Difference between revisions of "Team:Jilin China"

 
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{{:Team:Jilin_China/partofBs_CSS}}
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{{:Team:Jilin_China/fontawesome_CSS}}
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{{:Team:Jilin_China/Nav_Cont}}
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{{:Team:Jilin_China/Main_Cont_CSS}}
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{{:Team:Jilin_China/Home_cont}}
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<html>
  
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</html>
 
<html>
 
<html>
<div>we love mediawi**!</div>
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<meta name="viewport" content="width=device-width, initial-scale=1, user-scalable=no">
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<script>//coupleColor = [ "#fff","#485"];
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(function(){
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  $("#HQ_page").addClass("luanhaixin");
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$("#HQ_page").removeAttr("id");
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})();
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var HXT=1;
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</script>
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<style>
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 +
/*This Part for Cleaning Default Template*/
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 +
#home_logo, #sideMenu { display:none; }
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html{width:100%;height:100%;background:white; list-style:none;}
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#globalWrapper,#HQ_page,#bodyContent,#mw-content-text{height:100%;}
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#sideMenu, #top_title, .patrollink  {display:none;}
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#content { margin-left:0px; margin-top:-7px; padding:0px; width:100%;height:100%;}
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body {background-color:white;height:100%;}
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#bodyContent h1, #bodyContent h2, #bodyContent h3, #bodyContent h4, #bodyContent h5 { margin-bottom: 0px; }
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@font-face{
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  font-family: 'DIN B';
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  font-weight: normal;
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@font-face{
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  font-family: 'DIN B';
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  font-weight: Bold;
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}
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h1,h2,h3,h4,h5,p{
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  font-family:'DIN B','DIN Medium';
 +
}
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h1, h2, h3, h4, h5, h6{
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padding: 1rem 0 !important;
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p{
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margin:0 !important;
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article,
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aside,
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canvas,
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details,
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embed,
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figure,
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figcaption,
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footer,
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header,
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hgroup,
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menu,
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nav,
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output,
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section,
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summary,
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time,
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audio,
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video {
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body{
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background-color:#fff !important;
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display:block !important;
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overflow-x:hidden !important;
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height:100% !important;
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display:block !important;
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#mw-content-text{
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height:100% !important;
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display:block !important;
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position:relative !important;
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height:100% !important;
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display:block !important;
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position:relative !important;
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.s1 p{
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float:left;
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section{
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@media (min-width:1000px) {
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section{
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margin-right: auto;
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.picCont .pic{
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overflow-y: hidden;
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background-size: 100% auto;
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background-repeat: no-repeat;
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.picCont .pic .picinner {
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height: 10%;
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width: 100%;
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background-color: rgba(0,227,202,0.79);
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position: relative;
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.picCont .picword{
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float: left;
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width: 100%;
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text-align: center;
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height: 100%;
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.tableCont  {
 +
display: block;
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height: auto;
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margin: 0 auto;
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width: 85%;
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overflow-x: hidden;
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overflow-y: hidden;
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}
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.tableCont table {
 +
height: auto;
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display: block;
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border-collapse: collapse;
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position: relative;
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float: left;
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text-align: center;
 +
margin-top: 30px;
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}
 +
.tableCont table tbody {
 +
display: block;
 +
width: auto;
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height: auto;
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.tableCont .table .tableinner {
 +
height: 39px;
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width: 100%;
 +
font-size: 18px;
 +
line-height: 31px;
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}
 +
.tableCont table tbody tr:nth-child(2n)  {
 +
background-color: rgba(212,234,249,1.00);
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}
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.tableCont table tbody tr:nth-child(2n+1)  {
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background-color: rgba(220,239,252,1.00);
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}
 +
.tableCont table tbody tr:first-child {
 +
background-color: rgba(159,217,255,1.00);
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}
 +
 
 +
tbody td {
 +
border: 1px solid rgba(64,137,251,1.00);
 +
width: 1000px;
 +
height: 37px;
 +
}
 +
 
 +
 
 +
#top_title{
 +
    display: none;
 +
 
 +
}
 +
#content{
 +
width:100%;
 +
margin: 00;
 +
padding:00;
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}
 +
 
 +
 
 +
</style>
 +
<!--屏幕内容第一条 导航栏 -->
 +
 
 +
  <!--this part for the home page content. with built-in css-->
 +
<style>
 +
 +
/*Body Content*/
 +
section{
 +
width:100%;
 +
min-height:5rem;
 +
border:0px red solid;
 +
box-sizing:border-box;
 +
padding:3vw 7.5vw 6.5vw;
 +
}
 +
section h1{
 +
font-size: 2.8rem !important;
 +
/*font-family: 'DIN Condensed';*/
 +
}
 +
section h1.bg-white{
 +
color: rgba(255,83,83,1) !important;
 +
}
 +
section h2{
 +
font-size: 2rem !important;
 +
/*font-family: 'DIN Condensed';*/
 +
}
 +
 +
section.left .text{
 +
float: left !important;
 +
}
 +
section.right .text{
 +
float: right !important;
 +
}
 +
section.right .text *{
 +
float: right !important;
 +
}
 +
section.right .text h1{
 +
text-align: left !important;
 +
}
 +
 
