Team:Lund
We at iGEM Lund 2019 have genetically modifying a probiotic bacteria - E. coli Nissle 1917 (EcN) - to increase its ability to absorb and accumulate lead and arsenic. Lead and arsenic, among many other toxic metals are generating problems across the globe, especially in countries with poor water infrastructure such as Bangladesh and Argentina. Our product implements PRObiotics to DEACCumulate toxic metals from your body, hence PRODEACC. Read more or watch the video below!
Designing our project
Do you want to know how we designed our composite parts and experiments? Head over to our Project Design!
Results
When E coli Nissle is tranformed with our constructs they can reduce the lead concentration by 40%, or the arsenic concentration by 20%! Click here to read the full results!
Integrated Human Practices
Our efforts in human practices has helped us design our project and realize what needs to be done to make PRODEACC a reality. Read more...
Public Engagement
We've had so much fun interacting with others and engaging the public. Read all about it here!
Our ethics project - SynthEthics
Throughout our project we've been interested in the ethical concerns of synthetic biology and genetic engineering, which spawned SynthEthics! Read more...
Mathematical Models
By modelling the bodies uptake of metals we have investigated the effectiveness of PRODEACC. Our mathematical model can be used to estimate what effect PRODEACC will have on our bodies. Below is a representtion of the bioaccumulation of lead, without and with PRODEACC projected over 8 years. Read more...
Blog
To get students interested in science and synthetic biology we’ve written articles on interesting subjects and published them on our blog. Would you like a good read?.
Team
iGEM Lund 2019 is consistent of 11 members from around the globe. We also wish to praise our two main mentors during this project: Nelida Leiva Eriksson and Johan Svensson Bonde. Read more about the team-members here.
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