Team:Freiburg/Achievements

Achievements
human practices
  • Integrated expert opinions into our project
  • Engaged the public on science and synthetic biology
  • Implemented impressions from the industry and patented our ligands
in vivo
  • Optimized E.coli strain for improved D-AA incorporation
  • Assembled a toolbox for preparing and detecting D-AA
  • Established SPD5 droplets in E.coli
in silico
  • Enabled GROMACS modeling of N-formylated proteins
  • Created finDr, a novel software for D-peptide discovery
  • Demonstrated its potential by identification of PSMα3 binders
mipd
  • Discovered, verified and modeled promising inhibitors for PSMα3
  • Chemically synthesized active D-PSMα3 and other peptides
  • Validated findings in wet lab experiments