2014). Antimicrobial resistance. Tackling a Crisis for the Health and Wealth of
    Nations. </p>
+
        Nations. </p>
  
<p class="ref"> Tacconelli, E., Carrara, E., Savoldi, A., Harbarth, S., Mendelson, M., Monnet, D. L., ... &
+
    <p class="ref"> Tacconelli, E., Carrara, E., Savoldi, A., Harbarth, S., Mendelson, M., Monnet, D. L., ... &
    Ouellette, M. (2018). Discovery, research, and development of new antibiotics: the WHO priority list of
+
        Ouellette, M. (2018). Discovery, research, and development of new antibiotics: the WHO priority list of
    antibiotic-resistant bacteria and tuberculosis. The Lancet Infectious Diseases, 18(3), 318-327. </p>
+
        antibiotic-resistant bacteria and tuberculosis. The Lancet Infectious Diseases, 18(3), 318-327. </p>
  
<p class="ref"> van Rijn, M., Haverkate, M., Achterberg, P., & Timen, A. (2019). The public uptake of
+
    <p class="ref"> van Rijn, M., Haverkate, M., Achterberg, P., & Timen, A. (2019). The public uptake of
    information about antibiotic resistance in the Netherlands. Public Understanding of Science, 28(4),
+
        information about antibiotic resistance in the Netherlands. Public Understanding of Science, 28(4),
    486-503.
+
        486-503.
</p>
+
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Revision as of 01:53, 21 October 2019

   





























    
    










   


    
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Human practices are meant to explain why our project is important to the world. Here we present how we do an intense work to inform the people of Costa Rica about Synthetic Biology, iGEM and the new possibilities of Engineered Probiotics.

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Public Engagement
Integrated Human Practice

Science Through Dance

If there is something that we can be sure of is the primitive need that human being has to understand and describe the world that surrounds us. Both science and art, are avatars of human creativity, created to facilitate the process of understanding and expressing. Nevertheless, most people use to think about them as separated fields.

That’s why, using our background in science and the experience as a dance teacher of one of our team members, we fusioned them in a special show, named Science Through Dance.

The show Science Through Dance, gave us the opportunity to bring science and dance to the table, where dancers, scientists, dance parents, university teachers and many supportive people experienced, enjoyed, felt and learnt from it. It’s important to say that this space was also a way to demonstrate the capabilities of the country in these areas, which often go unnoticed or unconnected.

To achieve the goal, we contacted scientists, dancers from all ages and one of the most famous theatres in Costa Rica. First, for science section, we counted with Rosalind Innovations, a biotech-social entrepreneurship who spoke of the magnificence of nature and the unbelievable biotech projects that emerged from it. Also, 4 chemistry students from the University of Costa Rica, elaborated an incredible show, where they made and explained amazing experiments. Additionally, our team presented the project we are taking to the iGEM competition. As for the dance section, we counted with 90 dancers from 7 to 35 years old, from beginners to nationally and internationally recognized dancers.

Disciplines preformed were from Ballet to Jazz, Tap, Hip Hop, Contemporary, Lyric, Latin Dance, Antigravity, Break Dance and African Dance. All of them appreciated by 285 spectators. The show was covered by Novum Comunicaciones S.A., a company who took all astonishing photos you can see in the next slideshow.

iGEMxSDGs Challenge

*Insertar imagen: Logo SDG

In collaboration with the 2019 iGEM teams from Taipei American School (Taiwan) and the University of Tübingen (Germany), we created a challenge related with the Sustainable Development Goals (SDGs) proposed by the United Nations. This three continents and different time zones collab, was born to promote the SDGs and show the iGEM 2019’s footprint in the advancement of a global sustainable development.

*Foto n45*

iGEMxSDGs challenge’s inspiration is the current need to address the global challenges we are facing and we will potentially face in the future, confident that our challenge can impact teams in their fulfilment of the SDGs.

Every year each iGEM team targets at least one goal through their project and even more considering the human practice, collaborations and potencial outlook. Base on that, our challenge invited teams to match their targeting goals and post them on their social media. The strategy to encourage more teams consisted in a nomination chain, similar to the ice bucket challenge, where you accepted the challenge, posted your information and tagged three teams to do the same in the next 48 hours.