 +
 
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.button:hover{
 +
box-shadow: 0.3rem 0 1rem rgba(0,0,0,0.3);
 +
transition: all 0.3s ease;
 +
background: rgba(255,201,230,1);
 +
}
 +
.button a{
 +
display: block;
 +
color: rgba(138,0,0,1);
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}
 +
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.button.colored{
 +
/*background: white;*/
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color: rgba(138,0,0,1);
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}
 +
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.clear{
 +
clear: both;
 +
}
 +
.s0{
 +
height:80%;
 +
background:rgba(255,0,90,0.7);
 +
overflow: hidden;
 +
z-index: 1;
 +
position:relative;
 +
}
 +
.s0 .title{
 +
position: relative;
 +
width: 50%;
 +
height: 100%;
 +
}
 +
.s0 .title img{
 +
position: absolute;
 +
bottom: 5vh;
 +
left:8vw;
 +
}
 +
.s0 .rose-background{
 +
background: url(https://static.igem.org/mediawiki/2019/f/fe/T--Jilin_China--Main--Rose.svg) no-repeat;
 +
background-size: contain;
 +
position: absolute;
 +
right:3vw;
 +
bottom:-25vw;
 +
transform: rotate(-19.9deg);
 +
filter: blur(10px) brightness(0.7);
 +
opacity: 0.3;
 +
width: 50vw;
 +
height:75vw;
 +
}
 +
 +
.s1{
 +
background: white;
 +
}
 +
/*对于内容相关的CSS使用内容相关Class,对于与顺序相关的使用 .s[num]*/
 +
.introduction .text{
 +
width:100%;
 +
 +
background-size: auto 75%;
 +
background-position: 90% calc(50% + 1.25rem);
 +
}
 +
 +
 +
 +
 +
.symptom .digits .digit{
 +
font-size:5.5vw;
 +
margin:0;
 +
}
 +
.symptom .digits .explain{
 +
margin:0 0 3vw !important;
 +
                        border:0px;
 +
}
 +
 +
.symptom .small-bg .image{
 +
width: 44%;
 +
padding: 0 5vw;
 +
margin:0 auto;
 +
box-sizing: border-box;
 +
}
 +
.symptom .small-bg .image img{
 +
width: 100%;
 +
text-align: center;
 +
margin: 0 auto;
 +
}
 +
.s2 .text{
 +
width: 100%;
 +
text-align: center;
 +
font-size:2vw;
 +
}
 +
 +
 +
 
 +
 
 +
 +
 +
 +
.s4{
 +
background: rgba(255,0,90,0.1);
 +
min-height: 34vh;
 +
z-index: -1;
 +
position: relative;
 +
}
 +
 +
 +
.s5{
 +
background: white;
 +
padding: 3vw 7.5vw;
 +
}
 +
.reverse p{
 +
color: rgba(199,0,0,1);
 +
margin:0;
 +
}
 +
 +
 +
.s6{
 +
background: rgba(255,0,99,.5);
 +
}
 +
.our-system{
 +
color: rgba(138,0,0,1);
 +
text-align: center;
 +
}
 +
 +
.our-system .theraputic{
 +
width: 100%;
 +
}
 +
 +
 
 +
.hp{
 +
background: white;
 +
text-align: center;
 +
position: relative;
 +
padding-bottom: 5vw;
 +
 
 +
}
 +
.hp h1{
 +
text-align: center;
 +
}
 +
 +
 +
 
 +
.model h1{
 +
position: relative;
 +
text-align: center;
 +
z-index: 1;
 +
}
 +
 
