Difference between revisions of "Team:Cornell/Entrepreneurship"

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{{Cornell}}
 
 
<html>
 
<html>
 +
<head>
 +
    <style>
 +
        /* hides "Team:Cornell" and iGEM logo */
 +
        #top_title {
 +
            display: none;
 +
        }
  
 +
        /* removes padding below footer */
 +
        #globalWrapper {
 +
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 +
        #content {
 +
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            width: 100% !important;
 +
            margin-top: 0px;
 +
            margin-left: 0px ;
 +
        }
  
−
<div class="clear"></div>
+
        /* removes default styling for home banner tagline */
 +
        #HQ_page p {
 +
            font-family: 'Opens Sans', sans-serif;
 +
        }
  
 +
        /* removes small extra margin at very bottom below footer */
 +
        p {
 +
            margin: 0;
 +
        }
  
 +
        /* removes bullets from Toolkit dropdown menu */
 +
        ul {
 +
            list-style-image: none;
 +
        }
  
−
<div class="column full_size">
+
  /********************************* PRACTICES TIMELINE  ********************************/
  
−
<h1>Entrepreneurship</h1>
+
  .timeline {
 +
      position: relative;
 +
      margin-top: 100px;
 +
  }
  
−
</div>
+
  .timeline::before {
 +
      content: '';
 +
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      margin: 0;
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 +
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 +
      width: 1.5px;
 +
      background: #808080;
 +
      z-index: 1;
 +
  }
  
−
<div class="column two_thirds_size">
+
  .inspiration-timeline::before {
−
<h3>Best Supporting Entrepreneurship Special Prize</h3>
+
      transform: translate(-50%, -52%);
 +
      height: 1250px;
 +
      top: 650px;
 +
  }
  
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<p>The Best Supporting Entrepreneurship award recognizes exceptional effort to build a business case and commercialize an iGEM project. This award is open to all teams to show that entrepreneurship is something all teams can aspire to do with their project. This award can go to an new project, or to a previous project that a team aimed to commercialize. Have you filed a provisional patent on your project/device/process? Have you raised money to build and ship products? Have you pitched your idea to investors and received money? As always in iGEM, the aim is to impress the judges!
+
  .ideation-timeline::before {
 +
      transform: translate(-50%, -51%);
 +
      height: 2370px;
 +
      top: 1215px;
 +
  }
  
−
<br><br>
+
  .implementation-timeline::before {
−
To compete for the <a href="https://2019.igem.org/Judging/Awards">Best Supporting Entrepreneurship prize</a>, please describe your work on this page and also fill out the description on the <a href="https://2019.igem.org/Judging/Judging_Form">judging form</a>.
+
      transform: translate(-50%, -51.2%);
−
<br><br>
+
      height: 1140px;
−
You must also delete the message box on the top of this page to be eligible for this prize.
+
      top: 580px;
−
</p>
+
  }
−
</p>
+
−
</div>
+
  
−
<div class="column third_size">
+
  .timeline-block {
−
<div class="highlight decoration_A_full">
+
      margin-bottom: 50px;
−
<h3>Inspiration</h3>
+
  }
−
<p>You can look at what other teams did to get some inspiration! <br />
+
−
Here are a few examples:</p>
+
−
<ul>
+
−
<li><a href="https://2016.igem.org/Team:Sydney_Australia">2016 Sydney Australia</a></li>
+
−
<li><a href="https://2016.igem.org/Team:Pasteur_Paris">2016 Pasteur Paris</a></li>
+
−
<li><a href="https://2014.igem.org/Team:UCC_Ireland">2014 UCC Ireland</a></li>
+
−
<li><a href="https://2014.igem.org/Team:Imperial">2014 Imperial College London</a></li>
+
−
</ul>
+
−
</div>
+
−
</div>
+
  
 +
  .timeline-img {
 +
      display: block;
 +
      margin: 0 auto;
 +
      padding-top: 25px;
 +
      width: 100%;
 +
  }
  
 +
  .date {
 +
      font-family: 'Source Sans Pro', serif;
 +
      font-size: 18px;
 +
  }
  
−
<div class="clear"></div>
+
  .timeline-content h3 {
 +
      font-family: 'Source Sans Pro', serif;
 +
      font-weight: bold;
 +
      font-size: 20px;
 +
  }
  