Considering the amount of tasks an iGEMer have to do this days, we elaborated a platform in our wiki (LINK) to facilitate the process. There, you just had to access from an iGEM account, select your team goals and easily create a collage for your social media. Also, we established a hashtag for our challenge named #iGEMxSDGs, to show all team posts and motivate other teams to do it.

Challenge Results.

A total 74 teams participated in the hashtag challenge. The list of them is located in Collaborations). We shall now discuss the most shared SDG’s among the participants of our challenge.

*insertar foto n43*

SDG 3. Good Health & Well Being: This was the most frequent goal targeted by teams that took part of the challenge. According to the UN, ensuring healthy lives and promoting the well-being at all ages is essential to sustainable development. Since the 19th century, significant efforts have been made to eradicate all sorts of diseases, including polio, smallpox, and malaria in most developed countries. It is not a coincidence that most iGEM teams targeted this sustainable development goal, since one of the main applications of synthetic biology is the treatment of diseases. Whether they come from pathogens, or from pollution, most teams agree that the most important goal to have in mind is the well being a health of the general population. This, combined with efforts in promotion and prevention, provide local communities with the necessary tools to achieve sustainable development.

SDG 17. Partnerships for the goals: Most teams agreed that partnerships are the key to achieve major advancements in any field, specially if we are talking about development. For us, one of the main reasons why iGEM is unique, is because it promotes collaborations, and exchange of ideas between many different countries and disciplines. Even if a team has a project more oriented towards local issues, it’s important to document and share gathered information or data. You never know if someone across the world is trying to solve the same exact problem you are facing.

SDG 12. Responsible Consumption and Production: Climate is one of the major global concerns right now. It is necessary to adopt a responsible approach towards production and discard of every kind of goods (clothing, technology, food). It is extremely important to achieve efficiency, and to minimize pollution via recycling. Being responsible with the environment is one of the main axes of sustainable development. We need to shift our mindsets from “How can we produce more and cheaper?” to “How can we produce more efficiently, minimizing our environmental impact?”. A significant amount of teams agreed with this. Pollution is a small and large scale concern, and efforts have to be doubled in order to solve this problem. Most of the teams in this collaboration have projects related directly to reducing contamination in industrial communities.

SDG 9. Industry, Innovation and Infrastructure: The fourth most shared SDG among the teams is one of the most fundamental in matter of development. Progress is absolutely necessary for sustainable development, and innovation is key to progress. Whether it comes from the improvement of already existing processes, or the creation of completely new technologies, iGEM teams agree that to make a change, it’s important to create something new and relevant. This also closely related to the very theme of iGEM, which is the development of synthetic biology, through interdisciplinary innovation.

Booklet

“Synthetic biology has expanded and evolved substantially from its initial rather narrow focus to appreciate and use more fully the diversity of mechanisms found in natural biological systems” -Christina D. Smolke.

Nevertheless, this accomplishment can only be achieved is there is enough dialogue between the parts involved in Synthetic Biology improvement. In Costa Rica, as in many countries, there is still a lot to learn and discuss in this areas. And so, resources, bureaucratic processes and the lack of scientific diffusion to general public are some of the problems frequently found in synbio investigations in our country.

Therefore, our team worked in the study and vinculation of synthetic biology segments needed to be strengthen in our country. These sectors include National Politics, Healthcare Systems and general public.

To gather information about the state of the art of National Politics in terms of Synthetic Biology, we interviewed experts in the topic:

Dr. Pedro Rocha, International Technology and Innovation specialist involved in biotechnology and biosafety issues in the Instituto Interamericano de Cooperación para la Agricultura (IICA).

PhD. Sylvie Braibant, National Biotechnology Program Coordinator of Servicio Nacional de Salud Animal.

Eng. Beatriz Ortiz, Evaluator in the Registries Unit, Health Products Regulation Department of the Ministry of Health .

Lic. Alejandra Chaverri, Director of Regulation of Products of Health Interest of the Ministry of Health.