 +
@keyframes swirling {
 +
0%{
 +
background-position: 48% 50%;
 +
/*transform: rotate(0deg);*/
 +
}
 +
100%{
 +
background-position: 52% 50%;
 +
/*transform: rotate(360deg);*/
 +
}
 +
}
 +
 +
.more h1{
 +
font-size: 3rem;
 +
color: rgba(119,0,0,1);
 +
}
 +
.more .bottons{
 +
width: 100%;
 +
 +
}
 +
.more .botton{
 +
float: left;
 +
width: calc(33% - 2rem);
 +
margin: 1rem;
 +
height: 20vw;
 +
background: rgba(255,201,230,1);
 +
transition: 0.3s all ease;
 +
}
 +
.more .botton:hover {
 +
background: rgba(255,201,230,0.3);
 +
transition: 0.3s all ease;
 +
}
 +
.more .botton p{
 +
margin: 0;
 +
line-height: 20vw;
 +
text-align: center;
 +
font-size: 2.5vw;
 +
}
 +
</style>
 +
<section class="s0 banner" style="padding: 0 0;">
 +
<div class="title"><img alt="" src="https://static.igem.org/mediawiki/2019/f/f8/T--Jilin_China--Main--Words_-_Title.svg"/></div>
 +
<div class="rose-background">
 +
</div>
 +
<canvas id="maincabg" width="1920px" height="1080px" style="height:100%; height:auto;display: block;position: absolute;top: 0px; z-index: -1;"></canvas>
 +
</section>
 +
<section class="s1 introduction left">
 +
<div></div>
 +
<div class="text">
 +
<h1 class="bg-white">What's VVC?</h1>
 +
<p>Vulvovaginal candidiasis (VVC) has been recognized as one of the most common infections in female reproductive organs. </p>
 +
<p>VVC is mainly caused by <em>Candida albicans (C. albicans)</em>, accounting for more than 85% of the incidence, which seriously affects the normal life of women.</p>
 +
</div>
 +
<div class="clear"></div>
 +
</section>
 +
<section class="s2 symptom">
 +
<div class="digits">
 +
<p class="digit">70-75%</p>
 +
<p class="explain">of women will suffer from VVC at least once in thier life time.</p>
 +
<p class="digit">40-45%</p>
 +
<p class="explain">will have 2 or more episodes.</p>
 +
</div>
 +
<div class="small-bg">
 +
<div class="title">
 +
<h2 class="bg-colored">Symptoms</h2>
 +
</div>
 +
<div class="image">
 +
<img alt="" src="https://static.igem.org/mediawiki/2019/7/71/T--Jilin_China--Main--Girl_under_Period.svg" />
 +
</div>
 +
<div class="text">
 +
<p>Abnormal Vaginal Discharge</p>
 +
<p>Genital and Vaginal burning</p>
 +
<p>External Dysuria</p>
 +
<p>Itching and Redness</p>
 +
</div>
 +
 +
<div class="clear"></div>
 +
</div>
 +
</section>
 +
<section class="s3 current-treatment right">
 +
<div class="text">
 +
<h1 class="bg-white">How to Treat?</h1>
 +
<p>Till now, as a commonly used antifungal drug for VVC treatment, vaginal azole preparations can inhibit the growth of C. albicans, or kill them directly.</p>
 +
</div>
 +
<div class="clear"></div>
 +
</section>
 +
<div class="interspace">
 +
<p>HOWEVER</p>
 +
<div class="clear"></div>
 +
</div>
 +
<section class="s4 resistance right">
 +
<div class="text">
 +
<p id="ssss">The widespread usage of antifungal drugs and the increase in the number of fungal infections have led to the emergence of drug resistance, even the repeated recurrence to VVC of patients.</p>
 +
</div>
 +
<div class="clear"></div>
 +
<div class="button colored"><a href="https://2019.igem.org/Team:Jilin_China/Background"><p>Learn More about The Background</p></a></div>
 +
<div class="clear"></div>
 +
</section>
 +
<section class="s5 reverse">
 +
<p>But, there is a</p>
 +
<p>New Therapy for Vulvovaginal Candidasis:</p>
 +
<div class="clear"></div>
 +
</section>
 +
<section class="s6 our-system">
 +
<h1>Our Systems</h1>
 +
<div class="sensing">
 +
<h2>Sensing System</h2>
 +
<p style="margin-bottom:30px;margin-top:30px;  ">Sensing system can sense C. albicans and activate the downstream gene.</p >
 +
<img alt="" src="https://static.igem.org/mediawiki/2019/5/56/T--Jilin_China--Main--Words_-_Sensing_System.svg" />
 +
<p></p>
 +
</div>
 +
 +
 
 +
<div class="theraputic">
 +
<h2>Therapeutic System</h2>
 +
<div>
 +
<div class="effector1"><p>LL-37 can perforate the cell membrane of C. albicans.</p><img alt="" src="https://static.igem.org/mediawiki/2019/2/2e/T--Jilin_China--Main--LL37.svg"/></div>
 +
<div class="effector2"><p>The β-1,3-glucanase can disrupt the </br>biofilm of C. albicans.</p><img alt="" src="https://static.igem.org/mediawiki/2019/3/32/T--Jilin_China--Main--beta-1%EF%BC%8C3-glu.svg"/></div>
 +
<div class="effector3"><p>BDSF can inhibit hypha formation </br>by C. albicans.</p><img alt="" src="https://static.igem.org/mediawiki/2019/e/ed/T--Jilin_China--Main--BDSF.svg"/></div>
 +
<div class="effector4"><p>Msp1 can destabilize the hyphae of C. albicans.</p><img alt="" src="https://static.igem.org/mediawiki/2019/c/cc/T--Jilin_China--Main--Msp1.svg"/></div>
 +
</div>
 +
</div>
 +
<div class="clear"></div>
 +
<div class="button colored"><a href="https://2019.igem.org/Team:Jilin_China/Design"><p>Learn More about Our Design</p></a></div>
 +
<div class="clear"></div>
 +
</section>
 +
<section class="s7 hp">
 +
 
