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Revision as of 17:11, 20 October 2019

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What's VVC?

Vulvovaginal candidiasis (VVC) has been recognized as one of the most common infections in female reproductive organs.

VVC is mainly caused by Candida albicans (C. albicans), accounting for more than 85% of the incidence, which seriously affects the normal life of women.

70-75%

of women will suffer from VVC at least once in thier life time.

40-45%

will have 2 or more episodes.

Symptoms

Abnormal Vaginal Discharge

Genital and Vaginal burning

External Dysuria

Itching and Redness

How to Treat?

Till now, as a commonly used antifungal drug for VVC treatment, vaginal azole preparations can inhibit the growth of C. albicans, or kill them directly.

HOWEVER

The widespread usage of antifungal drugs and the increase in the number of fungal infections have led to the emergence of drug resistance, even the repeated recurrence to VVC of patients.

But, there is a

New Therapy for Vulvovaginal Candidasis:

Our Systems

Sensing System

Sensing system can sense C. albicans and activate the downstream gene.

Theraputic System

LL37 can perforate the cell membrane of C.albicans.

The β-1,3-glucanase can disrupt the
biofilm of C. albicans.

BDSF can inhibit hypha formation
by C. albicans.

Msp1 can destabilize the hyphae of C. albicans.

Practices Facilitated Our Project

Initially, we brainstormed to decide our project. We came up with three projects: General White Resistance, Vaginitis Treatment and Plant Resistance Improvement
After attending the women's lecture, we decided to study the method of treating vaginitis and confirmed VVC through questionnaire collection.
After interviewing patients and doctors, we learned about the current problems in the treatment of VVC and brainstormed the project 1.0.
After having brainstormed project 1.0.We interviewed professors give us suggestions to improve our project 1.0 and obtained project 2.0.
We interviewed experts for a comprehensive assessment of our project. To make project practical, we interviewed ethical experts, pharmacies and pharmacies.

Model

Our project is well conducted by Model in terms of experiments and prediction of future application. Our Model is constituted with

1. C. albicans Sensing Model
2. Gene Concentration Prediction Model
3. Market Prediction Model

In Case You Missed Them:

Background

Design

Result

Our Parts

Practices

Medals