−
<div class="column full_size">
+
  .timeline-content p {
−
<h3>Patents and intellectual property</h3>
+
      line-height: 1.8;
 +
      font-size: 14px;
 +
  }
  
−
<p>
+
  .timeline-content-left {
−
If your team is seriously considering commercializing and looking into building a company after the competition, you may want to look at how you are going to protect your work and secure investment. Investors will usually require some form of intellectual protection, so you may want to investigate how to apply for a patent or provisional patent in your country and region before disclosing your project at iGEM. Remember that you can only be evaluated in iGEM based on what you share on your wiki and at the Jamboree, so any work you don't present can't count towards your project. </p>
+
      padding-left: 0;
 +
      text-align: right;
 +
  }
  
−
<p>This is an area where we are different as we care about sharing, openness and contributing to the community and investors don't always agree with these values. It is up to you and your team to decide what to do. Remember that most universities have a commercialization department and that you can talk to them before coming to a decision.  
+
  .timeline-content-right {
−
</p>
+
      padding-right: 0;
−
</div>
+
  }
  
−
<div class="clear"></div>
+
  .marker {
 +
      width: 16px;
 +
      height: 16px;
 +
      border-radius: 50%;
 +
      border: 2px solid #567151;
 +
      background: #567151;
 +
      margin: 0;
 +
      position: absolute;
 +
      left: 50%;
 +
      transform: translate(-50%, -50%);
 +
      z-index: 3;
 +
  }
  
 +
  .urban-info {
 +
      font-style: italic;
 +
      text-align: center;
 +
  }
  