 +
 
 +
 
 +
 
 +
 
 +
<h1 class="bg-white">Practices Facilitated Our Project</h1>
 +
 
 +
<div class="third_s">
 +
  <div id="third_1">
 +
<div style="padding: 7.5vw"><img src="https://static.igem.org/mediawiki/2019/b/bc/T--Jilin_China--HP--HP_Overview.svg" width="100%" style=" margin: 0 auto"></div>
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<h1 class="bg-white">Model</h1>
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<p>Our project is well conducted by Model in terms of experiments and prediction of future application. Our Model is constituted with</br></br>1. C. albicans Sensing Model</br>2. Gene Concentration Prediction Model</br>3. Market Prediction Model</p>
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<div class="button colored"><a href="https://2019.igem.org/Team:Jilin_China/Model"><p>Learn More about Our Model</p></a></div>
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<section class="s9 more">
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<h1>In Case You Missed Them:</h1>
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<div class="bottons">
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<div id="bbgd"  class="botton otr"><p>Background</p><a class="foota otr1" href="https://2019.igem.org/Team:Jilin_China/Background"></a></div>
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<div id="design" class="botton otr"><p>Design</p><a class="foota otr1" href="https://2019.igem.org/Team:Jilin_China/Design"></a></div>
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<div id="result" class="botton otr"><p>Result</p><a class="foota otr1" href="https://2019.igem.org/Result"></a></div>
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<div id="par" class="botton otr"><p>Parts</p><a class="foota otr1" href="https://2019.igem.org/Team:Jilin_China/Parts"></a></div>
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<div id="hpp" class="botton otr"><p>Practices</p><a class="foota otr1" href="https://2019.igem.org/Team:Jilin_China/Human_Practices"></a></div>
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<div id="medal" class="botton otr"><p>Medals</p><a class="foota otr1" href="https://2019.igem.org/Team:Jilin_China/Medals"></a></div>
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{{:Team:Jilin_China/foot_Cont}}

Latest revision as of 03:32, 22 October 2019

Team
Project
Lab
Model
Parts
HP
Judging
Home
Members
Collaborations
Attributtions
Background
Description
Design
Result
Demonstrate
Notebook
Protocols
Safety
Model
Our parts
Improvement
Measurement
Integrated
Engagement
Juding Form
Medals

What's VVC?

Vulvovaginal candidiasis (VVC) has been recognized as one of the most common infections in female reproductive organs.

VVC is mainly caused by Candida albicans (C. albicans), accounting for more than 85% of the incidence, which seriously affects the normal life of women.

70-75%

of women will suffer from VVC at least once in thier life time.

40-45%

will have 2 or more episodes.

Symptoms

Abnormal Vaginal Discharge

Genital and Vaginal burning

External Dysuria

Itching and Redness

How to Treat?

Till now, as a commonly used antifungal drug for VVC treatment, vaginal azole preparations can inhibit the growth of C. albicans, or kill them directly.

HOWEVER

The widespread usage of antifungal drugs and the increase in the number of fungal infections have led to the emergence of drug resistance, even the repeated recurrence to VVC of patients.

But, there is a

New Therapy for Vulvovaginal Candidasis:

Our Systems

Sensing System

Sensing system can sense C. albicans and activate the downstream gene.

Therapeutic System

LL-37 can perforate the cell membrane of C. albicans.

The β-1,3-glucanase can disrupt the
biofilm of C. albicans.

BDSF can inhibit hypha formation
by C. albicans.

Msp1 can destabilize the hyphae of C. albicans.

Practices Facilitated Our Project

Model

Our project is well conducted by Model in terms of experiments and prediction of future application. Our Model is constituted with

1. C. albicans Sensing Model
2. Gene Concentration Prediction Model
3. Market Prediction Model

In Case You Missed Them:

Background

Design

Result

Parts

Practices

Medals


CONTACT US
Jilin_China AT Outlook.com
Nation Engineering Labortory for
AIDS Vaccine
Comate Bioscience
Gen Script
TransGen Biotech
MathWorks
Jilin
University
School of Life Science
TAIMEI TECHNOLOGY
Git Hub
NEW ENGLAND BioLabs
Agilent
Technologies