Difference between revisions of "Team:Bulgaria"
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| − | + | </circle> | |
| − | + | </svg> | |
| − | + | </div> | |
| − | + | </div> | |
| − | + | <section class="intro intro-home"> | |
| − | + | <div class="logo-wrap"> | |
| − | + | <img src="https://2019.igem.org/wiki/images/f/f5/T--Bulgaria--logo.png" alt=""> | |
| − | + | </div> | |
| − | + | <div class="txt-wrap"> | |
| − | + | <h2>iGEM Bulgaria</h2> | |
| − | + | <p>presents</p> | |
| − | + | <h1 class="product-name">Peptidator P-800</h1> | |
| − | + | </div> | |
| − | + | </section> | |
| − | + | <div class="navigation-container"> | |
| − | + | <button class="navigation-mobile-toggle"> | |
| − | + | <span class="hamburger"></span> | |
| − | + | </button> | |
| − | + | <nav class="navigation" id="navigation"> | |
| − | + | <div class="navigation-inner"> | |
| − | + | <ul class="navigation-list"> | |
| − | + | <li class="link"> | |
| − | + | <a href="https://2019.igem.org/Team:Bulgaria">Home</a> | |
| − | + | </li> | |
| − | + | <li class="link has-children"> | |
| − | + | <a>Team</a> | |
| − | + | <ul class="nested-links"> | |
| − | + | <li> | |
| − | + | <a href="https://2019.igem.org/Team:Bulgaria/Team">Team Members</a> | |
| − | + | </li> | |
| − | + | <li> | |
| − | + | <a href="https://2019.igem.org/Team:Bulgaria/Collaborations">Collaborations</a> | |
| − | + | </li> | |
| − | + | <li> | |
| − | + | <a href="https://2019.igem.org/Team:Bulgaria/Attributions">Attributions</a> | |
| − | + | </li> | |
| − | + | </ul> | |
| − | + | </li> | |
| − | + | <li class="link has-children"> | |
| − | + | <a>Project</a> | |
| − | + | <ul class="nested-links"> | |
| − | + | <li> | |
| − | + | <a href="https://2019.igem.org/Team:Bulgaria/Description">Description & Inspiration</a> | |
| − | + | </li> | |
| − | + | <li> | |
| − | + | <a href="https://2019.igem.org/Team:Bulgaria/Design">Design</a> | |
| − | + | </li> | |
| − | + | <li> | |
| − | + | <a href="https://2019.igem.org/Team:Bulgaria/Labbook">Lab book</a> | |
| − | + | </li> | |
| + | <li> | ||
| + | <a href="https://2019.igem.org/Team:Bulgaria/Contribution">Contribution & Improvement</a> | ||
| + | </li> | ||
| + | <li> | ||
| + | <a href="https://2019.igem.org/Team:Bulgaria/Results">Results</a> | ||
| + | </li> | ||
| + | </ul> | ||
| + | </li> | ||
| + | <li class="link"> | ||
| + | <a href="https://2019.igem.org/Team:Bulgaria/Parts">Parts</a> | ||
| + | </li> | ||
| + | <li class="link"> | ||
| + | <a href="https://2019.igem.org/Team:Bulgaria/Safety">Safety</a> | ||
| + | </li> | ||
| + | <li class="link"> | ||
| + | <a href="https://2019.igem.org/Team:Bulgaria/Human_Practices">Human Practices</a> | ||
| + | </li> | ||
| + | <li class="link"> | ||
| + | <a href="https://igem.org/2019_Judging_Form?team=Bulgaria">Judging Form</a> | ||
| + | </li> | ||
| + | <li class="link"> | ||
| + | <a href="https://2019.igem.org/Team:Bulgaria/Achievements" class="img-wrapper" title="Achievements"> | ||
| + | <img src="https://image.flaticon.com/icons/png/512/49/49965.png" alt=""> | ||
| + | </a> | ||
| + | </li> | ||
| + | </ul> | ||
| + | </div> | ||
| + | </nav> | ||
| + | </div> | ||
| + | <main class="container home-page"> | ||
| + | <div class="item-container"> | ||
| + | <svg class="home-curve" xmlns="http://www.w3.org/2000/svg" viewBox="-1 0 102 800" preserveAspectRatio="none"> | ||
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| + | <div class="item"> | ||
| + | <div class="content"> | ||
| + | <p>Antibiotic resistance is one of the most urgent threats to public health.</p> | ||
| + | </div> | ||
| + | <div class="img-wrap" style="background-image: url('https://2019.igem.org/wiki/images/6/62/T--Bulgaria--home-circle-01.gif');"> | ||
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| + | <div class="item"> | ||
| + | <div class="content medium"> | ||
