Line 15: | Line 15: | ||
cursor: pointer !important; | cursor: pointer !important; | ||
} | } | ||
− | |||
.about-contentbox1 { | .about-contentbox1 { | ||
margin-top: 80px; | margin-top: 80px; | ||
Line 54: | Line 53: | ||
.img-float-right{ | .img-float-right{ | ||
float:right; | float:right; | ||
+ | vspace: 10px; | ||
+ | hspace:10px; | ||
} | } | ||
.img-float-left{ | .img-float-left{ | ||
float: left; | float: left; | ||
+ | vspace: 10px; | ||
+ | hspace:10px; | ||
} | } | ||
</style> | </style> | ||
Line 70: | Line 73: | ||
<div class="about-contentbox1"> | <div class="about-contentbox1"> | ||
<div> | <div> | ||
− | + | <h2>Demonstrate</h2> | |
− | <h2> | + | <p>In this page, we provide simulation results along with experiment results. Simulations are based on a Mathematica numerical simulation package CRNsimulator [1]. Unitless concentrations and rate constants are utilized to simplify the model. For more details, please refer to our <a href="https://2019.igem.org/Team:SEU/Model">Model Page.</a></p> |
− | + | ||
− | <p>In this | + | |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | < | + | <h3>Dry Experiments</h3> |
− | + | <p>1.The simulation results of each calculation operation. </p> | |
− | < | + | <p><b>Addition:</b></p> |
− | < | + | <p>The figure below shows the numerical simulation result of a set of reactions:\(A_1 \xrightarrow{k} O,\quad A_2 \xrightarrow{k_2} O, \quad A_3 \xrightarrow{k_3} O\) which perform addition calculation. The initial concentrations (input values) are 1, 2 and 3, respectively (dashed lines in the figure). The output result is the sum of such values (solid red line in the figure).</p> |
− | <p> | + | <center> |
− | < | + | <img src="https://static.igem.org/mediawiki/2019/8/84/T--SEU--additionSim.png" width="310" height="138" > </center> |
− | < | + | <p><b>Subtraction:</b></p> |
− | + | <p>The figure below shows the reaction \(A+B \xrightarrow{k} \phi\) which is a subtractor. There are two tests shown in this figure: \([A_1](0)=3, [B_1](0)=2\) and \([A_2](0)=2, [B_2](0)=4\). </p> | |
− | <p> | + | <center> |
− | + | <img src="https://static.igem.org/mediawiki/2019/9/93/T--SEU--subtractionSim.png" width="310" height="141" ></center> | |
− | + | <p><b>Multiplication:</b></p> | |
− | + | <p>The numerical results of reactions \(\alpha \xrightarrow{k_1} \phi, A+B+\alpha \xrightarrow{k_2} A+B+\alpha+C\) are shown in the figure below. Initial concentrations are \([A](0)=4, [B](0)=3\). The result shows that the final concentration of \(C\) reaches \(4 \times 3=12\).</p> | |
− | <p>The | + | <center> |
− | + | <img src="https://static.igem.org/mediawiki/2019/b/bb/T--SEU--multiplicationSim.png" width="310" height="154" ></center> | |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | < | + | |
− | < | + | |
− | + | ||
− | <p> | + | |
− | + | ||
− | <p> | + | |
− | + | ||
− | + | ||
− | < | + | |
− | + | ||
+ | <p>2.We use such a model to construct a chemical neuron.</p> | ||
+ | <p>A pattern recognition example in computer simulation is shown here. The DNA-based neuron is trained to recognize a 'T' in a \(3 \times 3\) grid. | ||
+ | |||
+ | Only after 10 times of training, the neuron can successfully recognize the target 'T'.</p> | ||
+ | <center><img src="https://static.igem.org/mediawiki/2019/5/5c/T--SEU--pattern.png" width="620" height="691" ></center> | ||
+ | |||
+ | <h3>Wet Experiment</h3> | ||
+ | <p>3.The DNA experment results of our calculation operations.</p> | ||
+ | |||
+ | <h3>References</h3> | ||
+ | <p>[1] <a href="http://users.ece.utexas.edu/~soloveichik/crnsimulator.html">CRNsimulator.</a></p> | ||
− | |||
</div> | </div> | ||
</div> | </div> |
Revision as of 08:28, 5 October 2019
![](https://static.igem.org/mediawiki/2019/b/be/T--SEU--tm-wy1.jpg)
Demonstrate
In this page, we provide simulation results along with experiment results. Simulations are based on a Mathematica numerical simulation package CRNsimulator [1]. Unitless concentrations and rate constants are utilized to simplify the model. For more details, please refer to our Model Page.
Dry Experiments
1.The simulation results of each calculation operation.
Addition:
The figure below shows the numerical simulation result of a set of reactions:\(A_1 \xrightarrow{k} O,\quad A_2 \xrightarrow{k_2} O, \quad A_3 \xrightarrow{k_3} O\) which perform addition calculation. The initial concentrations (input values) are 1, 2 and 3, respectively (dashed lines in the figure). The output result is the sum of such values (solid red line in the figure).
![](https://static.igem.org/mediawiki/2019/8/84/T--SEU--additionSim.png)
Subtraction:
The figure below shows the reaction \(A+B \xrightarrow{k} \phi\) which is a subtractor. There are two tests shown in this figure: \([A_1](0)=3, [B_1](0)=2\) and \([A_2](0)=2, [B_2](0)=4\).
![](https://static.igem.org/mediawiki/2019/9/93/T--SEU--subtractionSim.png)
Multiplication:
The numerical results of reactions \(\alpha \xrightarrow{k_1} \phi, A+B+\alpha \xrightarrow{k_2} A+B+\alpha+C\) are shown in the figure below. Initial concentrations are \([A](0)=4, [B](0)=3\). The result shows that the final concentration of \(C\) reaches \(4 \times 3=12\).
![](https://static.igem.org/mediawiki/2019/b/bb/T--SEU--multiplicationSim.png)
2.We use such a model to construct a chemical neuron.
A pattern recognition example in computer simulation is shown here. The DNA-based neuron is trained to recognize a 'T' in a \(3 \times 3\) grid. Only after 10 times of training, the neuron can successfully recognize the target 'T'.
![](https://static.igem.org/mediawiki/2019/5/5c/T--SEU--pattern.png)
Wet Experiment
3.The DNA experment results of our calculation operations.
References
[1] CRNsimulator.