 +
  @media (max-width: 995px) {
 +
      .timeline::before {
 +
          display: none;
 +
      }
 +
      .marker {
 +
          display: none;
 +
      }
 +
  }
 +
 +
 +
  /********************************* END PRACTICES TIMELINE  ********************************/
 +
 +
 +
  /* Typography */
 +
 +
  .text-left {
 +
      text-align: left;
 +
  }
 +
 +
  .text-right {
 +
      text-align: right;
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      text-align: center;
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  .text-justify {
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      text-align: justify;
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  }
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  .text-nowrap {
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  }
 +
 +
 +
  /* Tab */
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  .tab-section-01 .content>.tab-pane {
 +
      display: none;
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  .tab-section-01 .content>.active {
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  .tab-section-01 .tabs li {
 +
      display: inline-block;
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      border: 3px solid #a0e0bd;
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      font-weight: 700;
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      border-bottom-color: white;
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      border-top: 1px solid #30b397;
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  .tab-section-01.style-2 .tabs>li.active a,
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  .tab-section-01.style-2 .tabs>li.active a:hover,
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      cursor: default;
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      background-color: #ffffff;
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 +
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 +
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      display: block;
 +
      width: 100%;
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      height: 1px;
 +
      background-color: transparent;
 +
  }
 +
 +
  .tab-section-01.style-3 .tabs>li a {
 +
      padding: 10px 30px;
 +
  }
 +
 +
  .tab-section-01.style-3 .tabs>li a:hover {
 +
      background-color: #eeeeee;
 +
  }
 +
 +
  .tab-section-01.style-3 .tabs>li.active {
 +
      border-bottom-color: white;
 +
      border-top: 1px solid #30b397;
 +
  }
 +
 +
  .tab-section-01.style-3 .tabs>li.active:before {
 +
      content: '';
 +
      display: block;
 +
      width: 100%;
 +
      height: 1px;
 +
      background-color: #30b397;
 +
  }
 +
 +
  .tab-section-01.style-3 .tabs>li.active a,
 +
  .tab-section-01.style-3 .tabs>li.active a:hover,
 +
  .tab-section-01.style-3 .tabs>li.active a:focus {
 +
      cursor: default;
 +
      background-color: #ffffff;
 +
  }
 +
 +
  @media (max-width: 767px) {
 +
      .tab-section-01 .tabs li {
 +
          display: block;
 +
          margin-bottom: 20px;
 +
      }
 +
      .tab-section-01 .tabs li a {
 +
          width: 100%;
 +
          padding: 10px 35px;
 +
      }
 +
  }
 +
 +
 +
  /******************** GENERAL PAGES START ********************/
 +
 +
  @import url('https://fonts.googleapis.com/css?family=Merriweather|Open+Sans|Raleway');
 +
  html,
 +
  body {
 +
      width: 100%;
 +
      height: 100%;
 +
      margin: 0;
 +
      padding: 0;
 +
      overflow-x: hidden;
 +
  }
 +
 +
  body {
 +
      background-size: 40px 40px;
 +
  }
 +
 +
  p {
 +
      color: #000;
 +
      font-family: 'Open Sans', sans-serif;
 +
  }
 +
 +
  nav {
 +
      padding-top: 30px;
 +
      padding-bottom: 30px;
 +
      padding-right: 100px;
 +
      background-color: #a0e0bd;
 +
      height: 98px;
 +
  }
 +
 +
  .nav-bar-logo {
 +
      vertical-align: top;
 +
      display: inline-block;
 +
      float: left;
 +
      margin-left: 80px;
 +
      margin-top: -5px;
 +
  }
 +
 +
  .nav-bar-logo img {
 +
      width: 140px;
 +
  }
 +
 +
  .nav-bar-main-menu {
 +
      font-family: 'Raleway', sans-serif;
 +
  }
 +
 +
  .banner-container {
 +
      display: flex;
 +
      flex-direction: row;
 +
      flex-wrap: wrap;
 +
      justify-content: center;
 +
  }
 +
 +
  .home-banner-logo {
 +
      height: 250px;
 +
      width: 35%;
 +
      padding-top: 170px;
 +
      margin-right: -400px;
 +
  }
 +
 +
  .home-banner-wrapper {
 +
      background: #a0e0bd;
 +
      height: 400px;
 +
      width: 100%;
 +
  }
 +
 +
  .home-banner-plants {
 +
      height: 400px;
 +
      width: 80%;
 +
  }
 +
 +
  .dropbtn {
 +
      background-color: transparent;
