<div class="t1inb"><div class="t1nb0"><img class="yilei" src="https://static.igem.org/mediawiki/2019/9/96/T--Jilin_China--Main--HP_Brain_Half.svg" width="60%" ></div><div class="t1nb1"><div class="t1nb11">Initially, we brainstormed to decide our project. We came up with three projects: General White Resistance, Vaginitis Treatment and Plant Resistance Improvement.</div></div></div>
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<div class="t1inb "><div class="t1nb0"><img class="erlei" class="imgdo" src="https://static.igem.org/mediawiki/2019/c/c7/T--Jilin_China--Main--HPwomen.svg" height="90%" ></div><div class="t1nb1 t1do"><div class="t1nb11">After attending the women's lecture, we decided to study the method of treating vaginitis and confirmed VVC through questionnaire collection.</div></div></div>
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<div class="t1inb"><div class="t1nb0"><img class="yilei" src="https://static.igem.org/mediawiki/2019/3/3a/T--Jilin_China--Main--HP_Brain_Full.svg" width="60%" ></div><div class="t1nb1"><div class="t1nb11">After interviewing patients and doctors, we learned about the current problems in the treatment of VVC and brainstormed the project 1.0.</div></div></div>
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<div class="t1inb "><div class="t1nb0"><img class="sanlei aha" src="https://static.igem.org/mediawiki/2019/5/5d/T--Jilin_China--Main--HP1.0.svg" width="45%" ></div><div class="t1nb1 t1do"><div class="t1nb11">After having brainstormed project 1.0, we interviewed professors gave us suggestions to improve our project 1.0 and obtained project 2.0.</div></div></div>
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<div class="t1inb"><div class="t1nb0"><img class="sanlei" src="https://static.igem.org/mediawiki/2019/7/72/T--Jilin_China--Main--HP2.0.svg" width="45%" ></div><div class="t1nb1"><div class="t1nb11"> We interviewed experts for a comprehensive assessment of our project. To make project practical, we interviewed ethical experts, pharmacies and pharmacies.</div></div></div>
Vulvovaginal candidiasis (VVC) has been recognized as one of the most common infections in female reproductive organs.
VVC is mainly caused by Candida albicans (C. albicans), accounting for more than 85% of the incidence, which seriously affects the normal life of women.
70-75%
of women will suffer from VVC at least once in thier life time.
40-45%
will have 2 or more episodes.
Symptoms
Abnormal Vaginal Discharge
Genital and Vaginal burning
External Dysuria
Itching and Redness
How to Treat?
Till now, as a commonly used antifungal drug for VVC treatment, vaginal azole preparations can inhibit the growth of C. albicans, or kill them directly.
HOWEVER
The widespread usage of antifungal drugs and the increase in the number of fungal infections have led to the emergence of drug resistance, even the repeated recurrence to VVC of patients.
Our project is well conducted by Model in terms of experiments and prediction of future application. Our Model is constituted with1. C. albicans Sensing Model2. Gene Concentration Prediction Model3. Market Prediction Model