Team:DUT China B

Document

BALDR: A light driven

We want to achieve red light navigated movement in Chlamydomonas Reinhardtii, making it easier to function as cell micro-robots. With about 10 um size and strong motion ability, C.Reinhartii is the ideal chassis organism for operation.

Applications and Bottlenecks of Cell-based Micro-robots

Micro-organisms has been developed as micro-robots in drug delivery, genetic and cellular therapeutics. Compared with mechanical robots, cell-based micro-robots have a more complete controlling system and a better energy conversion system. However, how to achieve precise control over them remains a great challenge to researchers. C.Reinhardtii, with its stronger motility and inborn light sensing system, has become a desired choice to make cell-based micro-robots.

The Design of Molecular Light Converter

We combined optically polymeric protein with split Ranilla luciferase, realizing the recovery of complete luciferase and the activation of blue light under the control of infrared light. This molecular light converter will produce blue light inside C.Reinhardtii and thus activate the algae.(Check out our Design)