 +
      text-decoration: none;
 +
      padding: 15px;
 +
      margin: 0px;
 +
      font-size: 15px;
 +
      border: none;
 +
      color: #fff;
 +
  }
 +
 +
  @media (max-width: 1050px) {
 +
      .dropbtn {
 +
          font-size: 12px;
 +
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 +
  }
 +
 +
  .dropdown {
 +
      position: relative;
 +
      vertical-align: top;
 +
      display: inline-block;
 +
      float: right;
 +
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 +
 +
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 +
      list-style-type: none;
 +
  }
 +
 +
  .dropdown a {
 +
      position: relative;
 +
      display: inline-block;
 +
      color: #e8b023;
 +
      text-decoration: none;
 +
  }
 +
 +
  .dropdown-content {
 +
      display: none;
 +
      position: absolute;
 +
      background-color: #016c64;
 +
      color: #ffffff;
 +
      width: 200px;
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      font-size: 14px;
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      box-shadow: 0px 8px 16px 0px rgba(0, 0, 0, 0.2);
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      z-index: 1;
 +
  }
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 +
  .toolkit-dropdown-content {
 +
      width: 720px;
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      left: -160px;
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  .modeling-dropdown-content {
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 +
  .human-dropdown-content {
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      left: 12px;
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 +
  .outreach-dropdown-content {
 +
      width: 230px;
 +
      left: -40px;
 +
  }
 +
 +
  .team-dropdown-content {
 +
      width: 140px;
 +
      left: -35px;
 +
  }
 +
 +
  .dropdown-content a {
 +
      color: #ffffff;
 +
      padding: 12px 16px;
 +
      text-decoration: none;
 +
      display: block;
 +
  }
 +
 +
  .wet-lab-list-title,
 +
  .doc-list-title,
 +
  .pd-list-title {
 +
      padding-top: 12px;
 +
      padding-left: 16px;
 +
      padding-bottom: 14px;
 +
  }
 +
 +
  .nav-second-col {
 +
      margin-left: 30px;
 +
  }
 +
 +
  .nav-third-col {
 +
      margin-left: 30px;
 +
  }
 +
 +
  .dropbtn:hover,
 +
  .active-page {
 +
      color: #016c64;
 +
      transition-duration: 0.5s;
 +
  }
 +
 +
  .dropdown-content a:hover {
 +
      color: #016c64;
 +
      background-color: #ffffff;
 +
  }
 +
 +
  .dropdown:hover .dropdown-content {
 +
      display: block;
 +
  }
 +
 +
  footer {
 +
      padding: 35px;
 +
      position: relative;
 +
      text-align: center;
 +
      background-color: #a0e0bd;
 +
  }
 +
 +
  .footer-wrapper {
 +
      margin: auto;
 +
      display: inline-block;
 +
  }
 +
 +
  .icon-wrapper {
 +
      display: inline-block;
 +
      position: relative;
 +
      padding-right: 18px;
 +
      border-right: 0.5px solid white;
 +
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 +
 +
  .icon-wrapper-last {
 +
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 +
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 +
 +
  .icon {
 +
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 +
  }
 +
 +
  .icon img {
 +
      height: 24px;
 +
  }
 +
 +
 +
  /******************** GENERAL PAGES END ********************/
 +
 +
 +
  /******************** Entrepreneurship PAGE START ********************/
 +
 +
  .content-title {
 +
      font-family: 'Merriweather', serif;
 +
      font-size: 30px;
 +
      font-weight: 700;
 +
      color: #000;
 +
      position: relative;
 +
      margin-bottom: 40px;
 +
      text-align: center;
 +
  }
 +
 +
  .text-justify {
 +
      color: #000;
 +
      font-family: 'Open Sans', sans-serif;
 +
      font-size: 16px;
 +
      padding-bottom: 60px;
 +
  }
 +
 +
  .timeline-block .text-justify {
 +
      color: #949494;
 +
      font-size: 14px;
 +
  }
 +
 +
  .references {
 +
      color: #949494;
 +
      margin-bottom: 60px;
 +
  }
 +
 +
  .timeline-button-wrapper {
 +
      text-align: center;
 +
  }
 +
 +
  .entrepreneurship-page-banner {
 +
      background-color: #a0e0bd;
 +
      font-size: 10px;
 +
  }
 +
 +
  .entrepreneurship-page-content-wrapper {
 +
      padding: 80px 80px 0px 80px;
 +
  }
 +
 +
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  /******************** Entrepreneurship PAGE END ********************/
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 +
      grid-area: navbar;
 +
  }
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  .nav-bar-main-menu .dropdown:nth-child(5) .dropdown-contentx {
 +
      display: grid;