Dr. José Ramón Salcedo, General Coordinator of the Master in Bio-Law of the University of Murcia

MSc. Alejandro Hernández, Science Director at the Ministry of Science and Technology for several years.

BSc. Ediner Fuentes, Ambassador of the iGEM Foundation for the CBD COP-MOP of the Cartagena Protocol.

LL.M. María Carolina Peláez Gil, Global Health Law Practitioner and International Legal Consultant.

As for the Healthcare System, we wanted to approach to medical centers and doctors as a primary source of information and future distribution channels of synthetic biology health solutions. Therefore, we got in contact with:

Dr. Fernando Morales, Dean of Medicine of the University of Costa Rica.

Dr. Gustavo Leandro, Chief of Infectology of the Dr. Raúl Blanco Cervantes Hospital.

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Collected information from the interviews (explained below), we decided to elaborated a booklet looking forward to inform the three segments mentioned before. You can see the material here. (que “here” sea hipervínculo al diseño del folleto, que va a estar al final).

National Politics

Reunion with the congresswoman Xiomara Rodríguez
Reunion with the congresswoman María Vita Monge
Reunion with some congressmen of the PUSC political party
Reunion with different congressmen and women of different political parties
Reunion with different congressmen and women of different political parties
Reunion with congressman Melvin Núñez from the PRN political party.
Reunion with Ramón Carranza from the PAC political party.

Health Care System

In a meeting with Dr. Fernando Morales and Dr. Gustavo Leandro, we talked about the prospects of synthetic biology in health. In regards of their interest on the topics discussed, they helped us organize a broadcast event in the National Hospital of Geriatrics and Gerontology, Dr. Raúl Blanco Cervantes Hospital, which is also a WHO collaborative center.

The event was attended by 72 health professionals (the list of attendance is shown in the following table). Participation was not only from the Dr. Raúl Blanco Cervantes Hospital, but also from the infectology department of San Juan de Dios Hospital, both of them belong to the 29 public hospitals of our country. It was important for us to exchange ideas with experts of both institutions because they frequently attend cases of multidrug resistant bacteria, which could eventually be treated through synthetic biology solutions.

During the event, we were able to share with the audience the concept of synthetic biology, how it is applied in Costa Rica and the possible use of bioengineered microorganisms as treatment. The response of the participants about the topic was positive; however, we were interested to know if they considered that a bioengineered probiotic as a therapeutic was a possible option in our healthcare system. Among the comments we received, doctors reaffirmed to us the importance of divulging this new kind of treatments, so that the public is more recipient of it and less scared about its side effects. In words of one of the doctors: “if you publish, communicate and socialize your treatment, then it is easier for us to suggest it as a therapeutic to patients that have heard about it, in contrast with those who have not”.

Hand in hand with the above, another engagement activity we did in the Dr. Raúl Blanco Cervantes Hospital consisted in providing the information of the booklet to various patients and companions. As this hospital is specialized in the elderly, we were able to share about antibiotic resistance with a vulnerable public. Must of patients were really interested on the topic and they took their time to read the information provided and ask us questions. Therefore, in the hospitals we were able to bring synthetic biology as an alternative closer to the Costa Rican healthcare system and final beneficiaries.

Isolation room from Raul Blanco Cervantes Hospital

Academic Talks

Costa Rica is recognized as one of the leading countries in terms of education in Latin America. However, for Costa Rican educational policy and practice there’s a lot to improve in the field of science and technology. Within it, synthetic biology is undoubtedly an unexplored topic in Costa Rican education.

Therefore, our team gave the booklet and talked to high school and undergrad students who aren’t able to learn of it in order place. We introduced basic concepts of synthetic biology such as genetic modification, recombinant proteins, domain fusions, among others. We also explained our project diffEASY, raised awareness about the situation of Costa Rican politics regulation and mainly, motivated them to don’t lose their interest to understand their surroundings.

Talk at the "Colegio Madre del Divino Pastor"

Press Release

Our booklet aimed to engage synthetic biology with Costa Rican society too, considering the beliefs of general population, some of them based on disinformation. Therefore, we reached different press media from our country to help us inform a larger public. It is important to emphasize that this kind of involvement with general public is key in the improvement of an informed and critical society, in order to create awareness of the possibilities with GMOs and their limitations.

