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Project
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"I’m like a bio-brick I can be used anywhere, but I work best in the iGEM environment." - Antonio Vela-Gartner
We have developed a glutamate biosensor. Glutamate is a major excitatory neurotransmitter in the brain. However, excessive concentrations of glutamate can cause serious deleterious effects, including limbic seizures, amnesia, and brain damage. Our aim is to produce a biosensor that can be used to monitor the secretion of glutamate by neurons grown from stem cells in vitro. This biosensor would consist of a bacterial cell line capable of fluorescing in response to extracellular glutamate.
![Relationship between Glutamate and Calcium](https://static.igem.org/mediawiki/2019/5/5e/T--Unimelb--glutamate_process.png)
![Wet lab Image](https://static.igem.org/mediawiki/2019/e/e1/T--Unimelb--design.png)
![Glutamate Process](https://static.igem.org/mediawiki/2019/6/65/T--Unimelb--experiment.jpg)
![Safety sign](https://static.igem.org/mediawiki/2019/c/c2/T--Unimelb--note.jpg)
![Lecture hall](https://static.igem.org/mediawiki/2019/1/12/T--Unimelb--contribution.jpg)
![Template](https://static.igem.org/mediawiki/2019/4/41/T--Unimelb--attributions.jpg)