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 +
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      grid-area: navbar;
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      display: grid;
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      grid-template-columns: auto;
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      grid-template-areas: 'navbar' 'entrepreneurshippagebanner' 'pandppagecontent' 'footer';
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      grid-area: entrepreneurshippagebanner;
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  /******************** Entrepreneurship PAGE GRID END ********************/
 +
 +
    </style>
 +
    <title>Team:Cornell - 2019.igem.org</title>
 +
    <!--CSS-->
 +
    <link rel="stylesheet" href="styles/bootstrap.min.css">
 +
    <link rel="stylesheet" href="styles/business.css">
 +
    <!-- JS-->
 +
    <script src="js/jquery-1.11.2.min.js" type="text/javascript"></script>
 +
</head>
 +
 +
<body>
 +
    <div class = "entrepreneurship-page-wrapper">
 +
        <!------------------------ NAV BAR START ------------------------>
 +
        <nav>
 +
            <div class="nav-bar-wrapper">
 +
                <div class="nav-bar-logo">
 +
                        <a href="https://2019.igem.org/Team:Cornell"><img src="images/logo.png" alt="reHAB"></a>
 +
                </div>
 +
                <div class="nav-bar-main-menu">
 +
                    <div class="dropdown">
 +
                        <button class="dropbtn">TEAM</button>
 +
                        <div class="dropdown-content team-dropdown-content">
 +
                            <a href="https://2019.igem.org/Team:Cornell/Team">BIOS</a>
 +
                            <a href="https://2019.igem.org/Team:Cornell/Sponsors">SPONSORS</a>
 +
                            <a href="https://2019.igem.org/Team:Cornell/Attributions">ATTRIBUTIONS</a>
 +
                        </div>
 +
                    </div>
 +
                    <div class="dropdown">
 +
                        <button class="dropbtn">OUTREACH</button>
 +
                        <div class="dropdown-content outreach-dropdown-content">
 +
                            <a href="https://2019.igem.org/Team:Cornell/EducationAndEngagement">EDUCATION & ENGAGEMENT</a>
 +
                            <a href="https://2019.igem.org/Team:Cornell/Collaborations">COLLABORATIONS</a>
 +
                        </div>
 +
                    </div>
 +
                    <div class="dropdown">
 +
                        <button class="dropbtn active-page">HUMAN PRACTICES</button>
 +
                        <div class="dropdown-content human-dropdown-content">
 +
                            <a href="https://2019.igem.org/Team:Cornell/IntegratedPractices">INTEGRATED PRACTICES</a>
 +
                            <a href="https://2019.igem.org/Team:Cornell/Policies">POLICIES</a>
 +
                            <a href="https://2019.igem.org/Team:Cornell/Entrepreneurship">ENTREPRENEURSHIP</a>
 +
                        </div>
 +
                    </div>
 +
                    <div class="dropdown">
 +
                        <button class="dropbtn"
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                            onclick="location.href='https://2019.igem.org/Team:Cornell/Model'">MODELING</button>
 +
                    </div>
 +
                    <div class="dropdown">
 +
                        <button class="dropbtn">TOOLKIT</button>
 +
                        <div class="dropdown-content toolkit-dropdown-content">
 +
                            <ul>
 +
                                <div class="nav-first-col">
 +
                                    <li class="wet-lab-list-title"><b>WET LAB</b></li>
 +
                                    <li><a href="https://2019.igem.org/Team:Cornell/Foundations">FOUNDATIONS</a></li>
 +
                                    <li><a href="https://2019.igem.org/Team:Cornell/Demonstrate">DEMONSTRATE</a></li>
 +
                                    <li><a href="https://2019.igem.org/Team:Cornell/Parts">PARTS</a></li>
 +
                                    <li><a href="https://2019.igem.org/Team:Cornell/BasicParts">BASIC PARTS</a></li>
 +
                                    <li><a href="https://2019.igem.org/Team:Cornell/CompositeParts">COMPOSITE PARTS</a></li>
 +
                                </div>
 +
                                <div class="nav-second-col">
 +
                                    <li class="pd-list-title"><b>DESIGN</b></li>
 +
                                    <li><a href="https://2019.igem.org/Team:Cornell/DesignProcess">DESIGN PROCESS</a></li>