Fortunately, we were featured in multiple press releases, including social media, radio and television. Notably, TV interviews were hosted in the main TV news channels of the country. Also, thanks to Kantar Media Ibope, software for press monitoring used by ITCR, here we show you a summary with all the press publications and their reach, which had a total of 204 373 people.

Our booklet design

(Hover mouse over to stop)

Antibiotic resistance: A global problem

Since we were brainstorming about possible problems to be addressed, we quickly (not so much) stumbled upon the issue of antibiotic resistance. This phenomenon is expected to provoke up to 10 million annual deaths by 2050 (O'Neill, 2014), possibly the first death cause worldwide. This has lead the United Nations to declare antibiotic resistance as one of the greatest threats to global public health.

Resistant bacterial infections: Choosing our project aim

Antibiotic resistance is an exponential growing problem around the world and it has a very serious social impact. Looking for a solution to this problem we focused on a gastrointestinal pathogen, Clostridioides difficile. This bacteria infected patients in 21 of the 29 hospitals of Costa Rica from 2011-2014. Even one of our team members has suffered from this illness.

Problems:

Awareness for antibiotic resistance is lacking

There is a worldwide lack of knowledge on the subject of microbial resistance to antibiotics and Costa Rica is not the exception. Globally, the main cause of this problem is the misuse of antibiotics, leading to the survival of some resistant bacteria, able to spread again. Also, the bad waste management of these drugs contributes to increase resistant bacteria. This bacteria can later transfer their resistance to human microbiota (van Rijn et al., 2019).

Research is being conducted to discover new antibiotics. However, only two new antibiotic classes (lipopeptides and oxazolidinones) have been developed and approved by international drug agencies (US Food and Drug Administration and European Medicines Agency) in the last three decades (Tacconelli et al., 2018). The field of antibiotics is not lucrative enough for pharmaceutical companies and newly discovered compounds remain similar in function to current antibiotics. As a result, only a few large companies such as GlaxoSmithKline, Novartis, Merck and Roche are still actively engaged in antibiotic research and development (Jackson, Czaplewski & Piddock, 2018).

During our problems exploration we realized antibiotic resistance consists on the two problems mentioned above. Therefore, we decided to go out the lab to help create awareness on antibiotic resistance in our country and prove the prevalence of antibiotic resistance bacteria using the agar antibiotic resistance test.

Larger agar antibiotic resistance test

We went to the streets to have a closer encounter with people. In total we sampled 10 different places of Costa Rica: La Agonía Park in Alajuela, Central Park in Heredia, Central Park in Cartago and seven different places in San Jose (Central Park, El Mercado Central, La Sabana Metropolitan Park, France Park and the buses stations from Limón, Puntarenas and Liberia). We talked to 100 Costa Ricans, explained them a little bit of our problem and sampled their mouth with sterile swabs and following the National Health Ministry regulations. Samples were grown in petri dishes supplemented with amoxicillin (antibiotic most commonly used in Costa Rica) for 24h at 37 °C.

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References

Jackson, N., Czaplewski, L., & Piddock, L. J. (2018). Discovery and development of new antibacterial drugs: learning from experience?. Journal of Antimicrobial Chemotherapy, 73(6), 1452-1459.

O’Neill, J. (2014). Antimicrobial resistance. Tackling a Crisis for the Health and Wealth of Nations.

Tacconelli, E., Carrara, E., Savoldi, A., Harbarth, S., Mendelson, M., Monnet, D. L., ... & Ouellette, M. (2018). Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis. The Lancet Infectious Diseases, 18(3), 318-327.

van Rijn, M., Haverkate, M., Achterberg, P., & Timen, A. (2019). The public uptake of information about antibiotic resistance in the Netherlands. Public Understanding of Science, 28(4), 486-503.

"La ciencia es lo que entendemos lo suficientemente bien como para explicarle a una computadora. Arte es todo lo demás que hacemos".

— Donald Knuth.