Difference between revisions of "Team:Calgary/Model"
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| + | <h1 class="page-title">Modelling</h1> | ||
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| + | <h1>Modelling</h1> | ||
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| − | <div class="col-lg-6 col-md-6 col-sm-12 col-xs-12 expand-on-hover" > <a target="blank" href="https://2019.igem.org/Team:Calgary/Model/ICARUS"> | + | |
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| − | + | <div class="col-lg-6 col-md-6 col-sm-12 col-xs-12 expand-on-hover"> | |
| − | + | <a target="blank" href="https://2019.igem.org/Team:Calgary/Model/ICARUS"> | |
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| + | <img src="https://static.igem.org/mediawiki/2019/9/9b/T--Calgary--newICARUS.png" width="28%" style="margin-left: auto; margin-right: auto; display: block;" /> | ||
| + | <div class="sources--cms"> | ||
| + | <h3 style="text-align:center">ICARUS - <i>Pheophorbide Production</i></h3> | ||
| + | <p style="text-align:center"><b>i</b>GEM <b>C</b>algary <b>A</b>ugmented <b>R</b>epulsion <b>U</b>niversal <b>S</b>pacer: <br />A spacer to his-purify proteins.</p> | ||
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| + | <div class="col-lg-6 col-md-6 col-sm-12 col-xs-12 expand-on-hover"> | ||
| + | <a target="blank" href="https://2019.igem.org/Team:Calgary/Model/EmulsionPrediction"> | ||
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| + | <img src="https://static.igem.org/mediawiki/2019/3/31/T--Calgary--ternaryPhaseGIF.gif" width="25%" style="margin-left: auto; margin-right: auto; display: block;" /> | ||
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| + | <h3 style="text-align:center">Emulsion Construction Prediction - <i>Emulsified Proteins</i></h3> | ||
| + | <p style="text-align:center">Using machine learning to predict phase of an emulsion at any composition.</p> | ||
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| − | <div class=" | + | <div class="col-lg-6 col-md-6 col-sm-12 col-xs-12 expand-on-hover"> |
| + | <a target="blank" href="https://2019.igem.org/Team:Calgary/Model/DirectedProteinModification"> | ||
| + | <div class="container__sources"> | ||
| + | <img src="https://static.igem.org/mediawiki/2019/1/1b/T--Calgary--Tobeyfromtheoffice.png" width="60%" style="margin-left: auto; margin-right: auto; display: block;" /> | ||
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| + | <h3 style="text-align:center">Directed Protein Structure Modification - <i>modGIX</i></h3> | ||
| + | <p style="text-align:center">Using in silico dynamic simulations to perform informed modifications of amino acids in proteins. </p> | ||
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| + | <a target="blank" href="https://2019.igem.org/Team:Calgary/Model/InSilicoEmulsionSystemVerification"> | ||
| + | <div class="container__sources"> | ||
| + | <img src="https://static.igem.org/mediawiki/2019/d/d9/T--Calgary--WIKIDYNAMICS-Icon.png" width="29%" style="margin-left: auto; margin-right: auto; display: block;" /> | ||
| + | <div class="sources--cms"> | ||
| + | <h3 style="text-align:center">In Silico Emulsion System Verification - <i>6GIX</i></h3> | ||
| + | <p style="text-align:center">Verifying emulsified protein function and structure stability in antagonistic solvents. </p> | ||
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| − | + | <p style="margin-bottom:5vh">With a strong dry lab team, making informed decisions based on in silico data was easier, but modelling became a necessity for the iGEM Calgary team as many results would not have been possible were it not for successful modelling of wet lab components.</p> | |
| − | <p style="margin-bottom:5vh">With a strong dry lab team, making informed decisions based on in silico data was easier, but modelling became a necessity for the iGEM Calgary team as many results would not have been possible were it not for successful modelling of wet lab components.</p> | + | <img src="https://static.igem.org/mediawiki/2019/7/72/T--Calgary--MODFLOW.svg" width="66%" style="margin-left: auto; margin-right: auto; display: block;" /> |
| − | <img src="https://static.igem.org/mediawiki/2019/7/72/T--Calgary--MODFLOW.svg" width="66%" style="margin-left: auto; margin-right: auto; display: block;"/> | + | <p>The workflow of iGEM's Calgary modelling team followed a natural workflow towards making informed decisions. Whenever problems were found, modelling tried to find a way to help. Each created model was vetted by the experienced members of wetlab for its validity. These could then be reworked, or implemented in the lab. In the latter, the data could then be sent to reinforce the model.</p> |
| − | <p>The workflow of iGEM's Calgary modelling team followed a natural workflow towards making informed decisions. Whenever problems were found, modelling tried to find a way to help. Each created model was vetted by the experienced members of wetlab for its validity. These could then be reworked, or implemented in the lab. In the latter, the data could then be sent to reinforce the model.</p> | + | <p style="margin-bottom:5vh">An examplar of this model is the <a href="https://2019.igem.org/Team:Calgary/Model/EmulsionPrediction" target="_blank">Emulsion Construction Prediction model</a>which was developed using wet lab data, using the data to predict good constructions, then further data was collected in those zones, and so on, until we had a model that could predict, with extremely high confidence, the phase constructed with given parameters. This model was invaluable in <a href="https://2019.igem.org/Team:Calgary/Demonstrate" target="_blank">Demonstrating our proteins</a>function in emulsions as many emulsion phases would denature our proteins.</p> |
| − | <p style="margin-bottom:5vh">An examplar of this model is the <a href="https://2019.igem.org/Team:Calgary/Model/EmulsionPrediction" target="_blank">Emulsion Construction Prediction model</a>which was developed using wet lab data, using the data to predict good constructions, then further data was collected in those zones, and so on, until we had a model that could predict, with extremely high confidence, the phase constructed with given parameters. This model was invaluable in <a href="https://2019.igem.org/Team:Calgary/Demonstrate" target="_blank">Demonstrating our proteins</a>function in emulsions as many emulsion phases would denature our proteins.</p> </div> | + | </div> |
| + | </div> | ||
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Revision as of 04:06, 21 October 2019
Section / Page
Modelling
With a strong dry lab team, making informed decisions based on in silico data was easier, but modelling became a necessity for the iGEM Calgary team as many results would not have been possible were it not for successful modelling of wet lab components.
The workflow of iGEM's Calgary modelling team followed a natural workflow towards making informed decisions. Whenever problems were found, modelling tried to find a way to help. Each created model was vetted by the experienced members of wetlab for its validity. These could then be reworked, or implemented in the lab. In the latter, the data could then be sent to reinforce the model.
An examplar of this model is the Emulsion Construction Prediction modelwhich was developed using wet lab data, using the data to predict good constructions, then further data was collected in those zones, and so on, until we had a model that could predict, with extremely high confidence, the phase constructed with given parameters. This model was invaluable in Demonstrating our proteinsfunction in emulsions as many emulsion phases would denature our proteins.