 +
                                </div>
 +
                                <div class="nav-third-col">
 +
                                    <li class="doc-list-title"><b>DOCUMENTATION</b></li>
 +
                                    <li><a href="https://2019.igem.org/Team:Cornell/Notebook">NOTEBOOK</a></li>
 +
                                    <li><a href="https://2019.igem.org/Team:Cornell/Safety">SAFETY</a></li>
 +
                                </div>
 +
                            </ul>
 +
                        </div>
 +
                    </div>
 +
                    <div class="dropdown">
 +
                        <button class="dropbtn"
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                            onclick="location.href='https://2019.igem.org/Team:Cornell/Description'">ABOUT</button>
 +
                    </div>
 +
                    <div class="dropdown">
 +
                        <button class="dropbtn"
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                            onclick="location.href='https://2019.igem.org/Team:Cornell'">HOME</button>
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                    </div>
 +
                </div>
 +
            </div>
 +
        </nav>
 +
        <!------------------------ NAV BAR END ------------------------>
 +
        <!------------------------ STANDARD PAGE BANNER START ------------------------>
 +
        <header class="entrepreneurship-page-banner">
 +
            <svg viewBox="0 0 100 100" width=100% height=100%>
 +
                <circle cx="50" cy="50" r="40" fill="white" fill-opacity="0.4"/>
 +
                <text text-anchor="middle" alignment-baseline="middle" x=50% y=50%>Entrepreneurship</text>
 +
            </svg>
 +
        </header>
 +
        <!------------------------ STANDARD PAGE BANNER END ------------------------>
 +
        <!------------------------PRACTICES CONTENT------------------------>
 +
        <!------------------------OVERVIEW------------------------>
 +
        <div class = "entrepreneurship-page-content-wrapper">
 +
            <section class="entrepreneurship-page-content">
 +
                <div>
 +
                    <div class="content-title">OVERVIEW</div>
 +
                    <div class="text-justify">
 +
                    Harmful algae blooms (HABs) have emerged as one of our most pressing environmental crises. These blooms destroy marine and freshwater ecosystems by removing oxygen from the water as it decomposes, starving marine life. When blooms get especially dense, they block sunlight from reaching the depths of the lake, creating dead zones. They produce toxins dangerous enough to poison animals, and can cause illnesses in humans. <br><br>
 +
                    In our very own Cayuga Lake, HABs have severely affected the quality of the ecosystem. Thus it becomes a personal interest to do what we can to tackle this issue. We developed a novel solution to detect and degrade toxic microcystin-LR (MC-LR) byproducts from HABs. Microcystins have been shown to poison and kill animals, and have caused harm to humans through irritation of the throat and lungs, and long-term kidney and liver damage. <br><br>
 +
                    The purpose of our project is to detect and degrade MC-LR. Our solution is reHAB, an aptamer based colorimetric detection sensor to detect microcystins. To get samples for testing, we designed a boat to eliminate the need for humans to manually collect water samples and record bloom sites. This detection ability is combined with a degradation functionality. We introduced multiple enzymes that have been shown to effectively degrade MC-LR into the bacteria we use to degrade microcystins, and attached a tag from the TAT pathway to increase the efficiency of this degradation reaction. We house this within a bioreactor filled with alginate-beads that allows us to remediate large quantities of water at once.<br><br>
 +
                    </div>
 +
                </div>
 +
            </section>
 +
            <!------------------------END OVERVIEW------------------------>
 +
            <!------------------------DESCRIPTION------------------------>
 +
            <section class="entrepreneurship-page-content">
 +
                <div class="tab-section-01 style-1">
 +
                    <ul class="tabs timeline-button-wrapper">
 +
                        <li><a href="#tab0tab-1">BUSINESS CANVAS MODEL</a></li>
 +
                        <li><a href="#tab1tab-1">MARKET ANALYSIS</a></li>
 +
                        <li><a href="#tab2tab-1">FUTURE DEVELOPMENT</a></li>
 +
                       
