Difference between revisions of "Team:DTU-Denmark/Human Practices"

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<h3>★  ALERT! </h3>
 
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<p>This page is used by the judges to evaluate your team for the <a href="https://2019.igem.org/Judging/Medals">medal criterion</a> or <a href="https://2019.igem.org/Judging/Awards"> award listed below</a>. </p>
 
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<p> Delete this box in order to be evaluated for this medal criterion and/or award. See more information at <a href="https://2019.igem.org/Judging/Pages_for_Awards"> Instructions for Pages for awards</a>.</p>
 
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<h1>Human Practices</h1>
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At iGEM we believe societal considerations should be upfront and integrated throughout the design and execution of synthetic biology projects. “Human Practices” refers to iGEM teams’ efforts to actively consider how the world affects their work and the work affects the world. Through your Human Practices activities, your team should demonstrate how you have thought carefully and creatively about whether your project is responsible and good for the world. We invite you to explore issues relating (but not limited) to the ethics, safety, security, and sustainability of your project, and to show how this exploration feeds back into your project purpose, design and execution.
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<p>For more information, please see the <a href="https://2019.igem.org/Human_Practices">Human Practices Hub</a>. There you will find:</p>
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<ul>
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<li> an <a href="https://2019.igem.org/Human_Practices/Introduction">introduction</a> to Human Practices at iGEM </li>
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<li>tips on <a href="https://2019.igem.org/Human_Practices/How_to_Succeed">how to succeed</a> including explanations of judging criteria and advice about how to conduct and document your Human Practices work</li>
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<li>descriptions of <a href="https://2019.igem.org/Human_Practices/Examples">exemplary work</a> to inspire you</li>
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<li>links to helpful <a href="https://2019.igem.org/Human_Practices/Resources">resources</a></li>
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<li>and more! </li>
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<img src="https://static.igem.org/mediawiki/2019/4/41/T--DTU-Denmark--hpheader.svg" title="As science affects the world, the world affects science. This page describes what this project is going to bring to the world, and what we have learned and used from others" style="margin-top:75px;max-width:70%;margin-right:auto; margin-left:auto;display: block;
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<p>On this page, your team should document all of your Human Practices work and activities. You should write about the Human Practices topics you considered in your project, document any activities you conducted to explore these topics (such as engaging with experts and stakeholders), describe why you took a particular approach (including referencing any work you built upon), and explain if and how you integrated takeaways from your Human Practices work back into your project purpose, design and/or execution. </p>
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<p>If your team has gone above and beyond in work related to safety, then you should document this work on your Safety wiki page and provide a description and link on this page. If your team has developed education and public engagement efforts that go beyond a focus on your particular project, and for which would like to nominate your team for the Best Education and Public Engagement Special Prize, you should document this work on your <a href="https://2019.igem.org/Team:DTU-Denmark/Public_Engagement">Education and Education wiki page</a> and provide a description and link here. </p>
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<h2>Safety</h2>
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The creation of a library of promoters may not be very applicable in the everyday life of most people, but the library can certainly have a great impact on many people’s lives. In determining how our project is good for the world, we looked to the <a target="_blank" href="https://sustainabledevelopment.un.org">UN’s Sustainable Development Goals (SDGs)</a>. <br>
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We have identified 5 main goals that our project contributes to. We call these our primary SDGs. Following this, we have further 2 goals that are affected by our efforts in the primary goals. </p>
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<p>The iGEM judges will review this page to assess whether you have met the Silver and/or Gold medal requirements based on the Integrated Human Practices criteria listed below. If you nominate your team for the <a href="https://2019.igem.org/Judging/Awards">Best Integrated Human Practices Special Prize</a> by filling out the corresponding field in the <a href="https://2019.igem.org/Judging/Judging_Form">judging form</a>, the judges will also review this page to consider your team for that prize.  
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<h2>Regarding the organism</h2>
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<p>As described in the <a target="_blank" href="https://2019.igem.org/Team:DTU-Denmark/Description">product</a>, filamentous fungi are important producers in the biotechnological industry and they form the base of our project.
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We have chosen to work with <i>Aspergillus niger</i> as it is an important production organism, and the tools required to genetically engineer it already exists. We have used the specific strain ATCC1015 [1].
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This <i>Aspergillus</i> strain is classified as Biosafety Level 1, which indicates means that it is safe to use and handle in the lab. In addition to this designation, we have performed a safety check-in, as spore-forming fungi are not directly in the <a target="_blank" href="https://2019.igem.org/Safety/White_List">whitelist</a>.
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<h3>Silver Medal Criterion #3</h3>
 
