Team:Edinburgh OG/Team

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Hi! We're Remedye, a team of nine MSc students from the University of Edinburgh. We are each working on a separate aspect of dye bioremediation as part of our project.

Team Members

Biosensors

Jakub Chromy	Mirren White	Victor Nicolaus
Jakub is using directed evolution to improve the XylR toluene sensor to detect toxic dye intermediates.	Mirren is creating a heavy metal-sensitive biosensor to produce laccase in response to dye effluent.	Nico is designing riboswitches which can directly detect dye.

Dye-degrading enzymes

Cathal O'Reilly	Nathan Wu	Dylan Wang
Cathal used in vivo directed evolution to improve laccase enzymes and working on immobilizing laccases in biochar.	Nathan used in vitro directed evolution to search for improved laccase enzymes.	Dylan used rational design and simulation to redesign laccase, peroxidase, and azo-reductase for improved function.

Enzyme Immobilisation

Ping Chang		Wendy Chen
Ping is working on immobilizing peroxidase enzymes to the inner cell membrane and creating 'ghost shells' using lysis proteins.		Wendy's project focuses on immobilising azoreductase to curli fibres using the SpyTag-Spycatcher system.

Synthetic Silk production

	Ivan Rodriguez Jaubert
	Ivan is focusing on producing spider silk in E. coli in a move towards a circular economy.