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Parts Overview
CASPRE's Parts
Our team generated three basic parts and two composite parts this year. On top of that, we made significant improvements on one of the parts that we made last year.
The collection as a whole paves the way for rapid diagnosis of recessive alleles for cystic fibrosis in patients, whereas the improved part improves our existing methods for diagnosing the recessive sickle cell anemia allele.
iGEM CMU-Q BioBrick List
Part Number | Basic Or Composite | Description | Type | Designer | Lengths |
---|---|---|---|---|---|
BBa_K2961000 | Basic | CFTR Mutant Gene Segment (rs75389940_G) | DNA | iGEM CMUQ | 24bps |
BBa_K2961001 | Basic | CFTR Wildtype gene segment | DNA | iGEM CMUQ | 24bps |
BBa_K2961003 | Basic | gRNA / crRNA fixed-loop repeat for Cpf1 / Cas12a | RNA | iGEM CMUQ | 21bps |
BBa_K2961004 | Composite | gRNA for Cystic Fibrosis SNP targeting of Cas12a / Cpf1 (rs75389940_G) | RNA | iGEM CMUQ | 45bps |
BBa_K2961005 | Composite | gRNA for Cystic Fibrosis Wildtype gene targeting of Cas12a / Cpf1 | RNA | iGEM CMUQ | 45bps |
BBa_K2961006 | Basic | Template DNA sequence encoding for HBB rs334 mutation (A to T) in humans (improves on --> BBa_K2872881) | DNA | iGEM CMUQ | 210bps |