Difference between revisions of "Team:Vilnius-Lithuania/Parts"

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<h4 class="page-heading">Overview</h4>
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<p>Until this moment, bacterial optogenetic regulation was only possible at the transcriptional level. However, the existing optogenetic controllers, even with reasonable control, all the transcriptional regulators have an imperfect design.</p>
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<p>Vilnius-Lithuania iGEM 2019 team created a collection that consists of parts that allow three-level modular control with light in bacteria.</p>
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<p>Modular transcription regulators CarH and Q-Pas1 are chimeric proteins that open up a possibility for researchers to control bacteria function at the transcriptional level with green and near-infrared (NIR) light.  
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<p>Light-inducible regulation system for the plasmid copy number enables to maintain a low plasmid copy number at the growth stage and increase it for the production stage.</p>
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<p>Finally, the post-translational control system works by increasing the POI's degradation rate and thus allows new possibilities to control bacterial dynamics at the post-translational level with rapid kinetics.</p>
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<h4 class="page-heading">Basic Parts</h4>
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<table style="width:100%;text-align:center">
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  <tr>
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    <th style="width:25%">Part Name</th>
 +
    <th style="width:25%">Type</th>
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    <th style="width:50%">Short Description</th>
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  </tr>
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  <tr>
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    <td>Jill</td>
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    <td>Smith</td>
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    <td>50</td>
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  </tr>
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  <tr>
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    <td>Eve</td>
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    <td>Jackson</td>
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    <td>94</td>
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  </tr>
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</table>
 
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Revision as of 18:18, 20 October 2019

Parts

Overview

Until this moment, bacterial optogenetic regulation was only possible at the transcriptional level. However, the existing optogenetic controllers, even with reasonable control, all the transcriptional regulators have an imperfect design.

Vilnius-Lithuania iGEM 2019 team created a collection that consists of parts that allow three-level modular control with light in bacteria.

Modular transcription regulators CarH and Q-Pas1 are chimeric proteins that open up a possibility for researchers to control bacteria function at the transcriptional level with green and near-infrared (NIR) light.

Light-inducible regulation system for the plasmid copy number enables to maintain a low plasmid copy number at the growth stage and increase it for the production stage.

Finally, the post-translational control system works by increasing the POI's degradation rate and thus allows new possibilities to control bacterial dynamics at the post-translational level with rapid kinetics.

Basic Parts

Part Name Type Short Description
Jill Smith 50
Eve Jackson 94
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