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<p>Convince the judges you have thought carefully and creatively about whether your work is responsible and good for the world. Document how you have investigated these issues, how you engaged with communities relevant to your goals, why you chose this approach, what you have learned, and the potential impact of your project’s success.  </p>
 
  
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<h2>Fermentation safety</h2>
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<p>During our project, we will be using larger-scale fermentations to verify our promoters. This introduces new challenges in safely handling our organism and the larger equipment.
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To the first point, <i>Aspergillus niger</i>, and many other filamentous fungi, the production of spores is dependent on external conditions of the fermentation.
  
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<h3>Gold Medal Criterion #1</h3>
 
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<p>Expand on your silver medal activity by demonstrating how you have integrated the investigated issues into the purpose, design, and/or execution of your project. Document your process and describe how your human practices work informed and shaped your project at different stages.
 
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<h3>Best Integrated Human Practices Special Prize</h3>
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<p>To compete for the Best Integrated Human Practices prize, please describe your work on this page and also fill out the description on the judging form. </p>
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<img src="https://static.igem.org/mediawiki/2019/6/64/T--DTU-Denmark--safetysvg2.svg" class="safetysecondimg"/>
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<p>How does your project affect society and how does society influence the direction of your project? How might ethical considerations and stakeholder input guide your project purpose and design and the experiments you conduct in the lab? How does this feedback enter into the process of your work all through the iGEM competition? Document a thoughtful and creative approach to exploring these questions and how your project evolved in the process to compete for this award!</p>
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<p>You must also delete the message box on the top of this page to be eligible for this prize.</p>
 
  
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<p style="color:#000; font-size:14px;"><br><br>
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(1) <a target="_blank" href="https://www.lgcstandards-atcc.org/products/all/1015.aspx">ATCC, <i>Aspergillus niger</i> van Tieghem (ATCC® 1015™) product information, accessed 7 September 2019 <https://www.lgcstandards-atcc.org/products/all/1015.aspx?><br>
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project description</a></p>
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                    <h5>Useful links</h5>
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<a href="https://2019.igem.org/Team:DTU-Denmark">Home</a>
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<a href="https://2019.igem.org/Team:DTU-Denmark/Description">Project description</a>
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                      <a href="https://2019.igem.org/Team:DTU-Denmark/Model">Modelling</a>
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<a href="https://2019.igem.org/Team:DTU-Denmark/Parts">Parts overview</a>
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<a href="https://2019.igem.org/Team:DTU-Denmark/Notebook">Notebook</a>
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<a href="https://2019.igem.org/Team:DTU-Denmark/Team">Team</a>
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<a href="https://2019.igem.org/Team:DTU-Denmark/Safety">Safety</a>
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<a href="https://2019.igem.org/Team:DTU-Denmark/Human_Practices">Human practices</a>
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                    <h5>About us</h5>
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                        <li><a href="mailto:dtubiobuilders@gmail.com">dtubiobuilders@gmail.com</a></li>
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Revision as of 17:58, 21 September 2019

Safety

The creation of a library of promoters may not be very applicable in the everyday life of most people, but the library can certainly have a great impact on many people’s lives. In determining how our project is good for the world, we looked to the UN’s Sustainable Development Goals (SDGs).
We have identified 5 main goals that our project contributes to. We call these our primary SDGs. Following this, we have further 2 goals that are affected by our efforts in the primary goals.

Regarding the organism

As described in the product, filamentous fungi are important producers in the biotechnological industry and they form the base of our project. We have chosen to work with Aspergillus niger as it is an important production organism, and the tools required to genetically engineer it already exists. We have used the specific strain ATCC1015 [1]. This Aspergillus strain is classified as Biosafety Level 1, which indicates means that it is safe to use and handle in the lab. In addition to this designation, we have performed a safety check-in, as spore-forming fungi are not directly in the whitelist.

Fermentation safety

During our project, we will be using larger-scale fermentations to verify our promoters. This introduces new challenges in safely handling our organism and the larger equipment. To the first point, Aspergillus niger, and many other filamentous fungi, the production of spores is dependent on external conditions of the fermentation.



(1) ATCC, Aspergillus niger van Tieghem (ATCC® 1015™) product information, accessed 7 September 2019
project description