 +
                    </ul>
 +
                    <hr>
 +
                    <div class="content timeline-content-wrapper bus-content" >
 +
                        <div id="tab0tab-1">
 +
                            <div class="tab-content">
 +
                                <div class="content-title">BUSINESS CANVAS MODEL</div>
 +
                                <div class="content">
 +
                                    <img alt="business canvas model" src="https://static.igem.org/mediawiki/2019/b/b9/T--Cornell--BusinessTemplate.png" width=100% height=auto><br>                           
 +
                                </div>
 +
                            </div> 
 +
                        </div>
 +
                        <hr>
 +
                        <div id="tab1tab-1">
 +
                            <div class="tab-content">
 +
                                <div class="content-title">MARKET ANALYSIS</div>
 +
                                <div class="text-justify">
 +
                                    The market for harmful algae bloom (HAB) cleanup is still developing. Control of HABs is currently focused around prevention, detection, and monitoring. Our project tackles a new area of the market: rehabilitation. Our product reHAB is able to detect and degrade one of the toxic chemicals that HABs produce, microcystin-LR (MC-LR). <br><br>
 +
Our main competitor for HAB detection is a comprehensive technique called ELISA. However, this method is slow and costly: despite being considered considered one of the fastest tests, ELISA still takes a full day to yield results. Algae blooms typically only last 3-5 days, but the remnants of toxin in harmful blooms persist-- reHAB’s quicker turnaround and ability to degrade microcystins proves it is the better alternative to ELISA. Thus far, little effort has been devoted towards actual remediation. Current treatment efforts have been centered around drinking water, or controlling and preventing HABs. reHAB is one of the first to step foot into the market for targeted HAB remediation.<br><br>
 +
Our project provides a quick and effective solution, targeting a new dimension of a multibillion dollar problem. HAB related economic losses in the United States was estimated to be $2.2 to $4.6 billion. The fishing industry has been particularly affected. reHAB can help minimize these losses by detecting and remediating our waters. It is novel solution to a pressing problem. <br><br>                     
 +
                                </div>
 +
                            </div> 
 +
                            <div class="content-title">SWOT ANALYSIS</div>
 +
                            <div class = "row match-my-cols">
 +
                                <div class = "col-md-6" style ='background-color: #e0ffdd;'>
 +
                                    <h4>Strengths</h4>
 +
                                    <ul class="bus-list">
 +
                                        <li>Reliable: consistently fast results and successful degradation</li>
 +
                                        <li>Cost Efficient: Easily scalable and low-cost production</li>
 +
                                        <li>Expertise: Strong understanding of the issue, thanks to our nearness to Cayuga Lake</li>
 +
                                        <li>Doing Good: Wide-scale benefits to both animals and humans</li>
 +
                                    </ul>
 +
                                </div>
 +
                                <div class = "col-md-6" style ='background-color: #ffdddd; padding-bottom: 60px;'>
 +
                                    <h4>Weaknesses</h4>
 +
                                    <ul class="bus-list">
 +
                                        <li>Big duties: A comparatively small boat must tackle larger blooms</li>
 +
                                        <li>Growing pains: Must establish product reliability and reputation amongst clients</li>
 +
                                    </ul>
 +
                                </div>
 +
                            </div>
 +
                            <div class = "row match-my-cols">
 +
                                <div class = "col-md-6" style ='background-color: #e0ffdd;'>
 +
                                    <h4>Opportunities</h4>
 +
                                    <ul class="bus-list">
 +
                                        <li>Increasing awareness of HABs and growing desire to solve this issue</li>
 +
                                        <li>No products on the market that both detect HABs and degrade microcystins </li>
 +
                                        <li>Revolutionizing current detection methods (inefficient direct water-testing)</li>   
 +
                                    </ul>
 +
                                </div>
 +
                                <div class = "col-md-6" style ='background-color: #ffdddd; padding-bottom: 20px;'>
 +
                                    <h4>Threats</h4>
 +
                                    <ul class="bus-list">
 +
                                        <li>Public’s negative perception of synthetic biology</li>
 +
                                        <li>Legal access to bodies of water with HABs, whether public or private, and gaining permissions to implement reHAB there</li>
 +
                                        <li>FDA/Government Regulations</li>
 +
                                    </ul>
 +
                                </div>
 +
                                </div>
 +
                        </div>
 +
                        <hr>
 +
                        <div id="tab2tab-1">
 +
                            <div class="tab-content">
 +
                                <div class="content-title">FUTURE DEVELOPMENT</div>
 +
                                <div class="text-justify">
 +
                                    The most valuable aspect of any product lies in its intellectual property. Given that our project exists on the forefront of aptamer-based detection technology, we would aim to patent the novel components of our project through the Cornell Center for Technology Licensing (CTL). Of particular focus would be our detection system, the most unique dimension of our product. <br><br>
 +
                                    The ingenuity and relevance of our project characterizes it as a necessary step in the right direction for harmful algal bloom mitigation. Our goal is to integrate our aptamer detection mechanism into large-scale systems in a way that other monitoring strategies have been unable to accomplish. According to the World Health Organization, there is an urgent need for the development of an animal friendly, rapid and cost-effective toxin analysis methodology for the future of microcystin detection. Our project has the potential to do just that. <br><br>
 +
                                    In order to accomplish this, we plan to accomplish the following: <br>
 +
                                    <ul class="bus-list">
 +
                                        <li>Further developing the aptamer-based detection system </li>
 +
                                        <li>Improving the automation of the boat system</li>
 +
                                        <li>Conducting market research to compile into case studies </li>
 +
                                        <li>Attaining resources for manufacturing and large-scale production</li>
 +
                                        <li>Reaching out to potential investors and buyers as well as affected community members</li>
 +
                                    </ul>                     
 +
                                </div>
 +
                            </div> 
 +
                        </div>       
 +
                    </div>
 +
                </div>
 +
            </section>
 +
        </div>
 +
        <!------------------------END DESCRIPTION------------------------>
 +
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Revision as of 03:22, 18 October 2019

