Team:SJTU-BioX-Shanghai

Project

Description

• Off-Target Incident
• Inspiration
• Proposal
• Birth of Mulan
• Mulan & Society

Design

• Overview
• Real-time Detect
• Deferred Detect
• Biostorage

Result

• Real-time Detect
• Deferred Detect
• Biostorage

Safety

• Summary
• General Wet-lab Safety
• Project Specific Safety
• Future Application Risks

Demonstrate

Gene Circuit

Model

Overview

• CRISPR Principle
• Biological Origin
• Why We Model
• Target-recognition Model
• Our Models

General

• Background
• Cleavage Probability
• Summary

Mismatch Predict

• Single-mismatch
• Multi-mismatch

Codec

• Overview
• Introduction
• Redundancy
• Encoding

Software

• Off-Target Predictor
• Bio-stroage Codec

Wet-Lab

Parts

• Basic Parts
• Composite parts
• Collection
• Improvement
• Characterization

Measurement

• Fluorescence Standard Curve
• Particle Standard Curve

Notebook

• Off-Targeting
• Transcript Activation
• Bio-Storage

Protocols

H.P.

Overview

Laboratory

Market

• Demand Side
• Supply Side

Public

• Summary
• Questionnaire
• Interview
• Videos
• Conclusion

Humanity

• Philosophical
• Legal

Education

• Summary
• Footprint

Team

Members

• Students
• Instructors
• Advisers

Collaborations

• Introduction
• High School
• Undergraduate
• Community
• Interlab

Attributions

• Time Line
• Team Attributions
• External Support

Medals »

SJTU-BioX-Shanghai

Making CRISPR safer-- CRISPR off-target detection

Project Design

Three ways of detecting off- target incidents

Wet-Lab Parts

New bio- brick collections

Human Practice

"L-M-P-H-E", a new model of human practices

Model Overview

Explore our Off- target detection and biostorage codec methods

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