Difference between revisions of "Team:Calgary/Model"

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<h2>Modelling</h2>
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<h1>Modelling</h1>
 
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                     <img src="https://static.igem.org/mediawiki/2019/9/9b/T--Calgary--newICARUS.png" width="28%" style="margin-left: auto; margin-right: auto; display: block;"/>
 
                     <img src="https://static.igem.org/mediawiki/2019/9/9b/T--Calgary--newICARUS.png" width="28%" style="margin-left: auto; margin-right: auto; display: block;"/>
 
                     <div class="sources--cms">
 
                     <div class="sources--cms">
                         <h3>ICARUS - <i>Pheophorbide Production</i></h3>
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                         <h3 style="text-align:center">ICARUS - <i>Pheophorbide Production</i></h3>
                         <p><b>i</b>GEM <b>C</b>algary <b>A</b>ugmented <b>R</b>epulsion <b>U</b>niversal <b>S</b>pacer: <br/>A spacer to his-purify proteins.</p>
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                         <p style="text-align:center"><b>i</b>GEM <b>C</b>algary <b>A</b>ugmented <b>R</b>epulsion <b>U</b>niversal <b>S</b>pacer: <br/>A spacer to his-purify proteins.</p>
 
                     </div>
 
                     </div>
  
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                     <img src="https://static.igem.org/mediawiki/2019/3/31/T--Calgary--ternaryPhaseGIF.gif" width="25%"style="margin-left: auto; margin-right: auto; display: block;"/>
 
                     <img src="https://static.igem.org/mediawiki/2019/3/31/T--Calgary--ternaryPhaseGIF.gif" width="25%"style="margin-left: auto; margin-right: auto; display: block;"/>
 
                     <div class="sources--cms">
 
                     <div class="sources--cms">
                         <h3>Emulsion Construction Prediction - <i>Emulsified Proteins</i></h3>
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                         <h3 style="text-align:center">Emulsion Construction Prediction - <i>Emulsified Proteins</i></h3>
                         <p>Using machine learning to predict phase of an emulsion at any composition.</p>
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                         <p style="text-align:center">Using machine learning to predict phase of an emulsion at any composition.</p>
 
                     </div>
 
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                     <img src="https://static.igem.org/mediawiki/2019/1/1b/T--Calgary--Tobeyfromtheoffice.png" width="60%"style="margin-left: auto; margin-right: auto; display: block;"/>
 
                     <img src="https://static.igem.org/mediawiki/2019/1/1b/T--Calgary--Tobeyfromtheoffice.png" width="60%"style="margin-left: auto; margin-right: auto; display: block;"/>
 
                     <div class="sources--cms">
 
                     <div class="sources--cms">
                         <h3>Directed Protein Structure Modification - <i>modGIX</i></h3>
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                         <h3 style="text-align:center">Directed Protein Structure Modification - <i>modGIX</i></h3>
                         <p>Using in silico dynamic simulations to perform informed modifications of amino acids in proteins. </p>
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                         <p style="text-align:center">Using in silico dynamic simulations to perform informed modifications of amino acids in proteins. </p>
 
                     </div>
 
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                     <img src="https://static.igem.org/mediawiki/2019/d/d9/T--Calgary--WIKIDYNAMICS-Icon.png" width="29%"style="margin-left: auto; margin-right: auto; display: block;"/>
 
                     <img src="https://static.igem.org/mediawiki/2019/d/d9/T--Calgary--WIKIDYNAMICS-Icon.png" width="29%"style="margin-left: auto; margin-right: auto; display: block;"/>
 
                     <div class="sources--cms">
 
                     <div class="sources--cms">
                         <h3>In Silico Emulsion System Verification - <i>6GIX</i></h3>
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                         <h3 style="text-align:center">In Silico Emulsion System Verification - <i>6GIX</i></h3>
                         <p>Verifying emulsified protein function and structure stability in antagonistic solvents. </p>
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                         <p style="text-align:center">Verifying emulsified protein function and structure stability in antagonistic solvents. </p>
 
                     </div>
 
                     </div>
  

Revision as of 04:54, 20 October 2019

Modelling

Blurb about why modelling is so important

The workflow of iGEM's Calgary modelling team followed a natural workflow towards making informed decisions. Whenever problems were found, modelling tried to find a way to help. Each created model was vetted by the experienced members of wetlab for its validity. These could then be reworked, or implemented in the lab. In the latter, the data could then be sent to reinforce the model.

An examplar of this model is the Emulsion Construction Prediction modelwhich was developed using wet lab data, using the data to predict good constructions, then further data was collected in those zones, and so on, until we had a model that could predict, with extremely high confidence, the phase constructed with given parameters. This model was invaluable in Demonstrating our proteinsfunction in emulsions as many emulsion phases would denature our proteins.