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"In the iGEM registry, less than 5 % of the registered promoters are from filamentous fungi.", | "In the iGEM registry, less than 5 % of the registered promoters are from filamentous fungi.", | ||
− | "Aspergillus spp. are responsible for the production of > | + | "<i>Aspergillus</i> spp. are responsible for the production of >30 % of all industrially produced enzymes [3]", |
"There are approximately 5.1 million different species of filamentous fungi [1]", | "There are approximately 5.1 million different species of filamentous fungi [1]", | ||
"Half of the industrially manufactured enzymes are produced by filamentous fungi [3].", | "Half of the industrially manufactured enzymes are produced by filamentous fungi [3].", | ||
− | "Aspergillus niger produces >99 % of all citric acid sold [2].", | + | "<i>Aspergillus niger</i> produces >99 % of all citric acid sold [2].", |
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fact_2="There are approximately 5.1 million different species of filamentous fungi."; | fact_2="There are approximately 5.1 million different species of filamentous fungi."; | ||
− | fact_3="Aspergillus niger produces >99% of all citric acid sold"; | + | fact_3="<i>Aspergillus niger</i> produces >99% of all citric acid sold"; |
fact_4="Half of the industrially manufactured enzymes are produced by filamentous fungi."; | fact_4="Half of the industrially manufactured enzymes are produced by filamentous fungi."; | ||
− | fact_5="Aspergillus spp. are responsible for the production of > 30% of all industrially produced enzymes."; | + | fact_5="Aspergillus spp. are responsible for the production of >30% of all industrially produced enzymes."; |
− | fact_6="The total annual revenue from enzymes produced by Aspergillus spp. is 480 mio USD per year [3]."; | + | fact_6="The total annual revenue from enzymes produced by <i>Aspergillus</i> spp. is 480 mio USD per year [3]."; |
fact_7="In the iGEM registry, less than 5% of the registered promoters are from filamentous fungi"; | fact_7="In the iGEM registry, less than 5% of the registered promoters are from filamentous fungi"; |
Revision as of 16:03, 21 October 2019
Our Library
Therefore we are creating a library of synthetic fungal promoters that are: predictable, robust, and scalable. These were designed using special software based on sequence conservation. In the design we have included feedback from relevant companies and scientists, meaning that the promoters are useful in both industry and academia.
The total annual revenue from enzymes produced by Aspergillus spp. is 480 mio USD per year [3].