Team:Cornell - 2019.igem.org

Entrepreneurship
OVERVIEW
Harmful algae blooms (HABs) have emerged as one of our most pressing environmental crises. These blooms destroy marine and freshwater ecosystems by removing oxygen from the water as it decomposes, starving marine life. When blooms get especially dense, they block sunlight from reaching the depths of the lake, creating dead zones. They produce toxins dangerous enough to poison animals, and can cause illnesses in humans.

In our very own Cayuga Lake, HABs have severely affected the quality of the ecosystem. Thus it becomes a personal interest to do what we can to tackle this issue. We developed a novel solution to detect and degrade toxic microcystin-LR (MC-LR) byproducts from HABs. Microcystins have been shown to poison and kill animals, and have caused harm to humans through irritation of the throat and lungs, and long-term kidney and liver damage.

The purpose of our project is to detect and degrade MC-LR. Our solution is reHAB, an aptamer based colorimetric detection sensor to detect microcystins. To get samples for testing, we designed a boat to eliminate the need for humans to manually collect water samples and record bloom sites. This detection ability is combined with a degradation functionality. We introduced multiple enzymes that have been shown to effectively degrade MC-LR into the bacteria we use to degrade microcystins, and attached a tag from the TAT pathway to increase the efficiency of this degradation reaction. We house this within a bioreactor filled with alginate-beads that allows us to remediate large quantities of water at once.

BUSINESS CANVAS MODEL
business canvas model
MARKET ANALYSIS
The market for harmful algae bloom (HAB) cleanup is still developing. Control of HABs is currently focused around prevention, detection, and monitoring. Our project tackles a new area of the market: rehabilitation. Our product reHAB is able to detect and degrade one of the toxic chemicals that HABs produce, microcystin-LR (MC-LR).

Our main competitor for HAB detection is a comprehensive technique called ELISA. However, this method is slow and costly: despite being considered considered one of the fastest tests, ELISA still takes a full day to yield results. Algae blooms typically only last 3-5 days, but the remnants of toxin in harmful blooms persist-- reHAB’s quicker turnaround and ability to degrade microcystins proves it is the better alternative to ELISA. Thus far, little effort has been devoted towards actual remediation. Current treatment efforts have been centered around drinking water, or controlling and preventing HABs. reHAB is one of the first to step foot into the market for targeted HAB remediation.

Our project provides a quick and effective solution, targeting a new dimension of a multibillion dollar problem. HAB related economic losses in the United States was estimated to be $2.2 to $4.6 billion. The fishing industry has been particularly affected. reHAB can help minimize these losses by detecting and remediating our waters. It is novel solution to a pressing problem.

SWOT ANALYSIS

Strengths

  • Reliable: consistently fast results and successful degradation
  • Cost Efficient: Easily scalable and low-cost production
  • Expertise: Strong understanding of the issue, thanks to our nearness to Cayuga Lake
  • Doing Good: Wide-scale benefits to both animals and humans

Weaknesses

  • Big duties: A comparatively small boat must tackle larger blooms
  • Growing pains: Must establish product reliability and reputation amongst clients

Opportunities

  • Increasing awareness of HABs and growing desire to solve this issue
  • No products on the market that both detect HABs and degrade microcystins
  • Revolutionizing current detection methods (inefficient direct water-testing)

Threats

  • Public’s negative perception of synthetic biology
  • Legal access to bodies of water with HABs, whether public or private, and gaining permissions to implement reHAB there
  • FDA/Government Regulations
FUTURE DEVELOPMENT
The most valuable aspect of any product lies in its intellectual property. Given that our project exists on the forefront of aptamer-based detection technology, we would aim to patent the novel components of our project through the Cornell Center for Technology Licensing (CTL). Of particular focus would be our detection system, the most unique dimension of our product.

The ingenuity and relevance of our project characterizes it as a necessary step in the right direction for harmful algal bloom mitigation. Our goal is to integrate our aptamer detection mechanism into large-scale systems in a way that other monitoring strategies have been unable to accomplish. According to the World Health Organization, there is an urgent need for the development of an animal friendly, rapid and cost-effective toxin analysis methodology for the future of microcystin detection. Our project has the potential to do just that.

In order to accomplish this, we plan to accomplish the following:
  • Further developing the aptamer-based detection system
  • Improving the automation of the boat system
  • Conducting market research to compile into case studies
  • Attaining resources for manufacturing and large-scale production
  • Reaching out to potential investors and buyers as well as affected community members