| + | <p>If no action is taken, multiresistant bacteria could cause 10 million deaths each year by 2050 according to the UN Interagency Coordination Group (IACG) on Antimicrobial Resistance.</p> | ||
| + | </div> | ||
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</div> | </div> | ||
| − | <div class=" | + | <div class="item"> |
| − | < | + | <div class="content medium"> |
| − | < | + | <p>One of the most promising candidates for battling pathogens is natural organic compounds, like antimicrobial peptides. </p> |
| − | </ | + | </div> |
| − | < | + | <div class="img-wrap" style="background-image: url('https://2019.igem.org/wiki/images/4/42/T--Bulgaria--home-circle-03.gif');"> |
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</div> | </div> | ||
| − | <div class=" | + | <div class="item"> |
| − | <a href="https:// | + | <div class="content medium"> |
| − | + | <p>Our novel synthetic platform for high throughput isolation and characterization of peptides with antimicrobial properties serves as The Terminator for multi-resistant bacterial pathogens.</p> | |
| − | + | </div> | |
| − | + | <div class="img-wrap" style="background-image: url('https://2019.igem.org/wiki/images/1/19/T--Bulgaria--home-circle-04.jpg');"> | |
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| − | + | </div> | |
| − | + | </div> | |
| − | + | <div class="item"> | |
| − | + | <div class="content small"> | |
| − | + | <p>We used the available genomic sequencing data as a source of novel peptide sequences that can be used instead of antibiotics. To identify such elements, we used different versions of the BLAST algorithm and known antimicrobial peptides as quarries. Our sequences are isolated from Carcharodon carcharias or great white shark.</p> | |
| − | + | </div> | |
| − | + | <div class="img-wrap clean"> | |
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| − | + | <div class="item"> | |
| − | + | <div class="content medium"> | |
| − | + | <p>The next step would be to have these exact sequences synthesized as an oligonucleotide pool and cloned like an expression library in E.coli. </p> | |
| − | + | </div> | |
| − | + | <div class="img-wrap" style="background-image: url('https://2019.igem.org/wiki/images/c/c8/T--Bulgaria--home-circle-06.jpg');"> | |
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| − | + | <p>Last but not least, the activity of this library is tested against a selected group of indicator strains that represent most of the major important human and animal pathogens as to find the perfect Peptidator.</p> | |
| − | + | </div> | |
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Latest revision as of 23:50, 21 October 2019
iGEM Bulgaria
presents
Peptidator P-800
Antibiotic resistance is one of the most urgent threats to public health.
If no action is taken, multiresistant bacteria could cause 10 million deaths each year by 2050 according to the UN Interagency Coordination Group (IACG) on Antimicrobial Resistance.
One of the most promising candidates for battling pathogens is natural organic compounds, like antimicrobial peptides.
Our novel synthetic platform for high throughput isolation and characterization of peptides with antimicrobial properties serves as The Terminator for multi-resistant bacterial pathogens.
We used the available genomic sequencing data as a source of novel peptide sequences that can be used instead of antibiotics. To identify such elements, we used different versions of the BLAST algorithm and known antimicrobial peptides as quarries. Our sequences are isolated from Carcharodon carcharias or great white shark.
The next step would be to have these exact sequences synthesized as an oligonucleotide pool and cloned like an expression library in E.coli.
Last but not least, the activity of this library is tested against a selected group of indicator strains that represent most of the major important human and animal pathogens as to find the perfect Peptidator.