Difference between revisions of "Team:DTU-Denmark"

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  "Molds are not only found on spoiled foods but are actually used to produce many everyday items such as enzymes for washing powder food additives.",
 
  "Molds are not only found on spoiled foods but are actually used to produce many everyday items such as enzymes for washing powder food additives.",
 
    
 
    
−
  "In the iGEM registry, less than 5 % of the registered promoters are from filamentous fungi.",
+
  "In the iGEM registry, less than 5% of the registered promoters are from filamentous fungi.",
 
 
 
 
−
  "<i>Aspergillus</i> spp. are responsible for the production of > 30% of all industrially produced enzymes [3]",
+
  "<i>Aspergillus</i> spp. are responsible for the production of >30% of all industrially produced enzymes [3]",
 
    
 
    
 
   "There are approximately 5.1 million different species of filamentous fungi [1]",
 
   "There are approximately 5.1 million different species of filamentous fungi [1]",

Revision as of 11:38, 20 October 2019

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A World of Biotechnology

Many everyday products are produced using microorganisms such as fungi. The production of these products is regulated by small DNA sequences called promoters. These are necessary tools to optimize the yield of the desired product and minimize the yield of others.

Promoters

These promoters work as regulators for gene expression. Think of it as a gear in a car. Some gears make the car go fast, and others lower the speed. This is done by controlling the transcription of a gene, as it determines the strength at which the RNA polymerase can bind.

Our Library

Therefore we are creating a library of synthetic fungal promoters that are: predictable, robust, and scalable. These were designed using special software based on sequence conservation. In the design we have included feedback from relevant companies and scientists, meaning that the promoters are useful in both industry and academia.

Did you know?

The total annual revenue from enzymes produced by Aspergillus spp. is 480 mio USD per year [3].

A small step for man, a giant LEAP for iGEM

The logos of our three biggest supporters, DTU Blue Dot, Novo Nordisk fonden and Otto Mønsted fonden The logos of all of our sponsors, DTU, BioNordica, Eurofins Genomics, Qiagen, NEB New England biolabs, IDT Integrated DNA technologies and Twist bioscience