Team:Moscow

About our project
We are the Moscow iGEM team. The project that we decided to create is associated with ticks, which are carriers of various diseases that have serious consequences, for example, borreliosis. Ticks are very common in Russia, as well as in general in the middle zone of Eurasia. After being bitten by an infected tick, it is necessary to start treatment as quickly as you can. Taking this into account, the question of the rapid detection of infected ticks arises. This is the main part of our project — creating a detection system of infected ticks.
LYME EXPRESS on the spot
Project plan
Step 1
Bioinformatics
The first part of the LymeExpress project is Bioinformatics. It consists of searching for the conserved genome regions between different species of Borrelia and metagenomic analysis of the Ixodes microbiome for possible interference with the biosensor targets from Borrelia sp. Then the molecular type of biosensor targets will be provided.
Step 2
Biosensor Development
In this part of the project the targeting system (CRISPR-Cas) and the detection system will be determined. In parallel, computer modeling of the biosensor work will be carried out. This step also contains quality check and testing.
Step 3
Device development
The last step of LymeExpress project is creating a portable spectrophotometer. Then combination of the biosensor and device will be checked and tested.
Biosensor
LYME EXPRESS advantages
MSU
MSU Biological Faculty
MIPT
Sechenov University
AESC MSU
Helicon
Haxus
Nanolek
SkyGen
Qiagen
Evrogen
Invitro
Chroma Technology
Twist Bioscience
Integrated DNA Technologies
New England BioLabs
Unstoppable Technologies
BioSchool Piligrim
institute of fundamental medicine and biology